Dehydrogenase
Dehydrogenases are enzymes involved in the oxidation-reduction reactions of metabolic pathways, playing a central role in energy production and cellular respiration. These enzymes are crucial for processes such as the citric acid cycle, glycolysis, and fatty acid oxidation. Dehydrogenase inhibitors are important tools in the study of metabolic diseases, cancer, and oxidative stress. At CymitQuimica, we provide a comprehensive selection of dehydrogenase inhibitors to support your research in metabolism, cancer biology, and biochemistry.
Found 271 products of "Dehydrogenase"
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673-A
CAS:<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formula:C15H13NOColor and Shape:SolidMolecular weight:223.27SCH-451659
CAS:<p>SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.</p>Formula:C30H39Cl2N3O2Purity:98%Color and Shape:SolidMolecular weight:544.56DHODH-IN-12
CAS:<p>DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.</p>Formula:C10H9N3O2Purity:99.53%Color and Shape:SolidMolecular weight:203.2Laflunimus
CAS:<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Formula:C15H13F3N2O2Purity:99.86%Color and Shape:SolidMolecular weight:310.27CM39
CAS:<p>CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.</p>Formula:C19H15FN4OSColor and Shape:SolidMolecular weight:366.41Nitrefazole
CAS:<p>Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.</p>Formula:C10H8N4O4Color and Shape:SolidMolecular weight:248.1911β-HSD1-IN-6
CAS:<p>11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).</p>Formula:C21H19ClN4OColor and Shape:SolidMolecular weight:378.86ALDH1A1-IN-2
CAS:<p>ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity</p>Formula:C25H23ClN4O3SPurity:99.48%Color and Shape:SolidMolecular weight:494.99AZD8329
CAS:<p>AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.</p>Formula:C25H31N3O3Purity:99.31%Color and Shape:SolidMolecular weight:421.53MEDS433
CAS:<p>MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.</p>Formula:C20H11F4N3O2Color and Shape:SolidMolecular weight:401.31hDHODH-IN-11
CAS:<p>hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.</p>Formula:C24H23N3O3Color and Shape:SolidMolecular weight:401.46CM026
CAS:<p>CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.</p>Formula:C22H30N6O4Color and Shape:SolidMolecular weight:442.51hDHODH-IN-4
CAS:hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.Formula:C21H24N4O2Purity:99.87%Color and Shape:SolidMolecular weight:364.44AMG-221
CAS:<p>AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.</p>Formula:C14H22N2OSPurity:98%Color and Shape:SolidMolecular weight:266.4DHODH-IN-17
CAS:<p>DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.</p>Formula:C12H9ClN2O2Purity:99.41% - 99.52%Color and Shape:SolidMolecular weight:248.6711β-HSD1-IN-10
CAS:<p>11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitive</p>Formula:C16H10F3NO2Color and Shape:SolidMolecular weight:305.25DHODH-IN-20
CAS:<p>Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.</p>Formula:C24H25F4N3O3Color and Shape:SolidMolecular weight:479.47DHODH-IN-19
CAS:<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Formula:C22H18ClF6N3O3Color and Shape:SolidMolecular weight:521.84ASP3662
CAS:<p>ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.</p>Formula:C19H16ClF3N4O2Color and Shape:SolidMolecular weight:424.811β-HSD1-IN-1
CAS:<p>11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.</p>Formula:C18H14ClF4N3OPurity:99.84%Color and Shape:SolidMolecular weight:399.77
