Casein Kinase
Casein kinases are a family of serine/threonine protein kinases that regulate various cellular processes, including DNA repair, circadian rhythms, and signal transduction. These kinases are involved in the phosphorylation of numerous proteins and are implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. At CymitQuimica, we offer a selection of casein kinase inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 150 products for "Casein Kinase".
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AMG-548
CAS:AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.Formula:C29H27N5OPurity:99.91%Color and Shape:SolidMolecular weight:461.56BTX161
CAS:BTX161: potent CKIα degrader, surpasses Lenalidomide in AML, triggers DDR + p53, stabilizes MDM2.Formula:C15H16N2O3Color and Shape:SolidMolecular weight:272.3CK2/PIM1-IN-1
CAS:CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.Formula:C15H9NO4S2Purity:98%Color and Shape:SolidMolecular weight:331.366HDAC/CK2-IN-1
CAS:HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.Formula:C15H18Br4N4O2Color and Shape:SolidMolecular weight:605.95Quinalizarin
CAS:Quinalizarin, the most selective CK2 inhibitor, is superior to CX-4945 which is the first-in-class CK2 inhibitor.Formula:C14H8O6Purity:98%Color and Shape:SolidMolecular weight:272.21CK2-IN-4
CAS:CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM.Formula:C18H11N3O4SPurity:99.65%Color and Shape:SolidMolecular weight:365.36CK2α-IN-1
CAS:CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and canFormula:C16H11N3O4SPurity:98%Color and Shape:SolidMolecular weight:341.34HS-276
CAS:HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Formula:C24H29N5O2Purity:97.67% - 98.81%Color and Shape:SolidMolecular weight:419.52BioE-1115
CAS:BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).Formula:C19H18FN3O2Purity:97.54%Color and Shape:SolidMolecular weight:339.36Casein kinase 1δ-IN-1
CAS:Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ.Formula:C11H7N3OSPurity:99.89%Color and Shape:White SolidMolecular weight:229.26PI-828
CAS:PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.Formula:C19H18N2O3Purity:99.95%Color and Shape:White SolidMolecular weight:322.36Ref: TM-T16528
1mg34.00€1mL*10mM (DMSO)52.00€5mg73.00€10mg111.00€25mg187.00€50mg268.00€100mg366.00€200mg522.00€XL413 xHCl
CAS:BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215Formula:C14H12ClN3O2·xHClPurity:99.37% - 99.48%Color and Shape:SolidMolecular weight:326.18BAY-204
CAS:BAY-204 is a CSNK1α/δ inhibitor that can be used in the treatment of proliferative diseases.Formula:C29H26F3N5O2Color and Shape:SolidMolecular weight:533.54TID43
CAS:TID43, a CK2 inhibitor, exhibits potent inhibition with an IC50 value of 0.3 μM. It is applicable in anti-angiogenic research [1].Formula:C10H3I4NO4Color and Shape:SolidMolecular weight:708.755ON 108600
CAS:ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.Formula:C22H14Cl2N2O6S2Purity:98%Color and Shape:SolidMolecular weight:537.39PF-05236216
CAS:PF-05236216 is a potent, selective, brain-penetrant CK1δ/ε inhibitor that modulates circadian rhythms in mice, supporting sleep and metabolic research.Formula:C18H15FN4OPurity:100% - 100%Color and Shape:White SolidMolecular weight:322.34Casein kinase 1δ-IN-5
CAS:Casein kinase 1δ-IN-5 is a selective CK1δ inhibitor (IC50 47 nM) with neuroprotective activity, supporting neurodegeneration research.Formula:C16H11F3N2OSPurity:99.62%Color and Shape:White SolidMolecular weight:336.33CK2-IN-11
CAS:CK2-IN-11 (32) acts as an allosteric inhibitor of CK2, with IC50 values of 19.3 nM for the CK2α2β2 isoform and 15.6 nM for the CK2α'2β2 isoform.Formula:C23H22Br4Cl2N4O2Color and Shape:SolidMolecular weight:776.97Casein kinase 1δ-IN-4
CAS:Casein kinase 1δ-IN-4 is a selective CK1δ inhibitor; modulates circadian rhythm; used for sleep disorders and cancer.Formula:C16H12N6SPurity:99.89%Color and Shape:White SolidMolecular weight:320.37Casein Kinase II Inhibitor IV
CAS:Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.Formula:C24H23N5O3Purity:99.65% - 99.75%Color and Shape:SolidMolecular weight:429.47Ref: TM-T10687
1mg82.00€5mg161.00€1mL*10mM (DMSO)172.00€10mg245.00€25mg405.00€50mg572.00€100mg772.00€500mg1,539.00€
