HMG-CoA Reductase
HMG-CoA Reductase is a key enzyme in the mevalonate pathway, responsible for the synthesis of cholesterol and other isoprenoids. Inhibitors of HMG-CoA reductase, commonly known as statins, are widely used to lower cholesterol levels and reduce the risk of cardiovascular diseases. These inhibitors also have potential benefits in cancer and neurodegenerative disease research. At CymitQuimica, we provide a variety of HMG-CoA reductase inhibitors to support your research in lipid metabolism, cardiovascular health, and therapeutic development.
Found 36 products of "HMG-CoA Reductase"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Atorvastatin lactone
CAS:Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.Formula:C33H33FN2O4Purity:98.05% - 98.16%Color and Shape:SolidMolecular weight:540.62Lipid Metabolism Compound Library
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Color and Shape:Odour SolidDim16 HCl
CAS:Dim16 HCl is a dual PCSK9 and HMG-CoA reductase inhibitor that enhances LDL uptake, supporting lipid metabolism and cardiovascular research.Formula:C29H39ClIN5Purity:99.07% - 99.14%Color and Shape:SoildMolecular weight:620.0124,25-Epoxycholesterol
CAS:24,25-Epoxycholesterol is an oxysterol agonist of the liver X receptor, known to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) in hepatic cells. Additionally, 24,25-Epoxycholesterol plays a role in regulating cholesterol metabolism within the liver.Formula:C27H44O2Color and Shape:SolidMolecular weight:400.64L 645164
CAS:L 645164 is an inhibitor of hydroxymethylglutaryl-CoA reductase.Formula:C22H23FO3Color and Shape:SolidMolecular weight:354.41HMG-CoA Reductase-IN-1
HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKmFormula:C27H29N3O7Color and Shape:SolidMolecular weight:507.54Ganoderenic acid K
CAS:Ganoderenic acid K, from Ganoderma lucidum, inhibits HMG-CoA reductase with an IC50 of 16.5 μM.Formula:C32H44O9Color and Shape:SolidMolecular weight:572.69Rawsonol
CAS:Rawsonol is a HMG-CoA reductase inhibitor from the tropical green alga Avrainvillea rawsoni.Formula:C29H24Br4O7Color and Shape:SolidMolecular weight:804.11(3S,5R)-Fluvastatin D6 sodium
CAS:(3S,5R)-Fluvastatin D6 sodium: deuterium-labeled synthetic HMG-CoA reductase inhibitor with 8 nM IC50.Formula:C24H25FNNaO4Purity:98%Color and Shape:SolidMolecular weight:439.49(Rac)-5-Keto Fluvastatin
CAS:(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.Formula:C24H24FNO4Purity:95.04%Color and Shape:SolidMolecular weight:409.45Rosuvastatin Sodium
CAS:Rosuvastatin Sodium (ZD4522 Sodium) is a competitive HMG-CoA reductase (HMGCR) inhibitor (IC50=11 nM) with lipid-lowering and anti-atherosclerotic effects.Formula:C22H27FN3NaO6SColor and Shape:SolidMolecular weight:503.52Pravastatin lactone
CAS:Pravastatin lactone, a non-enzymatic stomach derivative of pravastatin, inhibits HMG-CoA reductase and stems from mevastatin.
Formula:C23H34O6Color and Shape:SolidMolecular weight:406.519PPD 10558
CAS:PPD 10558, a HMG-CoA reductase inhibitor, is used potentially for treatment of primary hypercholesterolemia.Formula:C34H37FN2O6Color and Shape:SolidMolecular weight:588.67Lovastatin hydroxy acid sodium (Standard)
CAS:Lovastatin hydroxy acid sodium (Standard) is the standard substance of Lovastatin hydroxy acid sodium, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Lovastatin Sodium is an HMG-CoA reductase inhibitor.Formula:C24H37NaO6Color and Shape:SolidMolecular weight:444.54Atorvastatin calcium trihydrate
CAS:Atorvastatin is used to inhibits HMG-CoA reductase for lowering blood cholesterol and for prevention of events associated with cardiovascular disease.Formula:C66H74CaF2N4O13Color and Shape:SolidMolecular weight:1209.39Fluvastatin potassium
CAS:Fluvastatin, a synthetic statin, lowers cholesterol and prevents heart disease.Formula:C24H25FKNO4Color and Shape:SolidMolecular weight:449.567-Ketocholesterol
CAS:7-Ketocholesterol is a metabolite of CholesterolFormula:C27H44O2Purity:97.59% - 98.84%Color and Shape:SolidMolecular weight:400.65Simvastatin acid ammonium
CAS:Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor.Formula:C25H43NO6Purity:98.3%Color and Shape:SolidMolecular weight:453.61Tenivastatin
CAS:Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor used in the study of primary hyperlipidemia.Formula:C25H40O6Purity:99.56%Color and Shape:SolidMolecular weight:436.58Pravastatin
CAS:Pravastatin (CS-514) is a competitive HMG-CoA reductase inhibitor with an IC50 of 5.6 μM for sterol synthesis, capable of lowering serum cholesterol.Formula:C23H36O7Purity:99.99%Color and Shape:White PowderMolecular weight:424.53(3S,5R)-Fluvastatin sodium
CAS:(3S,5R)-Fluvastatin sodium: synthetic HMG-CoA reductase inhibitor, IC50 8 nM, boosts vascular cell antioxidant defense.Formula:C24H26FNNaO4Purity:99.39%Color and Shape:SolidMolecular weight:434.463(Z)-Pitavastatin calcium
CAS:(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent of hydroxymethylglutaryl-CoA (HMG-CoA) reductase.Formula:C50H50CaF2N2O8Purity:98%Color and Shape:SolidMolecular weight:885.031L 669262
CAS:L 669262 is a potent inhibitor of HMG-CoA reductase.Formula:C25H36O6Color and Shape:SolidMolecular weight:432.55(3S,5R)-Pitavastatin calcium
CAS:(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Formula:C25H26CaFNO4Purity:98%Color and Shape:SolidMolecular weight:463.5624-Acetylsimvastatin
CAS:4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).Formula:C27H40O6Purity:98%Color and Shape:SolidMolecular weight:460.6Lovastatin hydroxy acid sodium
CAS:Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.6 nM, which can lower cholesterol.Formula:C24H37NaO6Purity:99.92%Color and Shape:SolidMolecular weight:444.54Crilvastatin
CAS:Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.Formula:C14H23NO3Purity:98.69% - 99.54%Color and Shape:SolidMolecular weight:253.34Simvastatin acid calcium hydrate
CAS:Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.Formula:C25H40O6Color and Shape:SolidMolecular weight:436.282492'-Ethyl Simvastatin
CAS:2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.Formula:C23H34O5Purity:98%Color and Shape:SolidMolecular weight:390.51(3S,5S)-Pitavastatin calcium
CAS:(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Formula:C25H26CaFNO4Purity:98%Color and Shape:SolidMolecular weight:463.562Dalvastatin
CAS:Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepaticFormula:C24H31FO3Purity:98.07%Color and Shape:SolidMolecular weight:386.5(3R,5R)-Rosuvastatin calcium
CAS:(3R,5R)-Rosuvastatin, a potential impurity detected in bulk rosuvastatin formulations, arises as a degradation product through various stresses including acid or base hydrolysis, thermal, photolytic, hydrolytic, oxidative stress, or during storage. This compound is associated with the HMG-CoA reductase inhibitor class to which rosuvastatin belongs.Formula:C22H28FN3O6SCaColor and Shape:SolidMolecular weight:500.6Rosuvastatin zinc salt
CAS:Rosuvastatin zinc salt (Rosuvastatin zinc), a zinc-infused variant of Rosuvastatin, functions as an HMG-CoA reductase inhibitor, utilized primarily inFormula:C44H54F2N6O12S2ZnColor and Shape:SolidMolecular weight:1026.47QH536
CAS:QH536 degrades HMGCR (EC50: 0.22 μM), has anti-inflammatory properties, and avoids cholesterol buildup; useful for cardiovascular and NASH research.Formula:C33H49N3O3Color and Shape:SolidMolecular weight:535.76Bemfivastatin hemicalcium
CAS:Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.Formula:C34H36FN2O6CaColor and Shape:SolidMolecular weight:607.67L 668411
CAS:L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.Formula:C19H30O5Purity:98%Color and Shape:SolidMolecular weight:338.44
