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Lipoxygenase

Lipoxygenase

Lipoxygenases are a family of enzymes that catalyze the oxygenation of polyunsaturated fatty acids, leading to the production of bioactive lipid mediators such as leukotrienes and lipoxins. These mediators play critical roles in inflammation, immune responses, and cancer. Inhibitors of lipoxygenase are used to study their role in inflammatory diseases, asthma, and cancer. At CymitQuimica, we provide a variety of lipoxygenase inhibitors to support your research in inflammation, oncology, and lipid metabolism.

Found 124 products of "Lipoxygenase"

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  • Lonapalene
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    Lonapalene

    CAS:
    <p>Lonapalene is a topically effective inhibitor of 5-lipoxygenase.</p>
    Formula:C16H15ClO6
    Purity:98.67% - 99.33%
    Color and Shape:Solid
    Molecular weight:338.74

    Ref: TM-T16802

  • S-2474
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    S-2474

    CAS:
    <p>S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities, and inhibits cell death.</p>
    Formula:C20H31NO3S
    Purity:99.03%
    Color and Shape:Solid
    Molecular weight:365.53

    Ref: TM-T16817

  • 5-LOX-IN-1
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    5-LOX-IN-1

    CAS:
    <p>5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.</p>
    Formula:C20H18N2O2S
    Purity:97.45%
    Color and Shape:Solid
    Molecular weight:350.43

    Ref: TM-T61211

  • h15-LOX-2 inhibitor 1
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    h15-LOX-2 inhibitor 1

    CAS:
    <p>Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].</p>
    Formula:C17H13F3N2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:334.36

    Ref: TM-T79158

  • 5,6-dehydro Arachidonic Acid
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    5,6-dehydro Arachidonic Acid

    CAS:
    <p>5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.</p>
    Formula:C20H30O2
    Color and Shape:Solid
    Molecular weight:302.45

    Ref: TM-T38067

  • A 78773
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    A 78773

    CAS:
    <p>A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.</p>
    Formula:C15H13FN2O4
    Color and Shape:Solid
    Molecular weight:304.27

    Ref: TM-T26447

  • L 670630
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    L 670630

    CAS:
    <p>L 670630 is a potent and orally active 5-lipoxygenase inhibitor.</p>
    Formula:C25H26O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:374.47

    Ref: TM-T24325

  • AA 863
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    AA 863

    CAS:
    <p>AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.</p>
    Formula:C21H26O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:358.43

    Ref: TM-T26493

  • A 79175
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    A 79175

    CAS:
    <p>A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.</p>
    Formula:C15H13FN2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:304.27

    Ref: TM-T26448

  • CMI-392
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    CMI-392

    CAS:
    <p>CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).</p>
    Formula:C31H37ClN2O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:633.15

    Ref: TM-T10844

  • MLS000545091
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    MLS000545091

    CAS:
    <p>MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.</p>
    Formula:C14H15ClN2O
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:262.73

    Ref: TM-T24488

  • Benoxaprofen
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    Benoxaprofen

    CAS:
    <p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>
    Formula:C16H12ClNO3
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:301.72

    Ref: TM-T19679

  • 5-Lipoxygenase-In-1
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    5-Lipoxygenase-In-1

    CAS:
    <p>5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.</p>
    Formula:C23H28N4O2S
    Color and Shape:Solid
    Molecular weight:424.56

    Ref: TM-T10151

  • 17(S)-HpDHA
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    17(S)-HpDHA

    CAS:
    <p>17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].</p>
    Formula:C22H32O4
    Color and Shape:Solid
    Molecular weight:360.49

    Ref: TM-T84487

  • CCT365623
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    CCT365623

    CAS:
    <p>CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.</p>
    Formula:C18H17NO4S3
    Purity:97.299% - 99.49%
    Color and Shape:Solid
    Molecular weight:407.53

    Ref: TM-T26969

  • PXS-6302 hydrochloride
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    PXS-6302 hydrochloride

    CAS:
    <p>PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3</p>
    Formula:C10H11ClF3NO2S
    Purity:99.89%
    Color and Shape:Soild
    Molecular weight:301.71

    Ref: TM-T60438L

  • Setileuton
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    Setileuton

    CAS:
    <p>Setileuton (MK0633) is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.</p>
    Formula:C22H17F4N3O4
    Purity:98.85% - 99.35%
    Color and Shape:Solid
    Molecular weight:463.38

    Ref: TM-T34624

  • h15-LOX-2 inhibitor 3
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    h15-LOX-2 inhibitor 3

    CAS:
    <p>Compound 13, identified as h15-LOX-2 inhibitor 3, exhibits inhibitory activity against h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively.</p>
    Formula:C22H13N5O3
    Color and Shape:Solid
    Molecular weight:395.37

    Ref: TM-T200110

  • AZD 4407
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    AZD 4407

    CAS:
    <p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>
    Formula:C19H21NO3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:375.5

    Ref: TM-T10438

  • CymitQuimica logo
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    ALOX15-IN-1

    <p>ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.</p>
    Formula:C24H31N3O5S
    Color and Shape:Solid
    Molecular weight:473.59

    Ref: TM-T63075