Lipoxygenase
Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.
Found 133 products of "Lipoxygenase"
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2-TEDC
CAS:2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.Formula:C16H13NO4SPurity:99.97%Color and Shape:SolidMolecular weight:315.34LY 269415
CAS:LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.Formula:C19H28N2O2SColor and Shape:SolidMolecular weight:348.5Butibufen
CAS:Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.Formula:C14H20O2Purity:98.11% - 98.91%Color and Shape:SolidMolecular weight:220.315-LOX-IN-1
CAS:5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.
Formula:C20H18N2O2SPurity:97.45%Color and Shape:SolidMolecular weight:350.43A-69412
CAS:A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.Formula:C7H10N2O3Purity:99.54%Color and Shape:SolidMolecular weight:170.17Ref: TM-T10208
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€500mg2,147.00€1mL*10mM (DMSO)188.00€Lonapalene
CAS:Lonapalene is a topically effective inhibitor of 5-lipoxygenase.Formula:C16H15ClO6Purity:98.67% - 99.33%Color and Shape:SolidMolecular weight:338.74Ref: TM-T16802
1mg100.00€2mg160.00€5mg290.00€10mg424.00€25mg642.00€50mg858.00€100mg1,153.00€200mg1,558.00€1mL*10mM (DMSO)318.00€A 78773
CAS:A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.Formula:C15H13FN2O4Color and Shape:SolidMolecular weight:304.27MLS000545091
CAS:MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.Formula:C14H15ClN2OPurity:99.84%Color and Shape:SolidMolecular weight:262.731-Stearoyl-2-Oleoyl-3-Linoleoyl-rac-glycerol
CAS:1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol is a triacylglycerol consisting of stearic acid, oleic acid, and linoleic acid esterified at the sn-1, sn-2, and sn-3 positions, respectively. This compound is present in peanut and soybean oils as well as in ostrich and emu oils. Additionally, it serves as a substrate for soybean lipoxygenase in cell-free assays.Formula:C57H104O6Color and Shape:SolidMolecular weight:885.4317(S)-HpDHA
CAS:17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].Formula:C22H32O4Color and Shape:SolidMolecular weight:360.49CMI-392
CAS:CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).Formula:C31H37ClN2O8SPurity:98%Color and Shape:SolidMolecular weight:633.1515(S)-HEDE
CAS:15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 μM.Formula:C20H36O3Color and Shape:SolidMolecular weight:324.5Benoxaprofen
CAS:Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.Formula:C16H12ClNO3Purity:98.87%Color and Shape:SolidMolecular weight:301.72Ref: TM-T19679
1mg202.00€5mg472.00€10mg707.00€25mg1,035.00€50mg1,311.00€100mg1,663.00€1mL*10mM (DMSO)469.00€TA-270
CAS:TA-720, a 5-lipoxygenase inhibitor, is used potentially for the treatment of asthma.Formula:C29H36N2O7Color and Shape:SolidMolecular weight:524.61L 670630
CAS:L 670630 is a potent and orally active 5-lipoxygenase inhibitor.Formula:C25H26O3Purity:98%Color and Shape:SolidMolecular weight:374.47A 79175
CAS:A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.Formula:C15H13FN2O4Purity:98%Color and Shape:SolidMolecular weight:304.275-Lipoxygenase-In-1
CAS:5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.Formula:C23H28N4O2SColor and Shape:SolidMolecular weight:424.56h15-LOX-2 inhibitor 1
CAS:Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].Formula:C17H13F3N2SPurity:98%Color and Shape:SolidMolecular weight:334.36(2E,9Z)-Octadeca-2,9-dienoic acid
CAS:(2E,9Z)-Octadeca-2,9-dienoic acid, a polyunsaturated fatty acid, is utilized in the study of lipoxygenase-dependent metabolism [1].Formula:C18H32O2Color and Shape:SolidMolecular weight:280.455,6-dehydro Arachidonic Acid
CAS:5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.Formula:C20H30O2Color and Shape:SolidMolecular weight:302.45
