Casein Kinase
Casein kinases are a family of serine/threonine protein kinases that regulate various cellular processes, including DNA repair, circadian rhythms, and signal transduction. These kinases are involved in the phosphorylation of numerous proteins and are implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. At CymitQuimica, we offer a selection of casein kinase inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 143 products for "Casein Kinase".
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Casein kinase 1δ-IN-10
CAS:Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).Formula:C21H17N3O3Purity:98%Color and Shape:SolidMolecular weight:359.38Casein kinase 1δ-IN-4
CAS:Casein kinase 1δ-IN-4 is a selective CK1δ inhibitor; modulates circadian rhythm; used for sleep disorders and cancer.Formula:C16H12N6SPurity:99.89%Color and Shape:White SolidMolecular weight:320.37XL413 hydrochloride
CAS:XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7. XL413 hydrochloride also inhibits CK2 and PIM1.Formula:C14H13Cl2N3O2Purity:98.81% - 99.8%Color and Shape:SolidMolecular weight:326.18Ref: TM-T6735
1mg50.00€5mg109.00€10mg152.00€25mg268.00€50mg447.00€100mg672.00€200mg888.00€500mg1,369.00€Dinoxyline
CAS:Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.Formula:C15H13NO3Color and Shape:SolidMolecular weight:255.27Casein Kinase II Inhibitor IV Hydrochloride
CAS:Casein Kinase II Inhibitor IV HCl promotes keratinocyte differentiation, potential for skin disorder therapy.Formula:C24H24ClN5O3Purity:98%Color and Shape:SolidMolecular weight:465.93CK2-IN-3
CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.Formula:C22H26N4O7Color and Shape:SolidMolecular weight:458.46Casein kinase 1δ-IN-23
CAS:Casein kinase1δ-IN-23 (compound 423) is an effective inhibitor of casein kinase1δ. It is applicable in research related to neurodegenerative diseases such as Alzheimer's disease.Formula:C19H15N3O3SColor and Shape:SolidMolecular weight:365.406Casein kinase 1δ-IN-13
CAS:Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.Formula:C15H13N3O2SColor and Shape:SolidMolecular weight:299.35TMX-4113
TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1α(CK1α) degrader [1].Formula:C12H12N4O2S2Color and Shape:SolidMolecular weight:308.38Casein kinase 1δ-IN-17
CAS:Casein kinase1δ-IN-17 (compound 753) is an inhibitor of casein kinase 1δ (CK1δ). It is applicable in research related to neurodegenerative diseases.Formula:C14H14N4SColor and Shape:SolidMolecular weight:270.353Casein kinase 1δ-IN-28
CAS:Casein kinase1δ-IN-28 (Compound 4) is an inhibitor of CK1ε, with an IC50 of 0.0146 μM. The human liver microsome metabolism rate for Casein kinase1δ-IN-28 is 52%.Formula:C23H23FN6Color and Shape:SolidMolecular weight:402.467CK1δ-IN-6
CAS:CK1δ-IN-6 (Compound 303) is an inhibitor of Casein kinase 1δ, with potential applications in Alzheimer's disease research.Formula:C23H17N3O4Color and Shape:SolidMolecular weight:399.399WAY-606344
CAS:WAY-606344 (Compound 97) is an inhibitor of Casein kinase 1δ and shows potential for Alzheimer's disease research.Formula:C14H8ClN3O2Color and Shape:SolidMolecular weight:285.685CK1δ-IN-5
CAS:CK1δ-IN-5 (Compound 24) is an inhibitor of casein kinase 1δ (CK1δ) and can be used in the study of neurodegenerative diseases.Formula:C22H21N5Color and Shape:SolidMolecular weight:355.436Casein kinase 1δ-IN-27
CAS:Casein kinase1δ-IN-27 (Compound 8) is an inhibitor of casein kinase 1 (CK1), effectively inhibiting CK1α, CK1δ, CK1ε, and p38α with IC50 values of 22, 16.5, 9.41, and 14.8 nM, respectively. It also suppresses DUX4 expression, with an IC50 of 10 nM.Formula:C21H19FN6Color and Shape:SolidMolecular weight:374.414CK1δ-IN-7
CAS:CK1δ-IN-7 (Compound 488) is an inhibitor of casein kinase 1δ (CK1δ).Formula:C23H23N5OColor and Shape:SolidMolecular weight:385.462p38α inhibitor 8
CAS:p38α inhibitor8 (Compound 1) demonstrates inhibitory activity against p38αMAPK and CK1δ, with IC50 values of 0.21 µM and 0.202 µM, respectively.Formula:C17H13FN6Color and Shape:SolidMolecular weight:320.324BMS-135
CAS:BMS-135 is a potent and selective ATP-competitive inhibitor of casein kinase 2 (CK2), with IC50 values of 0.8 nM for CK2α and 0.3 nM for CK2α' isoforms. It mimics the structure of ATP, binding to the active site of CK2 and inhibiting its serine/threonine phosphorylating activity. BMS-135 effectively inhibits cell proliferation and demonstrates antitumor properties, making it useful for research in colon cancer.Formula:C22H23ClN10O3Molecular weight:510.94dCK1α-2
dCK1α-2 is an orally effective CK1α molecular glue (Molecular Glue) degrader that targets p53 pathway-related targets. It demonstrates antitumor efficacy in mouse models by enhancing the expression of p53-related genes.Formula:C24H24ClN5O4Color and Shape:SolidMolecular weight:481.93CK1δ-IN-9
CAS:CK1δ-IN-9 (Compound 8) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ with an IC50 of 1.4 nM. The compound also inhibits p38α and p38β with IC50 values of 0.25 μM and 0.78 μM, respectively. CK1δ-IN-9 exhibits favorable pharmacokinetic properties, including high oral bioavailability (70%) and moderate clearance.Formula:C16H12FN5Color and Shape:SolidMolecular weight:293.298
