Dehydrogenase
Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.
Found 267 products of "Dehydrogenase"
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PDK-IN-1
CAS:<p>PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.</p>Formula:C20H16BrN7OColor and Shape:SolidMolecular weight:450.29MCI-INI-3
CAS:<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Formula:C21H15N3O4Color and Shape:SolidMolecular weight:373.36BMS-770767
CAS:<p>BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.</p>Formula:C19H18ClN3O2Color and Shape:SolidMolecular weight:355.82SW209049
CAS:<p>SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.</p>Formula:C25H18N2O4SPurity:99.72%Color and Shape:SolidMolecular weight:442.49DSM1465
<p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>Formula:C17H12ClF6N5O2Color and Shape:SolidMolecular weight:467.75317β-HSD10-IN-1
CAS:<p>17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.</p>Formula:C16H13ClN4O3SPurity:98.47%Color and Shape:SoildMolecular weight:376.82Osmanthuside H
CAS:<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Formula:C19H28O11Color and Shape:SolidMolecular weight:432.422PDK-IN-2
<p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>Formula:C17H23AsCl2N2O2S2Color and Shape:SolidMolecular weight:497.33MTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Formula:C26H21F6N2O5Color and Shape:SolidMolecular weight:555.45Diethanolamine hydrochloride
CAS:<p>Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.</p>Formula:C4H12ClNO2Purity:99.69%Color and Shape:SolidMolecular weight:141.6D-Lactate dehydrogenase
CAS:<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Color and Shape:SolidhDHODH-IN-13
CAS:<p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>Color and Shape:SoildOctanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Formula:C29H49N7NaO17P3SColor and Shape:SolidMolecular weight:915.7111β-HSD1 inibitor 19
CAS:<p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>Formula:C19H16ClF4N3O2SPurity:99.58%Color and Shape:SoildMolecular weight:461.86MTHFD2-IN-4 sodium
<p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>Formula:C26H21F6N2NaO5Color and Shape:SolidMolecular weight:578.44DHODH-IN-23
CAS:<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Formula:C24H21ClFNO4Purity:99.7%Color and Shape:SolidMolecular weight:441.88DHODH-IN-16
CAS:<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Formula:C24H25FN4O3Purity:99.64%Color and Shape:SolidMolecular weight:436.48Antiproliferative agent-13
CAS:<p>Antiproliferative agent-13 is a compound with antiproliferative activity.</p>Formula:C20H18N2O6Purity:99.723%Color and Shape:SolidMolecular weight:382.37DSM705
CAS:<p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>Formula:C19H19F3N6OColor and Shape:SolidMolecular weight:404.397Aldehyde dehydrogenase (NAD(P))
CAS:<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Color and Shape:SolidALDH1A2-IN-1
CAS:<p>ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.</p>Formula:C21H26N4O4SPurity:99.51%Color and Shape:SolidMolecular weight:430.52Ketogestin
CAS:<p>Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.</p>Formula:C21H28O3Purity:99.19%Color and Shape:SolidMolecular weight:328.45PKUMDL-WQ-2201
CAS:<p>PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.</p>Formula:C15H14ClN3O3SColor and Shape:SolidMolecular weight:351.81DSM265
CAS:<p>DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.</p>Formula:C14H12F7N5SPurity:99.79%Color and Shape:SolidMolecular weight:415.332-Bromoacetamide
CAS:<p>2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.</p>Formula:C2H4BrNOPurity:99.83%Color and Shape:SolidMolecular weight:137.96ALDH1A3-IN-1
CAS:<p>ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].</p>Formula:C13H18BrNOColor and Shape:SolidMolecular weight:284.19DSM502
CAS:<p>DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.</p>Formula:C16H16F3N3OPurity:99.52%Color and Shape:SolidMolecular weight:323.31ALDH3A1-IN-1
CAS:<p>ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.</p>Formula:C13H18N2O3Purity:99.86%Color and Shape:SolidMolecular weight:250.29ABT-384
CAS:<p>ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.</p>Formula:C25H34F3N5O2Purity:99.863%Color and Shape:SolidMolecular weight:493.584-Isopropoxybenzaldehyde
CAS:<p>ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.</p>Formula:C10H12O2Purity:99.00%Color and Shape:SolidMolecular weight:164.2Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Formula:C23H15F2NO2Purity:99.1% - 99.57%Color and Shape:SolidMolecular weight:375.37BVT 2733
CAS:<p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>Formula:C17H21ClN4O3S2Purity:98% - 99.64%Color and Shape:SolidMolecular weight:428.96Vidofludimus hemicalcium
CAS:Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Formula:C20H18FNO4CaColor and Shape:SolidMolecular weight:375.4AGI-6780
CAS:<p>AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.</p>Formula:C21H18F3N3O3S2Purity:98.19% - 99.7%Color and Shape:SolidMolecular weight:481.51Mutant IDH1-IN-1
CAS:<p>Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.</p>Formula:C30H31FN4O2Purity:99.49% - >99.99%Color and Shape:SolidMolecular weight:498.59(E/Z)-Teriflunomide
CAS:<p>(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.</p>Formula:C12H9F3N2O2Purity:99.49% - 99.76%Color and Shape:White SolidMolecular weight:270.21Nitrofurazone
CAS:<p>Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.</p>Formula:C6H6N4O4Purity:99.87%Color and Shape:Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)Molecular weight:198.14NCT-503
CAS:<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Formula:C20H23F3N4SPurity:98.91% - 99.84%Color and Shape:SolidMolecular weight:408.48L-Allylglycine
CAS:<p>L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.</p>Formula:C5H9NO2Purity:≥98%Color and Shape:White To Off-White Crystalline PowderMolecular weight:115.13R162
CAS:<p>R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.</p>Formula:C17H12O3Purity:96.21% - 98.15%Color and Shape:SolidMolecular weight:264.28PfDHODH-IN-2
CAS:<p>PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.</p>Formula:C13H12ClNO3SPurity:98.9%Color and Shape:SolidMolecular weight:297.76VER-246608
CAS:<p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>Formula:C28H23ClF2N4O4Purity:98.5%Color and Shape:SolidMolecular weight:552.96NCT-505
CAS:<p>NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with</p>Formula:C27H28FN5O3SPurity:99.93%Color and Shape:SolidMolecular weight:521.61BI-187004
CAS:<p>BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.</p>Formula:C21H18N4OPurity:98.63%Color and Shape:SolidMolecular weight:342.39NCT-501 hydrochloride
CAS:<p>NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.</p>Formula:C21H33ClN6O3Color and Shape:SolidMolecular weight:452.98Galloflavin
CAS:<p>Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.</p>Formula:C12H6O8Purity:96.24% - 97.47%Color and Shape:SolidMolecular weight:278.17CM10
CAS:<p>CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.</p>Formula:C20H23N3OPurity:99.84%Color and Shape:SolidMolecular weight:321.42DS-1001b
CAS:<p>DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)</p>Formula:C29H29Cl3FN3O4Purity:99.81%Color and Shape:SolidMolecular weight:608.92Perfluorooctanoic acid
CAS:<p>Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.</p>Formula:C8HF15O2Purity:99.70%Color and Shape:White To Off-White Powder OthersolidMolecular weight:414.07G6PDi-1
CAS:<p>G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.</p>Formula:C14H12N4OSPurity:98.69%Color and Shape:SolidMolecular weight:284.34
