SGK
Serum and Glucocorticoid-Regulated Kinase (SGK) is a protein kinase involved in the regulation of various cellular processes, including ion transport, cell survival, and glucose metabolism. SGK inhibitors are valuable in the study of conditions such as hypertension, diabetes, and cancer, where SGK activity plays a crucial role. These inhibitors help in understanding the signaling pathways regulated by SGK and their implications in disease. At CymitQuimica, we offer SGK inhibitors to support your research in signal transduction, metabolic diseases, and cancer therapy.
Found 10 products of "SGK"
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SGK1-IN-3 hydrochloride
SGK1-IN-3 hydrochloride (compound 3a) is an efficacious, orally bioavailable SGK1 inhibitor. The serine/threonine kinase SGK1 acts as an activator of the β-catenin pathway and strongly stimulates cartilage degradation, being upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 hydrochloride holds potential for osteoarthritis research.Formula:C23H21Cl3N6O3SMolecular weight:566.04614308-R-C4-PEG3-C1-Boc
CAS:308-R-C4-PEG3-C1-Boc is an SGK3 ligand-linker conjugate, utilized in the synthesis of PROTAC SGK3 degrader-2.Formula:C39H53FN6O9SColor and Shape:SolidMolecular weight:800.94SGK1-IN-4
CAS:SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.Formula:C23H21ClFN5O4SPurity:97.03%Color and Shape:SolidMolecular weight:517.96Ref: TM-T9977
1mg105.00€5mg250.00€10mg356.00€25mg580.00€50mg782.00€100mg1,044.00€200mg1,404.00€1mL*10mM (DMSO)301.00€SI-113
CAS:SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades.Formula:C23H24N6OPurity:98.93%Color and Shape:SolidMolecular weight:400.48Ref: TM-T9589
1mg43.00€2mg56.00€5mg93.00€10mg133.00€25mg236.00€50mg354.00€100mg518.00€1mL*10mM (DMSO)101.00€CKI-7
CAS:CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H14Cl3N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:358.67Ref: TM-T19913
1mg108.00€5mg207.00€10mg309.00€25mg497.00€50mg675.00€100mg909.00€200mg1,224.00€1mL*10mM (DMSO)225.00€GSK 650394
CAS:GSK 650394 is an inhibitor of serum- and glucocorticoid-regulated kinases (SGK). GSK 650394 has antitumor activity. Cost-effective and quality-assured.Formula:C25H22N2O2Purity:97.46% - >99.99%Color and Shape:SolidMolecular weight:382.45Ref: TM-T2622
1mg38.00€2mg50.00€5mg84.00€10mg105.00€25mg197.00€50mg313.00€100mg447.00€200mg623.00€1mL*10mM (DMSO)93.00€EMD638683
CAS:EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 μM).Formula:C18H18F2N2O4Purity:98%Color and Shape:SolidMolecular weight:364.34Ref: TM-T6635
1mg74.00€2mg92.00€5mg150.00€10mg233.00€25mg358.00€50mg517.00€100mg737.00€200mg982.00€1mL*10mM (DMSO)120.00€SGK1-IN-1
CAS:SGK1-IN-1 (compound 14n) is a highly potent SGK1 (Serum/Glucocorticoid Regulated Kinase 1) inhibitorFormula:C17H12ClFN6O2SPurity:98%Color and Shape:SolidMolecular weight:418.83EMD638683 R-Form
CAS:EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 R-Form is the R-form of EMD638683.Formula:C18H18F2N2O4Color and Shape:SolidMolecular weight:364.34SGK1-IN-6
CAS:SGK1-IN-6 (compound 12f) is an SGK1 inhibitor with an IC50 value of 0.39 μM. In PC3 xenograft models using BALB/c nude mice, SGK1-IN-6 effectively hinders tumor growth without causing any observable toxicity.Formula:C30H30F3N5O4Color and Shape:SolidMolecular weight:581.586
