Dehydrogenase
Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.
Found 271 products of "Dehydrogenase"
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TM-1
CAS:<p>TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.</p>Formula:C26H32N2O6Color and Shape:SolidMolecular weight:468.54DHODH-IN-3
CAS:<p>DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.</p>Formula:C17H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:312.75ALDH3A1-IN-2
CAS:<p>ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.</p>Formula:C11H14N2O3Color and Shape:SolidMolecular weight:222.24hDHODH-IN-5
CAS:<p>hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).</p>Formula:C21H21F3N2O2Purity:99.55%Color and Shape:SolidMolecular weight:390.4ML387
CAS:<p>ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>Formula:C20H21N3O2Purity:98%Color and Shape:SolidMolecular weight:335.4ALDH1A1-IN-3
CAS:<p>ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.</p>Formula:C31H36F3N5O4Color and Shape:SolidMolecular weight:599.6411β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Formula:C13H9F3N2OColor and Shape:SolidMolecular weight:266.22ML-148
CAS:<p>ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).</p>Formula:C20H21N3OPurity:99.88%Color and Shape:SolidMolecular weight:319.4DHODH-IN-21
CAS:<p>DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.</p>Formula:C20H19ClF4N6O4Color and Shape:SolidMolecular weight:518.85p-Valerylphenol
CAS:p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.Formula:C11H14O2Purity:99.87%Color and Shape:White To Light Beige PowderMolecular weight:178.23BRD9185
CAS:<p>BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.</p>Formula:C23H21F6N3O2Purity:98%Color and Shape:SolidMolecular weight:485.42Oxycinchophen
CAS:<p>Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.</p>Formula:C16H11NO3Purity:98%Color and Shape:SolidMolecular weight:265.26P1788
CAS:<p>P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].</p>Formula:C15H17NO3Color and Shape:SolidMolecular weight:259.3DHODH-IN-8
CAS:<p>DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).</p>Formula:C17H13ClN2O2Purity:99.78%Color and Shape:SolidMolecular weight:312.75GW648495
CAS:<p>GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.</p>Formula:C16H13N5Purity:98%Color and Shape:SolidMolecular weight:275.31BVT-116429
CAS:<p>BVT-116429 is an inhibitor of 11β-HSD1.</p>Formula:C13H12F4N2OSPurity:98%Color and Shape:SolidMolecular weight:320.31KM04416
CAS:<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Formula:C12H11NO3SPurity:99.88%Color and Shape:SolidMolecular weight:249.29UCK2 Inhibitor-2
CAS:<p>UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.</p>Formula:C28H23N3O4SPurity:98.76% - 99.25%Color and Shape:SolidMolecular weight:497.57DHODH-IN-4
CAS:<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Formula:C17H12Cl2N2O2Purity:99.34%Color and Shape:SolidMolecular weight:347.2M77976
CAS:<p>M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.</p>Formula:C17H16N2O3Purity:99.43%Color and Shape:SolidMolecular weight:296.32
