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Carbonic Anhydrase

Carbonic Anhydrase

Carbonic anhydrase is an enzyme that catalyzes the reversible conversion of carbon dioxide and water into bicarbonate and protons. This enzyme plays a crucial role in maintaining acid-base balance, respiration, and the transport of carbon dioxide in the blood. Inhibitors of carbonic anhydrase are used in the treatment of glaucoma, epilepsy, and altitude sickness, as well as in research on acid-base homeostasis and gas exchange. At CymitQuimica, we offer a range of high-quality carbonic anhydrase inhibitors and reagents to support your research in enzymology, respiratory physiology, and therapeutic development.

Found 177 products of "Carbonic Anhydrase"

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  • Orthanilamide

    CAS:
    <p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>
    Formula:C6H8N2O2S
    Purity:99.72% - 99.96%
    Color and Shape:White To Pale Cream Crystalline Powder Or Crystals
    Molecular weight:172.2
  • Indisulam

    CAS:
    <p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>
    Formula:C14H12ClN3O4S2
    Purity:98.68% - 99.77%
    Color and Shape:Solid
    Molecular weight:385.85
  • U-104

    CAS:
    <p>U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).</p>
    Formula:C13H12FN3O3S
    Purity:98.76% - 99.88%
    Color and Shape:Solid
    Molecular weight:309.32
  • Ethoxzolamide

    CAS:
    <p>Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.</p>
    Formula:C9H10N2O3S2
    Purity:98.27% - 99.62%
    Color and Shape:Crystals From Ethyl Acetate + Skellysolve B Solid
    Molecular weight:258.32
  • Polmacoxib

    CAS:
    <p>Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.</p>
    Formula:C18H16FNO4S
    Purity:97.88%
    Color and Shape:Solid
    Molecular weight:361.39
  • Fluorometholone Acetate

    CAS:
    <p>Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.</p>
    Formula:C24H31FO5
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:418.50
  • GV2-20

    CAS:
    <p>GV2-20 is an effective carbonic anhydrase 2 inhibitors.</p>
    Formula:C15H13N3O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:331.28
  • Disulfamide

    CAS:
    <p>Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.</p>
    Formula:C7H9ClN2O4S2
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:284.74
  • HCAIX-IN-2

    CAS:
    <p>HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).</p>
    Formula:C19H16N8O4S
    Color and Shape:Solid
    Molecular weight:452.45
  • hCAIX-IN-11

    CAS:
    <p>hCAIX-IN-11 inhibits carbonic anhydrases IX &amp; XII with Ki of 32.7 nM &amp; 623.5 nM, respectively.</p>
    Formula:C21H15ClN4O3
    Color and Shape:Solid
    Molecular weight:406.82
  • hCAI/II-IN-1

    CAS:
    <p>hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).</p>
    Formula:C18H29N5O3S3
    Color and Shape:Solid
    Molecular weight:459.65
  • hCAIX/XII-IN-2

    CAS:
    <p>Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); &gt;10,000 nM (hCAI/II).</p>
    Formula:C19H14N2O4
    Color and Shape:Solid
    Molecular weight:334.33
  • CDK2-IN-12

    CAS:
    <p>CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.</p>
    Formula:C20H17N9O2S
    Color and Shape:Solid
    Molecular weight:447.47
  • Clofenamide

    CAS:
    <p>Clofenamide is a low-ceiling sulfonamide diuretic.</p>
    Formula:C6H7ClN2O4S2
    Color and Shape:Solid
    Molecular weight:270.71
  • hCAII-IN-2

    CAS:
    <p>hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.</p>
    Formula:C25H18ClN5O4S
    Color and Shape:Solid
    Molecular weight:519.96
  • hCAIX/XII-IN-3

    CAS:
    <p>Compound 6q inhibits hCAIX/CAXII; K i : hCAI &gt;10000 nM, hCAII &gt;10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.</p>
    Formula:C20H13F3N2O4
    Color and Shape:Solid
    Molecular weight:402.32
  • CDK2-IN-11

    CAS:
    <p>CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.</p>
    Formula:C18H14ClN7O2S
    Color and Shape:Solid
    Molecular weight:427.87
  • hCA I-IN-1

    CAS:
    <p>hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).</p>
    Formula:C27H23N5O4S
    Color and Shape:Solid
    Molecular weight:513.57
  • hCAXII-IN-3

    CAS:
    <p>hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).</p>
    Formula:C26H20BrN5O3S
    Color and Shape:Solid
    Molecular weight:562.44
  • Carbonic anhydrase inhibitor 14

    CAS:
    <p>CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.</p>
    Formula:C18H17N7O2S
    Color and Shape:Solid
    Molecular weight:395.44