Factor Xa
Factor Xa is a crucial enzyme in the coagulation cascade that converts prothrombin to thrombin, leading to blood clot formation. Inhibition of Factor Xa is a widely used therapeutic strategy for preventing and treating thromboembolic disorders, such as deep vein thrombosis, pulmonary embolism, and stroke. At CymitQuimica, we offer Factor Xa inhibitors to support your research in hematology, cardiovascular health, and anticoagulant therapy.
Found 80 products of "Factor Xa"
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Edoxaban
CAS:<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Formula:C24H30ClN7O4SPurity:97.67% - 99.71%Color and Shape:SolidMolecular weight:548.06Zifaxaban
CAS:<p>Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.</p>Formula:C20H16ClN3O4SPurity:97.46% - 99.82%Color and Shape:SolidMolecular weight:429.88BMS-262084
CAS:<p>BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.</p>Formula:C18H31N7O5Color and Shape:SolidMolecular weight:425.48FXIa-IN-1
CAS:<p>FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.</p>Formula:C20H19F3N4O5Purity:98%Color and Shape:SolidMolecular weight:452.38Frunexian
CAS:<p>Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.</p>Formula:C19H26N4O4Purity:98%Color and Shape:SolidMolecular weight:374.43AS1468240
CAS:<p>AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.</p>Formula:C25H25Cl2N5O3Color and Shape:SolidMolecular weight:514.4BI-11634
CAS:<p>BI-11634 is a factor Xa inhibitor.</p>Formula:C22H23ClN4NaO4Purity:98%Color and Shape:SolidMolecular weight:465.89BMS-962212
CAS:<p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>Formula:C32H28ClFN8O5Purity:98%Color and Shape:SolidMolecular weight:659.07FXIa-IN-7
CAS:<p>FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.</p>Formula:C28H28N2O4Purity:98.55%Color and Shape:SolidMolecular weight:456.53BMS-654457
CAS:<p>BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).</p>Formula:C36H37N5O4Purity:98%Color and Shape:SolidMolecular weight:603.71FXa-IN-1
CAS:<p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>Formula:C24H18F5N5OColor and Shape:SolidMolecular weight:487.42Dechloro Rivaroxaban
CAS:<p>Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.</p>Formula:C19H19N3O5SPurity:98.63%Color and Shape:SolidMolecular weight:401.44DX-9065A HCl hydrate
CAS:<p>DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.</p>Formula:C26H39ClN4O8Purity:98%Color and Shape:SolidMolecular weight:571.06BAY 3389934
CAS:<p>BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.</p>Formula:C26H30ClN5O7S2Color and Shape:SolidMolecular weight:624.129RWJ-445167
CAS:<p>RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.</p>Formula:C18H24N6O5SPurity:98%Color and Shape:SolidMolecular weight:436.49FXIa-6f
CAS:<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Formula:C31H29ClF2N4O4Color and Shape:SolidMolecular weight:595.04FXIa-IN-6
CAS:<p>FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.</p>Formula:C31H29ClF2N4O4Color and Shape:SolidMolecular weight:595.04FXIa-IN-9
CAS:<p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>Formula:C23H18Cl2F3N9O2Color and Shape:SolidMolecular weight:580.35FXIa-IN-8
<p>FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.</p>Color and Shape:Solid5-Chlorothiophene-2-carboxylic acid
CAS:<p>5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.</p>Formula:C5H3ClO2SColor and Shape:SolidMolecular weight:162.59
