HMG-CoA Reductase
HMG-CoA Reductase is a key enzyme in the mevalonate pathway, responsible for the synthesis of cholesterol and other isoprenoids. Inhibitors of HMG-CoA reductase, commonly known as statins, are widely used to lower cholesterol levels and reduce the risk of cardiovascular diseases. These inhibitors also have potential benefits in cancer and neurodegenerative disease research. At CymitQuimica, we provide a variety of HMG-CoA reductase inhibitors to support your research in lipid metabolism, cardiovascular health, and therapeutic development.
Found 36 products of "HMG-CoA Reductase"
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(3S,5R)-Fluvastatin sodium
CAS:(3S,5R)-Fluvastatin sodium: synthetic HMG-CoA reductase inhibitor, IC50 8 nM, boosts vascular cell antioxidant defense.Formula:C24H26FNNaO4Purity:99.39%Color and Shape:SolidMolecular weight:434.463(Z)-Pitavastatin calcium
CAS:(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent of hydroxymethylglutaryl-CoA (HMG-CoA) reductase.Formula:C50H50CaF2N2O8Purity:98%Color and Shape:SolidMolecular weight:885.031L 669262
CAS:L 669262 is a potent inhibitor of HMG-CoA reductase.Formula:C25H36O6Color and Shape:SolidMolecular weight:432.55(3S,5R)-Pitavastatin calcium
CAS:(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Formula:C25H26CaFNO4Purity:98%Color and Shape:SolidMolecular weight:463.5624-Acetylsimvastatin
CAS:4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).Formula:C27H40O6Purity:98%Color and Shape:SolidMolecular weight:460.6Lovastatin hydroxy acid sodium
CAS:Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.6 nM, which can lower cholesterol.Formula:C24H37NaO6Purity:99.92%Color and Shape:SolidMolecular weight:444.54Crilvastatin
CAS:Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.Formula:C14H23NO3Purity:98.69% - 99.54%Color and Shape:SolidMolecular weight:253.34Simvastatin acid calcium hydrate
CAS:Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.Formula:C25H40O6Color and Shape:SolidMolecular weight:436.282492'-Ethyl Simvastatin
CAS:2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.Formula:C23H34O5Purity:98%Color and Shape:SolidMolecular weight:390.51(3S,5S)-Pitavastatin calcium
CAS:(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Formula:C25H26CaFNO4Purity:98%Color and Shape:SolidMolecular weight:463.562Dalvastatin
CAS:Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepaticFormula:C24H31FO3Purity:98.07%Color and Shape:SolidMolecular weight:386.5(3R,5R)-Rosuvastatin calcium
CAS:(3R,5R)-Rosuvastatin, a potential impurity detected in bulk rosuvastatin formulations, arises as a degradation product through various stresses including acid or base hydrolysis, thermal, photolytic, hydrolytic, oxidative stress, or during storage. This compound is associated with the HMG-CoA reductase inhibitor class to which rosuvastatin belongs.Formula:C22H28FN3O6SCaColor and Shape:SolidMolecular weight:500.6Rosuvastatin zinc salt
CAS:Rosuvastatin zinc salt (Rosuvastatin zinc), a zinc-infused variant of Rosuvastatin, functions as an HMG-CoA reductase inhibitor, utilized primarily inFormula:C44H54F2N6O12S2ZnColor and Shape:SolidMolecular weight:1026.47QH536
CAS:QH536 degrades HMGCR (EC50: 0.22 μM), has anti-inflammatory properties, and avoids cholesterol buildup; useful for cardiovascular and NASH research.Formula:C33H49N3O3Color and Shape:SolidMolecular weight:535.76Bemfivastatin hemicalcium
CAS:Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.Formula:C34H36FN2O6CaColor and Shape:SolidMolecular weight:607.67L 668411
CAS:L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.Formula:C19H30O5Purity:98%Color and Shape:SolidMolecular weight:338.44
