Microbiology/Virology
Microbiology and virology inhibitors are compounds that target microorganisms, including bacteria, viruses, and fungi, disrupting their growth, replication, or survival. These inhibitors are essential for studying microbial pathogenesis, understanding resistance mechanisms, and developing new antimicrobial and antiviral therapies. Inhibitors in this category are used to combat infectious diseases, explore microbial ecology, and investigate host-pathogen interactions. At CymitQuimica, we provide a broad selection of high-quality microbiology and virology inhibitors to support your research in infectious diseases, microbiology, and virology.
Subcategories of "Microbiology/Virology"
- Antibacterial(3,365 products)
- Antibiotic(937 products)
- Antifection(27 products)
- DHFR(30 products)
- DNA/RNA Synthesis(799 products)
- HBV(182 products)
- HIV Protease(496 products)
- HSV(99 products)
- Integrase(2 products)
- Ribosome(10 products)
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Found 6326 products of "Microbiology/Virology"
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Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.Formula:C23H27N3O2SColor and Shape:SolidMolecular weight:409.54BPR3P0128
CAS:BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].Formula:C22H18BrN3O2Color and Shape:SolidMolecular weight:436.30Neuraminidase-IN-18
CAS:Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].Formula:C22H18FN3O3SColor and Shape:SolidMolecular weight:423.46Antibacterial synergist 1
Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.Formula:C19H24N2O4Color and Shape:SolidMolecular weight:344.4Antibacterial agent 174
CAS:Compound 174 (Compound 5g), an antibacterial agent, exhibits potent anti-infective properties in vivo along with appreciable pharmacokinetic profiles. This highly active substance demonstrates favorable biofilm removal capabilities, low hemolysis, and acceptable mammalian cell toxicity [1].Formula:C25H30FN2NaO5Color and Shape:SolidMolecular weight:480.5Polθ-IN-6
CAS:Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.Formula:C25H23N3O3SColor and Shape:SolidMolecular weight:445.53WRN inhibitor 12
CAS:WRN inhibitor 12 (compound 5) serves as an inhibitor for the WRN helicase.Formula:C33H33ClF3N9O5Color and Shape:SolidMolecular weight:728.12Antibacterial agent 172
CAS:Antibacterial Agent 172 (Compound 6a), a Clostridioides difficile (Cd) SpoVD inhibitor with an IC50 value of 89 nM, effectively inhibits the sporulation of Clostridioides difficile. It is useful for research on bacterial infections [1].Formula:C21H21N9O5S2Color and Shape:SolidMolecular weight:543.58Doxazosin impurity 12
CAS:Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.
Formula:C10H6O5SColor and Shape:SolidMolecular weight:238.217Anti-ToCV agent 1
Anti-ToCV agent 1 can be used as a potential anti-ToCV drug.Formula:C22H19FN2O5SColor and Shape:SolidMolecular weight:442.46Urease-IN-16
CAS:Urease-IN-16, with an IC50 of 132 µmol/L, is a urease inhibitor that coordinates with nickel atoms through the oxygen atoms of either carbonyl or boronic acid groups. This compound holds significant potential as an additive in the development of efficient fertilizers and medical applications.Formula:C14H17BN2O4SColor and Shape:SolidMolecular weight:320.17Antiviral agent 7
Antiviral agent 7 is a peptide-based coating that kills viruses.Formula:C29H31F2N3O6Color and Shape:SolidMolecular weight:555.57Antibacterial agent 281
CAS:Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Formula:C23H24N6OColor and Shape:SolidMolecular weight:400.48Pyrromycin
CAS:Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.Formula:C30H35NO11Color and Shape:SolidMolecular weight:585.60Mer-NF5003F
CAS:Mer-NF5003F (Stachybotrydial; F 1839M) is a sesquiterpene isolated from Stachybotrys, effective in inhibiting avian myeloblastosis virus (AMV) protease with an IC50 of 7.8 μM. It also inhibits sialyltransferases ST6N, ST3O, and ST3N with IC50 values of 0.61, 6.7, and 10 μg/mL, respectively, and fucosyltransferase with an IC50 of 11.3 μg/mL. Additionally, Mer-NF5003F exhibits in vitro activity against herpes simplex virus HSV-1 (IC50=4.32 μg/mL) and multi-drug-resistant Plasmodium falciparum K1 strain (IC50=0.85 μg/mL).Formula:C23H30O5Molecular weight:386.48(-)-15-Deoxyspergualin
CAS:(-)-15-Deoxyspergualin is a potent antitumor agent that demonstrates significant inhibition against mouse leukemia L-1210.Formula:C17H37N7O3Color and Shape:SolidMolecular weight:387.52MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Formula:C9H12BN7O5S2Color and Shape:SolidMolecular weight:373.18Streptothricin F
CAS:Streptothricin F is a biochemical.Formula:C19H34N8O8Color and Shape:SolidMolecular weight:502.52MK-8876
CAS:MK-8876 is an Inhibitor of HCV NS5B Site D.Formula:C32H24F2N4O5SPurity:98%Color and Shape:SolidMolecular weight:614.62Pyriftalid
CAS:Pyriftalid is a novel insecticide known for its potent inhibitory activity against a variety of pests. It is widely utilized in agriculture to effectively manage crop pests, thereby enhancing both the yield and quality of crops. Additionally, research is exploring the use of Pyriftalid in boosting plant resistance to pests and diseases.Formula:C15H14N2O4SColor and Shape:SolidMolecular weight:318.35QPX7728 methoxy acetoxy methy ester
CAS:QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.Formula:C14H14BFO7Purity:98%Color and Shape:SolidMolecular weight:324.07Lentiginosine
CAS:Lentiginosine is a selective amyloglucosidase inhibitor.Formula:C8H15NO2Color and Shape:SolidMolecular weight:157.21Benzisothiazolone
CAS:Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.Formula:C7H5NOSColor and Shape:SolidMolecular weight:151.19EFdA-TP tetrasodium
CAS:EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.Formula:C12H11FN5Na4O12P3Purity:98%Color and Shape:SolidMolecular weight:621.12Antibacterial agent 82
Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].Formula:C22H18N2O2Color and Shape:SolidMolecular weight:342.39G247
G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.Formula:C24H19Cl2FO3Color and Shape:SolidMolecular weight:445.31Glasmacinal
CAS:Glasmacinal is a non-antibacterial macrolide compound with anti-inflammatory activities.Formula:C37H62N2O10Color and Shape:SolidMolecular weight:694.90A 76889
CAS:A 76889 is an inhibitor of HIV-1 protease.Formula:C44H58N8O6Purity:98%Color and Shape:SolidMolecular weight:794.98And1 degrader 1
CAS:And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.Formula:C26H27Cl2N3OColor and Shape:SolidMolecular weight:468.42GSK 932121
CAS:GSK 932121: potent antimalarial, targets P. falciparum by inhibiting cytochrome bc1 in the electron transport chain.Formula:C20H15ClF3NO4Purity:98%Color and Shape:SolidMolecular weight:425.79GR 122222X
CAS:GR 122222X is an inhibitor of topoisomerase II.Formula:C26H35N5O11SPurity:98%Color and Shape:SolidMolecular weight:625.65Lapyrium chloride
CAS:Lapyrium chloride (Emcol E 607) is a broad-spectrum antibacterial agent that serves as a preservative and disinfectant.Formula:C21H35ClN2O3Molecular weight:398.97GC-78-HCl
CAS:GC-78-HCl is an orally active, non-peptidic SARS-CoV-2 Mpro inhibitor with an enzyme IC50 of 0.19 μM. It exhibits strong anti-coronavirus activity and favorable pharmacokinetic properties.Formula:C25H25Cl3N4O4Molecular weight:551.85LasR antagonist 1
CAS:LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].Formula:C20H15F3N2O3Color and Shape:SolidMolecular weight:388.34TBAJ-5307
CAS:TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].Formula:C30H35BrN4O6Color and Shape:SolidMolecular weight:627.53Uridine 3',5'-diphosphate
CAS:Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].Formula:C9H14N2O12P2Color and Shape:SolidMolecular weight:404.16VV261
CAS:VV261 is an orally active inhibitor of the Influenza Virus. It exhibits activity against the Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) and the Lymphocytic Choriomeningitis Virus (LCMV), with EC50 values of 0.89 and 0.15, respectively.Formula:C28H34FN3O11Color and Shape:SolidMolecular weight:607.58SHEN26
CAS:SHEN26 (ATY014) is a potent, orally active RdRp inhibitor with an IC50 of 1.36 μM for SARS-CoV-2. As a 5'-cyclohexanecarboxylate derivative of GS-441524, SHEN26 inhibits viral nucleic acid synthesis, achieving antiviral effects. SHEN26 can be used for COVID-19 research [1] [2].Formula:C19H23N5O5Color and Shape:SolidMolecular weight:401.42PAV-104
CAS:PAV-104 inhibits the replication of SARS-CoV-2 at a MOI of 0.01. It interacts with the SARS-CoV-2 nucleocapsid (N) and disrupts its oligomerization, thereby preventing particle assembly.Formula:C29H35N5O6SColor and Shape:SolidMolecular weight:581.68Antibacterial agent 169
CAS:Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].
Formula:C19H25Cl2N5O3Color and Shape:SolidMolecular weight:442.34Metallo-β-lactamase-IN-13
CAS:Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].Formula:C15H10F3N7O2S2Color and Shape:SolidMolecular weight:441.41BioA-IN-1
CAS:BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.Formula:C18H17NO3SColor and Shape:SolidMolecular weight:327.397Altersolanol A
CAS:Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.Formula:C16H16O8Color and Shape:SolidMolecular weight:336.29TAN-1057C
CAS:TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).Formula:C13H25N9O3Color and Shape:SolidMolecular weight:355.4Antibacterial agent 188
CAS:Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].Formula:C12H10N4SColor and Shape:SolidMolecular weight:242.3CMX990
CAS:CMX990, a SARS-CoV-2 3CL protease inhibitor, exhibits EC90 values of 9.6 nM in human bronchial epithelial cells (HBECs) and 101 nM in HeLa-ACE2 cells. It also demonstrates good ADME and pharmacokinetic properties [1].Formula:C22H32F3N3O6Color and Shape:SolidMolecular weight:491.50LpxA-IN-1
CAS:LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosaFormula:C21H11D7F3N5O3Color and Shape:SolidMolecular weight:452.44iPAF1C
CAS:iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].
Formula:C27H26BrFN4OColor and Shape:SolidMolecular weight:521.42PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Formula:C18H20ClN3OSColor and Shape:SolidMolecular weight:361.89Elongation factor P-IN-2
Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.Formula:C16H35N3O2Color and Shape:SolidMolecular weight:301.47
