Beta Amyloid
Beta Amyloid inhibitors are compounds that target and prevent the formation or aggregation of beta-amyloid peptides, which are implicated in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is a hallmark of the disease, leading to neuronal dysfunction and cognitive decline. Inhibitors of beta-amyloid aggregation are being explored as potential therapeutic agents to slow or prevent the progression of Alzheimer's disease. At CymitQuimica, we provide a range of beta-amyloid inhibitors to support your research in neurodegeneration, protein aggregation, and Alzheimer's therapy.
Found 241 products for "Beta Amyloid".
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Cromoglicic acid
CAS:Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.Formula:C23H16O11Purity:99.55% - >99.99%Color and Shape:White SolidMolecular weight:468.37Solanezumab
CAS:Solanezumab (LY 2062430) is a monoclonal antibody that binds preferentially to soluble amyloid and promotes its clearance from the brain.Purity:96.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 96.3% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:144.07 kDaγ-Secretase modulator 13
CAS:γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's disease and tumors.Formula:C22H23FN6SPurity:99.79%Color and Shape:SolidMolecular weight:422.524-Hydroxyindole
CAS:4-Hydroxyindole: aromatic, antioxidant, used in cancer treatment and preventing neurodegenerative diseases.Formula:C8H7NOPurity:97.05% - 98.13%Color and Shape:SolidMolecular weight:133.15Ponezumab
CAS:Ponezumab is a humanized mAb targeting Abeta40 that research into Alzheimer's and brain amyloid deposits via a peripheral clearance mechanism.Purity:95%Color and Shape:Transparent LiquidMolecular weight:145.66 kDaRemternetug
CAS:Remternetug (LY3372993) is a humanised monoclonal antibody targeting N3pG-Aβ, recognising pyroglutamated Aβ within amyloid plaques, Alzheimer's disease.Purity:95% - 97.6% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:144.87 kDaDCDAPH
CAS:DCDAPH, a NIRF probe (λ597/665 nm), detects β-amyloid plaques with high affinity (Ki=37 nM, Kd=27 nM), and crosses the blood-brain barrier.Formula:C16H15N3Color and Shape:SolidMolecular weight:249.31Bapineuzumab
CAS:Bapineuzumab (AAB-001) is a humanised monoclonal antibody targeting amyloid-beta (Aβ), soluble and oligomeric forms of amyloid β, Alzheimer's disease (AD).Purity:95%Color and Shape:Transparent LiquidMolecular weight:145.86 kDaDezamizumab
CAS:Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.Purity:95% - 98.2% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.82 kDaHomotaurine-D6
CAS:Homotaurine-D6 is a deuterated compound of Homotaurine. Homotaurine (T0883) has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine (T0883) has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.Formula:C3D6H3NO3SColor and Shape:SolidMolecular weight:145.214-(6-Bromo-2-benzothiazolyl)benzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.Formula:C13H9BrN2SPurity:98%Color and Shape:SolidMolecular weight:305.19Eprodisate
CAS:Eprodisate disrupts protein-glycosaminoglycan binding, halting amyloid fibril formation, potentially delaying AA amyloidosis progression.Formula:C3H8O6S2Color and Shape:SolidMolecular weight:204.224-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Formula:C14H11BrN2SPurity:98%Color and Shape:SolidMolecular weight:319.22Aftin-5
CAS:Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.Formula:C19H26N6OColor and Shape:SolidMolecular weight:354.45Nicardipine pyridine metabolite II
CAS:Nicardipine pyridine metabolite II is a biaoctive chemical.Formula:C26H27N3O6Color and Shape:SolidMolecular weight:477.51SV5
CAS:SV5: potent anti-Alzheimer's, protects SHSY-5Y from Aβ1-42 death, stable with optimal pharmacology in plasma, antioxidant, neuroprotective.Formula:C21H30N2O4S2Color and Shape:SolidMolecular weight:438.6Caprospinol
CAS:Caprospinol inhibits β-Amyloid (Aβ) protein neurotoxicity.Formula:C33H52O4Purity:98%Color and Shape:SolidMolecular weight:512.76AZ4800
CAS:AZD4800 is a gamma secretase modulators.Formula:C24H29N5O3Color and Shape:SolidMolecular weight:435.52RS-0466
CAS:RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.Formula:C17H17N5O2Purity:98%Color and Shape:SolidMolecular weight:323.35BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Formula:C28H20F4N6O3Color and Shape:SolidMolecular weight:564.49TML-6
CAS:TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.Formula:C30H37NO7Purity:99.71%Color and Shape:White SolidMolecular weight:523.62Ref: TM-T37148
1mg94.00€5mg222.00€1mL*10mM (DMSO)256.00€10mg356.00€25mg708.00€50mg1,063.00€100mg1,674.00€KMS88009
CAS:KMS88009 is an amyloid-β aggregation inhibitor that acts by ameliorating neurodegenerative disorder.Formula:C19H19NO2Color and Shape:SolidMolecular weight:293.36Antioxidant agent-2
CAS:Antioxidant agent-2 (3c), BBB-permeable, selectively chelates metals; shows neuroprotection, fights liver damage in Alzheimer's research.Formula:C23H26N2O7Color and Shape:SolidMolecular weight:442.46BACE1/2-IN-1
CAS:BACE1/2-IN-1 inhibits BACE1/2 with IC50s of 0.01μM/0.0053μM, has better permeability and lower Pgp efflux but reduced metabolic stability.Formula:C21H31N5OSColor and Shape:SolidMolecular weight:401.57SEN-1269
CAS:SEN-1269 prevents amyloid-β aggregation, shields neurons, and improves memory by hindering Aβ(1-42)-induced issues.Formula:C18H18N4O2Purity:98%Color and Shape:SolidMolecular weight:322.36AY1511
CAS:AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].Formula:C17H14O6Color and Shape:SolidMolecular weight:314.29q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Formula:C21H14O6S4Color and Shape:SolidMolecular weight:490.59Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFormula:C22H30N6OColor and Shape:SolidMolecular weight:394.51LC kinetic stabilizer-2
CAS:LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.Formula:C28H31N3O3Color and Shape:SolidMolecular weight:457.56γ-Secretase modulator 12
CAS:γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM.Formula:C25H23N3O2Color and Shape:SolidMolecular weight:397.47RU-505
CAS:RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.Formula:C28H32FN5OPurity:98%Color and Shape:SolidMolecular weight:473.58BTA-1
CAS:BTA-1 is an uncharged derivative of thioflavin-T that has high affinity for Aβ fibrils and shows very good brain entry and clearance [1].Formula:C14H12N2SColor and Shape:SolidMolecular weight:240.32CGP52411
CAS:CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM).Formula:C20H15N3O2Purity:99.78%Color and Shape:SolidMolecular weight:329.35Astrophloxine
CAS:Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue andFormula:C27H33IN2Purity:99.89%Color and Shape:SolidMolecular weight:512.47Aβ Fibrillization modulator 1
CAS:Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.Formula:C17H12N4O3SSeColor and Shape:SolidMolecular weight:431.33Neuroinflammatory-IN-2
CAS:Neuroinflammatory-IN-2: anti-neuroinflammatory, inhibits MAO-B (IC50: 10.30µM), 96.33% Aβ1-42 aggregation reduction, neuroprotective in PC-12 cells.Formula:C25H27FN2O3Color and Shape:SolidMolecular weight:422.49ELND006
CAS:ELND006, an oral Alzheimer's drug, has improved bioavailability as a nanosuspension, and food doesn't affect it.Formula:C20H14F5N3O2SColor and Shape:SolidMolecular weight:455.4TC-E 5006
CAS:γ-secretase modulatorFormula:C29H29F4NO2Purity:98%Color and Shape:SolidMolecular weight:499.54OAB-14
CAS:OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.Formula:C32H46N4O2Color and Shape:SolidMolecular weight:518.73YIAD-0205
CAS:YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familialFormula:C26H16Br2ClN3Color and Shape:SolidMolecular weight:565.69K 01-162
CAS:K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.Formula:C15H14BrNColor and Shape:SolidMolecular weight:288.18Chrysamine G
CAS:Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.Formula:C26H16N4Na2O6Color and Shape:SolidMolecular weight:526.416Glutaminyl Cyclase Inhibitor 2
CAS:Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor (IC50: 1.23 μM).Formula:C19H20FN3Purity:98%Color and Shape:SolidMolecular weight:309.38JNJ-40418677
CAS:JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.Formula:C26H22F6O2Purity:98%Color and Shape:SolidMolecular weight:480.44BChE-IN-8
CAS:BChE-IN-8, compound 20, is a potent oral BChE inhibitor effective on eqBChE and hBChE, crosses blood-brain barrier, and may help in Alzheimer's research.Formula:C18H12BrN7O2Color and Shape:SolidMolecular weight:438.24THK-523
CAS:THK-523 selectively binds to tau in Alzheimer's, potent in vitro/vivo. 18F-THK523 excels in tau imaging.Formula:C17H15FN2OColor and Shape:SolidMolecular weight:282.31BI-1408
CAS:BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).Formula:C22H23FN6Purity:99.63%Color and Shape:SolidMolecular weight:390.46Aβ-IN-1
CAS:Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).Formula:C35H49NPurity:99.1%Color and Shape:SolidMolecular weight:483.77Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Formula:C26H27NO6Purity:99.85%Color and Shape:White SolidMolecular weight:449.5Ref: TM-T31773
1mg73.00€2mg98.00€5mg165.00€10mg295.00€25mg532.00€50mg800.00€100mg954.00€200mg1,288.00€PPI-1019
CAS:PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).Formula:C36H54N6O5Purity:95.16% - 98.16%Color and Shape:SolidMolecular weight:650.85
