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5-HT Receptor

5-HT Receptor

5-HT receptors, also known as serotonin receptors, are a group of G protein-coupled receptors (GPCRs) that mediate the effects of serotonin, a neurotransmitter involved in mood regulation, anxiety, sleep, appetite, and other physiological processes. These receptors are divided into several subtypes, each with distinct functions and pharmacological properties. 5-HT receptor modulators are widely studied for their roles in treating depression, anxiety disorders, and other neuropsychiatric conditions. At CymitQuimica, we offer a range of high-quality 5-HT receptor modulators to support your research in neuropharmacology, mood disorders, and GPCR signaling.

Found 1025 products of "5-HT Receptor"

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  • 8 Hydroxy PIPAT oxalate
    Targetmol
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    8 Hydroxy PIPAT oxalate

    CAS:
    8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.
    Formula:C18H24INO5
    Color and Shape:Solid
    Molecular weight:461.29

    Ref: TM-T201052

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  • LK-732
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    LK-732

    CAS:
    LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.
    Formula:C25H29N5O3S
    Color and Shape:Solid
    Molecular weight:479.59

    Ref: TM-T201818

    10mg
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  • AAZ-A 154 mesylate
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    AAZ-A 154 mesylate

    CAS:
    AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.
    Formula:C15H24N2O4S
    Color and Shape:Solid
    Molecular weight:328.43

    Ref: TM-T200486

    25mg
    1,539.00€
    50mg
    1,941.00€
    100mg
    2,451.00€
  • LY 215840
    Targetmol
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    LY 215840

    CAS:
    5-HT2/5-HT7 receptor antagonist
    Formula:C24H33N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:395.54

    Ref: TM-T22940

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  • Flucopride
    Targetmol
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    Flucopride

    CAS:
    Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.
    Formula:C22H33FN2O2
    Color and Shape:Solid
    Molecular weight:376.51

    Ref: TM-T201815

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  • R-137696
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    R-137696

    CAS:
    R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.
    Formula:C17H23N3O2
    Color and Shape:Solid
    Molecular weight:301.38

    Ref: TM-T201501

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  • AGH-107
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    AGH-107

    CAS:
    AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.
    Formula:C13H12IN3
    Color and Shape:Solid
    Molecular weight:337.16

    Ref: TM-T201735

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  • Rodatristat ethyl
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    Rodatristat ethyl

    CAS:
    Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.
    Formula:C29H31ClF3N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:590.04

    Ref: TM-T16779

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  • Elzasonan hydrochloride
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    Elzasonan hydrochloride

    CAS:
    Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.
    Formula:C22H24Cl3N3OS
    Color and Shape:Solid
    Molecular weight:484.87

    Ref: TM-T201763

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  • Tipindole
    Targetmol
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    Tipindole

    CAS:
    Tipindole is a serotonin antagonist utilized in research related to depression.
    Formula:C16H20N2O2S
    Color and Shape:Solid
    Molecular weight:304.41

    Ref: TM-T201819

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  • Etoperidone
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    Etoperidone

    CAS:
    Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).
    Formula:C19H28ClN5O
    Color and Shape:Solid
    Molecular weight:377.91

    Ref: TM-T201838

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  • ASP-2205
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    ASP-2205

    CAS:
    ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.
    Formula:C19H28N2O
    Color and Shape:Solid
    Molecular weight:300.44

    Ref: TM-T201450

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  • YM-31636 free base
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    YM-31636 free base

    CAS:
    YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.
    Formula:C14H11N3S
    Color and Shape:Solid
    Molecular weight:253.32

    Ref: TM-T201587

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  • AAZ-A 154 benzoate
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    AAZ-A 154 benzoate

    CAS:
    AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.
    Formula:C21H26N2O3
    Color and Shape:Solid
    Molecular weight:354.44

    Ref: TM-T200491

    25mg
    1,458.00€
    50mg
    1,839.00€
    100mg
    2,322.00€
  • SB-224289 hydrochloride
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    SB-224289 hydrochloride

    CAS:
    SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.
    Formula:C32H33ClN4O3
    Purity:98.99% - 99.96%
    Color and Shape:Solid
    Molecular weight:557.08

    Ref: TM-T12841

    1mg
    42.00€
    5mg
    88.00€
    10mg
    115.00€
    25mg
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    50mg
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    1mL*10mM (DMSO)
    101.00€
  • Arotinolol
    Targetmol
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    Arotinolol

    CAS:
    Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.
    Formula:C15H21N3O2S3
    Color and Shape:White Solid
    Molecular weight:371.54

    Ref: TM-T10371

    1mg
    Discontinued
    Discontinued product
  • SB-399885 hydrochloride
    Targetmol
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    SB-399885 hydrochloride

    CAS:
    SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.
    Formula:C18H22Cl3N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:482.81

    Ref: TM-T12843

    1mg
    Discontinued
    Discontinued product
  • 7-Desmethyl-agomelatine
    Targetmol
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    7-Desmethyl-agomelatine

    CAS:
    7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.
    Formula:C14H15NO2
    Color and Shape:Solid
    Molecular weight:229.27

    Ref: TM-T10193

    1mg
    Discontinued
    Discontinued product
  • Pumosetrag Hydrochloride
    Targetmol
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    Pumosetrag Hydrochloride

    CAS:
    Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.
    Formula:C15H18ClN3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:339.84

    Ref: TM-T16683

    1mg
    Discontinued
    Discontinued product
  • Desmethyl cariprazine
    Targetmol
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    Desmethyl cariprazine

    CAS:
    Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).
    Formula:C20H30Cl2N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:413.38

    Ref: TM-T15100

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    500mg
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    Discontinued product
  • Sarizotan
    Targetmol
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    Sarizotan

    CAS:
    Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.
    Formula:C22H21FN2O
    Color and Shape:Solid
    Molecular weight:348.421

    Ref: TM-T40439

    ne
    Discontinued
    Discontinued product
  • BRL 15572
    Targetmol
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    BRL 15572

    CAS:
    BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.
    Formula:C25H27ClN2O
    Color and Shape:Solid
    Molecular weight:406.95

    Ref: TM-T64501

    ne
    Discontinued
    Discontinued product
  • 2-Methyl-5-HT hydrochloride
    Targetmol
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    2-Methyl-5-HT hydrochloride

    CAS:
    2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
    Formula:C11H15ClN2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:226.7

    Ref: TM-T10075L2

    25mg
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    100mg
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    Discontinued product
  • RU 24969 succinate
    Targetmol
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    RU 24969 succinate

    CAS:

    RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.

    Formula:C18H22N2O5
    Color and Shape:Solid
    Molecular weight:346.38

    Ref: TM-T71502

    50mg
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    100mg
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    Discontinued product
  • Flumexadol
    Targetmol
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    Flumexadol

    CAS:
    Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.
    Formula:C11H12F3NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:231.21

    Ref: TM-T11302

    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product