Carbonic Anhydrase
Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.
Found 196 products of "Carbonic Anhydrase"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Bendroflumethiazide
CAS:Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)Formula:C15H14F3N3O4S2Purity:98% - >99.99%Color and Shape:Crystals From Dioxane SolidMolecular weight:421.41hCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5hCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5CAIX-IN-4
CAIX-IN-4 (Compound 8b) is a selective inhibitor of carbonic anhydrase IX (CAIX) with an IC50 value of 0.32 μM. It holds potential for research in cancer, such as renal cell carcinoma.Color and Shape:Odour SolidhCA-I/hCA-II-IN-1
hCA-I/hCA-II-IN-1 (Compound P4) is a potent dual inhibitor of human carbonic anhydrase I (hCA-I) and human carbonic anhydrase II (hCA-II), with Ki values of 0.22 μM and 0.33 μM respectively. hCA-I/hCA-II-IN-1 is useful for research into diseases related to CA enzymes, including glaucoma, hypertension, and ulcers.Color and Shape:Odour SolidCarbonic anhydrase inhibitor 26
Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.Formula:C17H14N6O4Color and Shape:SolidMolecular weight:366.33Phenylsulfamide
CAS:Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and anFormula:C6H8N2O2SColor and Shape:SolidMolecular weight:172.2AV22-149
AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .Formula:C23H28F3N3O6S2Color and Shape:SolidMolecular weight:563.61α-Glycosidase-IN-2
α-Glycosidase-IN-2 (compound 8b) is an inhibitor of α-glycosidase, displaying Ki values of 74.16 nM and 6.09 nM for aldose reductase and α-glycosidase, respectively. This compound is utilized in research related to diabetes.Formula:C25H22N6OS2Color and Shape:SolidMolecular weight:486.61CA Ⅱ-IN-1
CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.Formula:C18H19NO6SColor and Shape:SolidMolecular weight:377.41hCAXII-IN-9
hCAXII-IN-9 (Compound 3I) is a selective hCAXII inhibitor with Ki values of 28 nM for hCAXII, 7192.6 nM for hCAI, 188.6 nM for hCAII, and greater than 100000 nM for hCAIX. This compound may be utilized in anti-tumor research.Formula:C24H30N3O7PSMolecular weight:535.15421(Iso)-Samixogrel
CAS:(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.Formula:C25H25ClN2O4SPurity:98.85%Color and Shape:SolidMolecular weight:484.99Carbonic anhydrase inhibitor 24
Carbonic anhydrase inhibitor24 (Compound 11) is an inhibitor of human carbonic anhydrase. It exhibits Ki values of 10.7 nM and 7.5 nM against hCAs IX and XII, respectively.Formula:C16H14Cl2N2O6SMolecular weight:431.99496Acesulfame
CAS:Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formula:C4H5NO4SColor and Shape:SolidMolecular weight:163.15Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Formula:C26H28N4O6S2Molecular weight:556.14503Carbonic anhydrase inhibitor 21
Compound 5h, known as Carbonic anhydrase inhibitor 21, is a specific inhibitor of carbonic anhydrase (hCA IX) with a K\(_i\) of 15.1 nM, demonstrating high selectivity compared to other isoforms studied. This compound is utilized in anticancer research.Formula:C32H48N4O10P2S2Molecular weight:774.22871hCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Formula:C13H10FN3O4Molecular weight:291.06553Chlorthalidone Impurity G
CAS:Chlorthalidone impurity G, a thiazide-like diuretic's contaminant, has mild antihypertensive properties and inhibits several carbonic anhydrase isoforms.Formula:C14H9Cl2NO2Color and Shape:SolidMolecular weight:294.13GZ22-4
GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.Formula:C88H126F3N6NaO24S4Molecular weight:1858.75561Girentuximab
CAS:Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Color and Shape:LiquidMolecular weight:145.55 kDahCAIX/XII-IN-10
hCAIX/XII-IN-10 (compound DK-8) is an inhibitor of Carbonic Anhydrase, showing potent inhibitory activity against the tumor-associated membrane-bound isoforms hCA IX and XII, with Ki values of 32.5 nM and 29.2 nM, respectively.Formula:C17H13N3O5SMolecular weight:371.05759CAII/CAXII-IN-1
CAII/CAXII-IN-1 (compound 8d) is an inhibitor of CAII and CAXII, with IC50 values of 0.38 µM for CAII and 0.61 µM for CAXII.Color and Shape:Odour SolidChlorzolamide
CAS:CHLORZOLAMIDE is a sulfonamide-based inhibitor that exhibits cytotoxic effects on prostate cancer cells.Formula:C8H6ClN3O2S2Molecular weight:275.74hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.Formula:C22H20N4O6S2Color and Shape:SolidMolecular weight:500.547hCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.Formula:C23H22N4O7S2Color and Shape:SolidMolecular weight:530.573M 12325
CAS:M 12325 is used in the production of furosemide; rhinitis and occupational asthma were observed in workers from a lasamide production line.Formula:C7H5Cl2NO4SColor and Shape:White To Almost White Solid PowderMolecular weight:270.09Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.Color and Shape:Lyophilized PowderMolecular weight:32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Acetazolamide-d3
CAS:Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.Formula:C4H6N4O3S2Purity:98%Color and Shape:SolidMolecular weight:225.26Trichlormethiazide (Standard)
CAS:Trichlormethiazide (Standard) is the standard substance of Trichlormethiazide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.Formula:C8H8Cl3N3O4S2Molecular weight:380.664-Chloro-3-sulfamoylbenzoic acid
CAS:Compound PDK0044, with CAS No. 1205-30-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0044 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C7H6ClNO4SColor and Shape:White PowderMolecular weight:235.642,3-dihydro-1H-indene-5-sulfonamide
CAS:2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.Formula:C9H11NO2SPurity:99.89%Color and Shape:SolidMolecular weight:197.25Ref: TM-T8611
1mg62.00€5mg123.00€10mg180.00€25mg298.00€50mg419.00€100mg567.00€200mg752.00€1mL*10mM (DMSO)104.00€Ethoxzolamide
CAS:Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.Formula:C9H10N2O3S2Purity:98.27% - 99.62%Color and Shape:Crystals From Ethyl Acetate + Skellysolve B SolidMolecular weight:258.32Fluorometholone Acetate
CAS:Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.Formula:C24H31FO5Purity:99.76%Color and Shape:SolidMolecular weight:418.50Dichlorphenamide
CAS:Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.Formula:C6H6Cl2N2O4S2Purity:96.87% - 97.25%Color and Shape:Needles From Dimethylsulfoxide + Water SolidMolecular weight:305.16Ref: TM-T6469
5mg52.00€10mg62.00€25mg82.00€50mg90.00€100mg133.00€200mg190.00€500mg323.00€1mL*10mM (DMSO)56.00€4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS:4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-Formula:C7H8F3N3O4S2Purity:98.58%Color and Shape:SolidMolecular weight:319.28Brinzolamide hydrochloride
Brinzolamide (AL-4862) HCl selectively inhibits carbonic anhydrase II, reducing IOP for glaucoma research. IC50: 3.2 nM.Color and Shape:SolidU-104
CAS:U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).
Formula:C13H12FN3O3SPurity:98.76% - 99.88%Color and Shape:SolidMolecular weight:309.32Dimethylfraxetin
CAS:Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki：0.0097 μM)Formula:C12H12O5Purity:99.96% - ≥95%Color and Shape:SolidMolecular weight:236.22Dichlorphenamide disodium
CAS:Dichlorphenamide disodium: an oral carbonic anhydrase inhibitor that lowers eye pressure, promising for glaucoma study.Formula:C6H6Cl2N2Na2O4S2Color and Shape:SolidMolecular weight:351.12Orthanilamide
CAS:Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.Formula:C6H8N2O2SPurity:99.72% - 99.96%Color and Shape:White To Pale Cream Crystalline Powder Or CrystalsMolecular weight:172.2Trichlormethiazide sodium
CAS:Trichlormethiazide sodium: oral thiazide diuretic, antihypertensive, boosts urine, Na/K excretion, may enhance renal clearance.Formula:C8H8Cl3N3NaO4S2Color and Shape:SolidMolecular weight:403.63Taselisib
CAS:Taselisib (GDC-0032) is an oral PI3K alpha inhibitor with potential cancer-treating properties.Formula:C24H28N8O2Purity:99.62% - 99.79%Color and Shape:SolidMolecular weight:460.53Ref: TM-T1999
2mg46.00€5mg66.00€10mg92.00€25mg157.00€50mg197.00€100mg350.00€200mg522.00€500mg840.00€1mL*10mM (DMSO)66.00€Zolamide
CAS:Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.Formula:C2H4N4O2S2Purity:99.75%Color and Shape:SolidMolecular weight:180.21Acipimox sodium
CAS:Acipimox sodium is an antilipolytic, enhancing leptin, curbing lipolysis and FFAs, and boosting insulin sensitivity.Formula:C6H5N2NaO3Color and Shape:SolidMolecular weight:176.11Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Formula:C6H7NO2SPurity:99.42% - 99.99%Color and Shape:White Crystalline PowderMolecular weight:157.19Dorzolamide hydrochloride
CAS:Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme thatFormula:C10H17ClN2O4S3Purity:99.48% - 99.67%Color and Shape:White Off-White Crystalline PowderMolecular weight:360.9Methyclothiazide
CAS:Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions includingFormula:C9H11Cl2N3O4S2Purity:99.13%Color and Shape:SolidMolecular weight:360.24Polmacoxib
CAS:Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.Formula:C18H16FNO4SPurity:97.88%Color and Shape:SolidMolecular weight:361.39Ref: TM-T21294
2mg44.00€5mg66.00€10mg102.00€25mg170.00€50mg245.00€100mg358.00€200mg533.00€1mL*10mM (DMSO)73.00€Indisulam
CAS:Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formula:C14H12ClN3O4S2Purity:98.68% - 99.77%Color and Shape:SolidMolecular weight:385.85Ref: TM-T4321
1mg34.00€2mg43.00€5mg63.00€10mg88.00€25mg130.00€50mg198.00€100mg298.00€1mL*10mM (DMSO)69.00€Benzolamide
CAS:Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.Formula:C8H8N4O4S3Purity:99.31%Color and Shape:SolidMolecular weight:320.37Ref: TM-T23782
5mg49.00€10mg84.00€25mg152.00€50mg222.00€100mg331.00€200mg489.00€1mL*10mM (DMSO)54.00€
