Factor Xa
Factor Xa is a crucial enzyme in the coagulation cascade that converts prothrombin to thrombin, leading to blood clot formation. Inhibition of Factor Xa is a widely used therapeutic strategy for preventing and treating thromboembolic disorders, such as deep vein thrombosis, pulmonary embolism, and stroke. At CymitQuimica, we offer Factor Xa inhibitors to support your research in hematology, cardiovascular health, and anticoagulant therapy.
Found 87 products of "Factor Xa"
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Betrixaban
CAS:Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.Formula:C23H22ClN5O3Purity:99.33%Color and Shape:SolidMolecular weight:451.91Ref: TM-T4341
2mg44.00€5mg66.00€10mg90.00€25mg164.00€50mg268.00€100mg430.00€500mg945.00€1mL*10mM (DMSO)73.00€Milvexian
CAS:Milvexian (BMS-986177) is an oral antithrombotic, reversibly inhibiting human/rabbit FXIa with K i of 0.11/0.38 nM.Formula:C28H23Cl2F2N9O2Color and Shape:SolidMolecular weight:626.45Milvexian TFA
CAS:Milvexian (BMS-986177/JNJ-70033093) is a factor XIa inhibitor with Ki=44 nM for kallikrein, Ki=35 nM for chymotrypsin, 32% bioavailability.Formula:C30H26Cl2F5N9O4Color and Shape:SolidMolecular weight:742.49YM-75466
CAS:YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.Formula:C28H35N5O8S2Color and Shape:SolidMolecular weight:633.74Pegnivacogin
CAS:Pegnivacogin is a coagulation factor IXa RNA aptamer inhibitor.Formula:C20H40N3O11PPurity:98%Color and Shape:SolidMolecular weight:529.52Ciraparantag TFA
CAS:Ciraparantag TFA reverses anticoagulants by inhibiting thrombin and factor Xa.Formula:C26H50F6N12O6Purity:98%Color and Shape:SolidMolecular weight:740.74BMS 740808
CAS:BMS-740808 is a highly effective and selective factor X inhibitor.Formula:C31H27F3N6O3Color and Shape:SolidMolecular weight:588.58Ciraparantag
CAS:Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.Formula:C22H48N12O2Purity:98%Color and Shape:SolidMolecular weight:512.7Darexaban glucuronide
CAS:Darexaban glucuronide is the major component in plasma after oral administration of darexaban to humans. Darexaban (YM150) is a direct inhibitor of factor Xa.Formula:C33H38N4O10Color and Shape:SolidMolecular weight:650.68Tanogitran
CAS:Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.Formula:C25H31N7O3Purity:98%Color and Shape:SolidMolecular weight:477.56DPC-423
CAS:DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.Formula:C25H21ClF4N4O3SPurity:98%Color and Shape:SolidMolecular weight:568.97Razaxaban hydrochloride
CAS:Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.Formula:C24H21ClF4N8O2Purity:98%Color and Shape:SolidMolecular weight:564.92Otamixaban
CAS:Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.Formula:C25H26N4O4Purity:98.08%Color and Shape:SolidMolecular weight:446.5Eribaxaban
CAS:Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.Formula:C24H22ClFN4O4Purity:98.99% - 99.13%Color and Shape:SolidMolecular weight:484.91LY 517717
CAS:LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).Formula:C27H33N5O2Purity:99.77% - 99.88%Color and Shape:SolidMolecular weight:459.58Edoxaban
CAS:Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.Formula:C24H30ClN7O4SPurity:97.67% - 99.71%Color and Shape:SolidMolecular weight:548.06Fidexaban
CAS:Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assaysFormula:C25H24F2N6O5Purity:97.27% - 99.43%Color and Shape:SolidMolecular weight:526.49Zifaxaban
CAS:Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.Formula:C20H16ClN3O4SPurity:97.46% - 99.82%Color and Shape:SolidMolecular weight:429.88Ref: TM-T29215
1mg315.00€5mg745.00€10mg1,018.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,410.00€Frunexian
CAS:Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.Formula:C19H26N4O4Purity:98%Color and Shape:SolidMolecular weight:374.43BMS-262084
CAS:BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.Formula:C18H31N7O5Color and Shape:SolidMolecular weight:425.48FXIa-IN-1
CAS:FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.Formula:C20H19F3N4O5Purity:98%Color and Shape:SolidMolecular weight:452.38AS1468240
CAS:AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.Formula:C25H25Cl2N5O3Color and Shape:SolidMolecular weight:514.4FXa-IN-1
CAS:FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.Formula:C24H18F5N5OColor and Shape:SolidMolecular weight:487.42FXIa-IN-7
CAS:FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.Formula:C28H28N2O4Purity:98.55%Color and Shape:SolidMolecular weight:456.53BI-11634
CAS:BI-11634 is a factor Xa inhibitor.Formula:C22H23ClN4NaO4Purity:98%Color and Shape:SolidMolecular weight:465.89BMS-654457
CAS:BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).Formula:C36H37N5O4Purity:98%Color and Shape:SolidMolecular weight:603.71BMS-962212
CAS:BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.Formula:C32H28ClFN8O5Purity:98%Color and Shape:SolidMolecular weight:659.07Dechloro Rivaroxaban
CAS:Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.Formula:C19H19N3O5SPurity:98.63%Color and Shape:SolidMolecular weight:401.44Ref: TM-T78215
5mg40.00€10mg63.00€25mg107.00€50mg170.00€100mg264.00€200mg418.00€1mL*10mM (DMSO)44.00€FXIa-IN-9
CAS:FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.Formula:C23H18Cl2F3N9O2Color and Shape:SolidMolecular weight:580.35FXIa-6f
CAS:FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical speciesFormula:C31H29ClF2N4O4Color and Shape:SolidMolecular weight:595.04RWJ-445167
CAS:RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.Formula:C18H24N6O5SPurity:98%Color and Shape:SolidMolecular weight:436.49FXIa-IN-6
CAS:FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.Formula:C31H29ClF2N4O4Color and Shape:SolidMolecular weight:595.04FXIa-IN-8
FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.Color and Shape:SolidFXIa-IN-10
FXIa-IN-10 is a potent, orally bioavailable inhibitor of Activator XI (FXIa) (Ki: 0.17 nM).Formula:C23H18Cl2F3N9O2Color and Shape:SolidMolecular weight:580.35BAY 3389934
CAS:BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.Formula:C26H30ClN5O7S2Color and Shape:SolidMolecular weight:624.129DX-9065A HCl hydrate
CAS:DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.Formula:C26H39ClN4O8Purity:98%Color and Shape:SolidMolecular weight:571.065-Chlorothiophene-2-carboxylic acid
CAS:5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.Formula:C5H3ClO2SColor and Shape:SolidMolecular weight:162.59
