HMG-CoA Reductase
HMG-CoA Reductase is a key enzyme in the mevalonate pathway, responsible for the synthesis of cholesterol and other isoprenoids. Inhibitors of HMG-CoA reductase, commonly known as statins, are widely used to lower cholesterol levels and reduce the risk of cardiovascular diseases. These inhibitors also have potential benefits in cancer and neurodegenerative disease research. At CymitQuimica, we provide a variety of HMG-CoA reductase inhibitors to support your research in lipid metabolism, cardiovascular health, and therapeutic development.
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Pitavastatin lactone
CAS:141750-63-2
Pitavastatin lactone, a major human metabolite, potently inhibits HMG-CoA reductase with minimal hepatic microsome metabolism.
Formula:
C25H22FNO3
Purity:
98.20%
Color and Shape:
White To Off-White Powder
Molecular weight:
403.45
Ref: TM-T12490
| 5mg | 47.00 € | ||
| 10mg | 65.00 € | ||
| 25mg | 126.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 283.00 € | ||
| 200mg | 424.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Tert-Buthyl Pitavastatin
CAS:586966-54-3
Tert-Buthyl Pitavastatin is a metabolite of Pitavastatin, a potent HMG-CoA reductase inhibitor.
Formula:
C29H32FNO4
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
477.57
Ref: TM-T13131
| 200mg | 34.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Atorvastatin lactone
CAS:125995-03-1
Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme …
Formula:
C33H33FN2O4
Purity:
98.16%
Color and Shape:
Solid
Molecular weight:
540.62
Ref: TM-T14342
| 2mg | 38.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 136.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 283.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Anhydrosimvastatin
CAS:210980-68-0
Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.
Formula:
C25H36O4
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
400.55
Ref: TM-T10324
| 1mg | 137.00 € | ||
| 5mg | 298.00 € | ||
| 10mg | 430.00 € | ||
| 25mg | 652.00 € | ||
| 50mg | 900.00 € | ||
| 100mg | 1,206.00 € | ||
| 1mL*10mM (DMSO) | 328.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Monacolin J
CAS:79952-42-4
Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.
Formula:
C19H28O4
Purity:
98.06%
Color and Shape:
Solid
Molecular weight:
320.42
Ref: TM-T12092
| 1mg | 79.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 235.00 € | ||
| 25mg | 398.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 820.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Fluvastatin
CAS:93957-54-1
Fluvastatin (XU-62320) is an HMG-CoA reductase inhibitor used to lower plasma cholesterol levels and prevent …
Formula:
C24H26FNO4
Purity:
98.94%
Color and Shape:
Solid
Molecular weight:
411.47
Ref: TM-T21405
| 10mg | 35.00 € | ||
| 25mg | 52.00 € | ||
| 50mg | 66.00 € | ||
| 100mg | 95.00 € |
Estimated delivery in United States, on Monday 21 Apr 2025
SR12813
CAS:126411-39-0
SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.
Formula:
C24H42O7P2
Purity:
99.43%
Color and Shape:
Solid
Molecular weight:
504.53
Ref: TM-T6994
| 5mg | 55.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 230.00 € | ||
| 100mg | 334.00 € | ||
| 200mg | 538.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Apomine
CAS:126411-13-0
Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂,可在体外促进骨髓瘤细胞的凋亡,并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。
Formula:
C28H52O7P2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
562.66
Ref: TM-T26644
| 1mg | 120.00 € | ||
| 5mg | 264.00 € | ||
| 10mg | 376.00 € | ||
| 25mg | 630.00 € | ||
| 50mg | 880.00 € | ||
| 100mg | 1,169.00 € | ||
| 1mL*10mM (DMSO) | 325.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Clinofibrate
CAS:30299-08-2
Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.
Formula:
C28H36O6
Purity:
99.84%
Color and Shape:
White Crystalline Powder
Molecular weight:
468.58
Ref: TM-T6450
| 5mg | 47.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | 173.00 € | ||
| 100mg | 274.00 € | ||
| 200mg | 406.00 € | ||
| 1mL*10mM (DMSO) | 48.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
7-Ketocholesterol
CAS:566-28-9
7-Ketocholesterol is a metabolite of Cholesterol
Formula:
C27H44O2
Purity:
97.59% - 99.46%
Color and Shape:
Solid
Molecular weight:
400.65
Ref: TM-TN6715
| 5mg | 48.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 156.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Atorvastatin
CAS:134523-00-5
Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up …
Formula:
C33H35FN2O5
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
558.64
Ref: TM-T20765
| 2mg | 34.00 € | ||
| 5mg | 39.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 62.00 € | ||
| 50mg | 71.00 € | ||
| 100mg | 111.00 € | ||
| 500mg | 265.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 2 May 2025
2'-Ethyl Simvastatin
CAS:79902-42-4
2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.
Formula:
C23H34O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
390.51
Ref: TM-T10070
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Crilvastatin
CAS:120551-59-9
Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in …
Formula:
C14H23NO3
Purity:
98.28% - 98.47%
Color and Shape:
Solid
Molecular weight:
253.34
Ref: TM-T25276
| 1mg | 279.00 € | ||
| 5mg | 685.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,444.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,375.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
Dalvastatin
CAS:132100-55-1
Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits …
Formula:
C24H31FO3
Purity:
98.08%
Color and Shape:
Solid
Molecular weight:
386.5
Ref: TM-T25285
| 1mg | 182.00 € | ||
| 5mg | 457.00 € | ||
| 10mg | 652.00 € | ||
| 25mg | 1,026.00 € | ||
| 50mg | 1,406.00 € | ||
| 100mg | 1,890.00 € |
Estimated delivery in United States, on Tuesday 3 Jun 2025
HMG499
CAS:2416941-68-7
HMG499 inhibits HMG-CoA reductase (IC50: 0.41μM), reduces statin-induced HMGCR, lowers cholesterol, and lessens atherosclerosis.
Formula:
C33H54O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
498.78
Ref: TM-T11572
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Tuesday 15 Jul 2025
