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Aminopeptidase

Aminopeptidase

Aminopeptidases are a group of enzymes that catalyze the cleavage of amino acids from the N-terminus of peptides and proteins, playing a crucial role in protein maturation and degradation. These enzymes are involved in various physiological processes, including antigen processing, peptide hormone regulation, and cellular homeostasis. Inhibitors of aminopeptidases are of interest in the treatment of diseases such as cancer, inflammation, and infectious diseases. At CymitQuimica, we provide a variety of aminopeptidase inhibitors to support your research in proteomics, drug development, and disease treatment.

Found 67 products of "Aminopeptidase"

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  • PPI-2458
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    PPI-2458

    CAS:
    <p>PPI-2458, a fumagillin derivative, irreversibly blocks MetAP2, hindering abnormal cell growth and angiogenesis with improved toxicity.</p>
    Formula:C22H36N2O6
    Color and Shape:Solid
    Molecular weight:424.53

    Ref: TM-T69258

  • QGC583
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    QGC583

    CAS:
    <p>QGC583 is an effective and selective AminopeptidaseA (APA) inhibitor, demonstrating an IC50 of 4 nM. It inhibits APA activity in the brain, kidneys, and heart of rats.</p>
    Formula:C13H20NO5P
    Color and Shape:Solid
    Molecular weight:301.28

    Ref: TM-T200621

  • 4-MDM
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    4-MDM

    CAS:
    <p>4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the aminopeptidase activity of leukotriene A4 hydrolase (LTA4H). By promoting the degradation of proline-glycine-proline by LTA4H, 4-MDM reduces neutrophil recruitment in the lungs, alleviating inflammation without affecting the epoxide hydrolase activity of LTA4H. This compound is useful for research in pulmonary diseases.</p>
    Formula:C14H14O
    Color and Shape:Solid
    Molecular weight:198.26

    Ref: TM-T204132

  • ERAP1 modulator-2
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    ERAP1 modulator-2

    CAS:
    <p>ERAP1 modulator-2 (compound 10) is a potent ERAP1 inhibitor with an IC50 value of less than 100 nM.</p>
    Formula:C22H25F3N2O4S
    Color and Shape:Solid
    Molecular weight:470.505

    Ref: TM-T204335

  • Beloranib
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    Beloranib

    CAS:
    <p>Beloranib is a fumagillin anticancer drug. Beloranib belongs to an angiogenesis inhibitor.</p>
    Formula:C29H41NO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:499.64

    Ref: TM-T19871

  • TNP-470
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    TNP-470

    CAS:
    <p>TNP-470 is a methionine aminopeptidase-2 inhibitor. TNP-470 is also an angiogenesis inhibitor.</p>
    Formula:C19H28ClNO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:401.88

    Ref: TM-T17110

  • Actinonin
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    Actinonin

    CAS:
    <p>Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. It also induces apoptosis and inhibits aminopeptidase M, aminopeptidase N, and leucine aminopeptidase, as well as MMP-1, MMP-3, MMP-8, MMP-9, and meprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin exhibits antiproliferative and antitumor activities [1][2][3][4][5].</p>
    Formula:C19H35N3O5
    Color and Shape:Solid
    Molecular weight:385.5

    Ref: TM-T14121

    1mg
    Discontinued
    Discontinued product