HMG-CoA Reductase
HMG-CoA Reductase is a key enzyme in the mevalonate pathway, responsible for the synthesis of cholesterol and other isoprenoids. Inhibitors of HMG-CoA reductase, commonly known as statins, are widely used to lower cholesterol levels and reduce the risk of cardiovascular diseases. These inhibitors also have potential benefits in cancer and neurodegenerative disease research. At CymitQuimica, we provide a variety of HMG-CoA reductase inhibitors to support your research in lipid metabolism, cardiovascular health, and therapeutic development.
Found 34 products of "HMG-CoA Reductase"
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Atorvastatin lactone
CAS:Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.Formula:C33H33FN2O4Purity:98.05% - 98.16%Color and Shape:SolidMolecular weight:540.62L 645164
CAS:L 645164 is an inhibitor of hydroxymethylglutaryl-CoA reductase.Formula:C22H23FO3Color and Shape:SolidMolecular weight:354.41HMG-CoA Reductase-IN-1
HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKmFormula:C27H29N3O7Color and Shape:SolidMolecular weight:507.54(Rac)-5-Keto Fluvastatin
CAS:(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.Formula:C24H24FNO4Purity:95.04%Color and Shape:SolidMolecular weight:409.45Lipid Metabolism Compound Library
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Color and Shape:Odour Solid24,25-Epoxycholesterol
CAS:24,25-Epoxycholesterol is an oxysterol agonist of the liver X receptor, known to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) in hepatic cells. Additionally, 24,25-Epoxycholesterol plays a role in regulating cholesterol metabolism within the liver.Formula:C27H44O2Color and Shape:SolidMolecular weight:400.64(3S,5R)-Fluvastatin D6 sodium
CAS:(3S,5R)-Fluvastatin D6 sodium: deuterium-labeled synthetic HMG-CoA reductase inhibitor with 8 nM IC50.Formula:C24H25FNNaO4Purity:98%Color and Shape:SolidMolecular weight:439.49Rawsonol
CAS:Rawsonol is a HMG-CoA reductase inhibitor from the tropical green alga Avrainvillea rawsoni.Formula:C29H24Br4O7Color and Shape:SolidMolecular weight:804.11Ganoderenic acid K
CAS:Ganoderenic acid K, from Ganoderma lucidum, inhibits HMG-CoA reductase with an IC50 of 16.5 μM.Formula:C32H44O9Color and Shape:SolidMolecular weight:572.69Pravastatin lactone
CAS:Pravastatin lactone, a non-enzymatic stomach derivative of pravastatin, inhibits HMG-CoA reductase and stems from mevastatin.
Formula:C23H34O6Color and Shape:SolidMolecular weight:406.519Atorvastatin calcium trihydrate
CAS:Atorvastatin is used to inhibits HMG-CoA reductase for lowering blood cholesterol and for prevention of events associated with cardiovascular disease.Formula:C66H74CaF2N4O13Color and Shape:SolidMolecular weight:1209.39Rosuvastatin Sodium
CAS:Rosuvastatin Sodium (ZD4522 Sodium) is a competitive HMG-CoA reductase (HMGCR) inhibitor (IC50=11 nM) with lipid-lowering and anti-atherosclerotic effects.Formula:C22H27FN3NaO6SColor and Shape:SolidMolecular weight:503.52PPD 10558
CAS:PPD 10558, a HMG-CoA reductase inhibitor, is used potentially for treatment of primary hypercholesterolemia.Formula:C34H37FN2O6Color and Shape:SolidMolecular weight:588.67Fluvastatin potassium
CAS:Fluvastatin, a synthetic statin, lowers cholesterol and prevents heart disease.Formula:C24H25FKNO4Color and Shape:SolidMolecular weight:449.567-Ketocholesterol
CAS:7-Ketocholesterol is a metabolite of CholesterolFormula:C27H44O2Purity:97.59% - 98.84%Color and Shape:SolidMolecular weight:400.65Simvastatin acid ammonium
CAS:Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor.Formula:C25H43NO6Purity:98.3%Color and Shape:SolidMolecular weight:453.61Tenivastatin
CAS:Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor used in the study of primary hyperlipidemia.Formula:C25H40O6Purity:99.56%Color and Shape:SolidMolecular weight:436.58Pravastatin
CAS:Pravastatin (CS-514) is a competitive HMG-CoA reductase inhibitor with an IC50 of 5.6 μM for sterol synthesis, capable of lowering serum cholesterol.Formula:C23H36O7Purity:99.99%Color and Shape:White PowderMolecular weight:424.534-Acetylsimvastatin
CAS:4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).Formula:C27H40O6Purity:98%Color and Shape:SolidMolecular weight:460.6Crilvastatin
CAS:Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.Formula:C14H23NO3Purity:98.69% - 99.54%Color and Shape:SolidMolecular weight:253.34
