Carbonic Anhydrase
Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.
Found 196 products of "Carbonic Anhydrase"
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CAII-IN-3
CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.Formula:C18H18F2N4SColor and Shape:SolidMolecular weight:360.42β-Glucuronidase/hCAII-IN-2
β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.Formula:C31H23NO8Color and Shape:SolidMolecular weight:537.52Carbonic anhydrase inhibitor 2
CAS:Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.Formula:C12H16N4O6SColor and Shape:SolidMolecular weight:344.34hCAII-IN-4
CAS:hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.Formula:C31H23NO9Color and Shape:SolidMolecular weight:553.52Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].Formula:C15H17N3O3SColor and Shape:SolidMolecular weight:319.38Valerate sodium
CAS:Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.
Formula:C5H9NaO2Purity:99.84%Color and Shape:SolidMolecular weight:124.11Carbonic anhydrase inhibitor 16
CAS:Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.Formula:C14H10N2O4SPurity:99.65%Color and Shape:SolidMolecular weight:302.31hCAIX-IN-20
CAS:hCAIX-IN-20 (compound APBS-5m) is a potent inhibitor of carbonic anhydrase IX (hCA IX), with a Ki of 2.7 nM, playing a significant role in cancer research.Formula:C19H13Cl2N5O4S2Molecular weight:510.37Carbonic anhydrase inhibitor 17
CAS:Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.Formula:C18H15ClN4O3S2Molecular weight:434.92Carbonic anhydrase inhibitor 19
CAS:Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.Formula:C23H25N3O6S2Molecular weight:503.59α-Glucosidase-IN-63
CAS:α-Glucosidase-IN-63 (Compound 4d) serves as an α-Glucosidase inhibitor with an IC 50 value of 0.44 μM. Additionally, it exhibits inhibitory activity against hCA II, demonstrating a K i of 7.0 nM. The compound is also effective when administered orally. [1]Formula:C16H12FN3O3S2Color and Shape:SolidMolecular weight:377.41EGFR/VEGFR2-IN-2
EGFR/VEGFR2-IN-2 (compound 4b) serves as a dual inhibitor of VEGFR-2 and EGFR.Formula:C24H15FO3Color and Shape:SolidMolecular weight:370.37Sulclamide
CAS:Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].Formula:C7H7ClN2O3SColor and Shape:SolidMolecular weight:234.664-Acetylphenylboronic acid
CAS:4-Acetylphenylboronic acid acts as an effective inhibitor targeting carbonic anhydrase II (CAII), displaying inhibitory concentrations (IC50) of 246 μM for bovine CAII (bCA II) and 281.40 μM for human CAII (hCA II).Formula:C8H9BO3Color and Shape:SolidMolecular weight:163.97O-Desmethyl Brinzolamide hydrochloride
CAS:O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].Formula:C11H20ClN3O5S3Color and Shape:SolidMolecular weight:405.94Carbonic anhydrase inhibitor 8
R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).Formula:C20H25N3O4SColor and Shape:SolidMolecular weight:403.5
