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Lipoxygenase

Lipoxygenase

Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.

Found 151 products for "Lipoxygenase".

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  • PXS-6302 hydrochloride
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    PXS-6302 hydrochloride

    CAS:
    PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3
    Formula:C10H11ClF3NO2S
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:301.71

    Ref: TM-T60438L

  • 5-LOX/MAOs-IN-1
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    5-LOX/MAOs-IN-1

    CAS:
    Compound 3, known as 5-LOX/MAOs-IN-1, acts as an inhibitor of 5-LOX/MAOs and is an effective free radical scavenger, displaying antioxidant characteristics. It has demonstrated neuroprotective effects in cell models damaged by oxidative stress and is capable of activating the neurogenesis microenvironment in adult mouse neural stem cells. This compound is utilized in research focused on neurodegenerative diseases.
    Formula:C18H18N2O2
    Color and Shape:Solid
    Molecular weight:294.35

    Ref: TM-T200298

  • AZD 4407
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    AZD 4407

    CAS:
    AZD 4407 is a potent inhibitor of 5-lipoxygenase.
    Formula:C19H21NO3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:375.5

    Ref: TM-T10438

  • WY-50295
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    WY-50295

    CAS:
    WY-50295 is an orally active and selective 5-lipoxygenase inhibitor. In rat whole blood leukocytes, WY-50295 inhibits LTB4 formation with an IC50 of 40 μM and an oral ED50 of 18 mg/kg. WY-50295 is applicable for research into asthma and other leukotriene-dependent conditions.
    Formula:C23H19NO3
    Color and Shape:Solid
    Molecular weight:357.40

    Ref: TM-T210933

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    ALOX15-IN-1

    ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.
    Formula:C24H31N3O5S
    Color and Shape:Solid
    Molecular weight:473.59

    Ref: TM-T63075

  • NCTT-956
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    NCTT-956

    CAS:
    NCTT-956 is a potent and specific inhibitor of platelet 12-lipoxygenase (12-LOX) activity.
    Formula:C17H15N3O4S
    Molecular weight:357.384

    Ref: TM-T204770

  • L 691816
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    L 691816

    CAS:
    L 691816 is an effective inhibitor of the 5-LO reaction.
    Formula:C36H35ClN6OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:635.22

    Ref: TM-T24341

  • Lobaric acid
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    Lobaric acid

    CAS:
    Lobaric acid, from Stereocaulon lichen, has antioxidant and anticancer properties, inhibits PTP1B and 12(S)-LOX, and reduces TMV lesions in plants.
    Formula:C25H28O8
    Color and Shape:Solid
    Molecular weight:456.48

    Ref: TM-T71811

  • Resolvin E2
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    Resolvin E2

    CAS:
    RvE2, a bioactive lipid from the SPM family, is made from EPA and reduces inflammatory neutrophil infiltration and helps treat NAFLD and other diseases.
    Formula:C20H30O4
    Color and Shape:Solid
    Molecular weight:334.45

    Ref: TM-T35881

  • h15-LOX-2 inhibitor 3
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    h15-LOX-2 inhibitor 3

    CAS:
    Compound 13, identified as h15-LOX-2 inhibitor 3, exhibits inhibitory activity against h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively.
    Formula:C22H13N5O3
    Color and Shape:Solid
    Molecular weight:395.37

    Ref: TM-T200110

  • ALOX15-IN-2
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    ALOX15-IN-2

    CAS:
    ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.
    Formula:C23H29N3O4S
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:443.559

    Ref: TM-T62606