Beta Amyloid
Beta Amyloid inhibitors are compounds that target and prevent the formation or aggregation of beta-amyloid peptides, which are implicated in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is a hallmark of the disease, leading to neuronal dysfunction and cognitive decline. Inhibitors of beta-amyloid aggregation are being explored as potential therapeutic agents to slow or prevent the progression of Alzheimer's disease. At CymitQuimica, we provide a range of beta-amyloid inhibitors to support your research in neurodegeneration, protein aggregation, and Alzheimer's therapy.
Found 231 products of "Beta Amyloid"
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4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Formula:C14H11BrN2SPurity:98%Color and Shape:SolidMolecular weight:319.22Nicardipine pyridine metabolite II
CAS:Nicardipine pyridine metabolite II is a biaoctive chemical.Formula:C26H27N3O6Color and Shape:SolidMolecular weight:477.51Eprodisate
CAS:Eprodisate disrupts protein-glycosaminoglycan binding, halting amyloid fibril formation, potentially delaying AA amyloidosis progression.Formula:C3H8O6S2Color and Shape:SolidMolecular weight:204.22Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFormula:C22H30N6OColor and Shape:SolidMolecular weight:394.51BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Formula:C28H20F4N6O3Color and Shape:SolidMolecular weight:564.49Caprospinol
CAS:Caprospinol inhibits β-Amyloid (Aβ) protein neurotoxicity.Formula:C33H52O4Purity:98%Color and Shape:SolidMolecular weight:512.76ELND006
CAS:ELND006, an oral Alzheimer's drug, has improved bioavailability as a nanosuspension, and food doesn't affect it.Formula:C20H14F5N3O2SColor and Shape:SolidMolecular weight:455.4AZ4800
CAS:AZD4800 is a gamma secretase modulators.Formula:C24H29N5O3Color and Shape:SolidMolecular weight:435.52q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Formula:C21H14O6S4Color and Shape:SolidMolecular weight:490.59BTA-1
CAS:BTA-1 is an uncharged derivative of thioflavin-T that has high affinity for Aβ fibrils and shows very good brain entry and clearance [1].Formula:C14H12N2SColor and Shape:SolidMolecular weight:240.32Neuroinflammatory-IN-2
CAS:Neuroinflammatory-IN-2: anti-neuroinflammatory, inhibits MAO-B (IC50: 10.30µM), 96.33% Aβ1-42 aggregation reduction, neuroprotective in PC-12 cells.Formula:C25H27FN2O3Color and Shape:SolidMolecular weight:422.49γ-Secretase modulator 12
CAS:γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM.Formula:C25H23N3O2Color and Shape:SolidMolecular weight:397.47JNJ-40418677
CAS:JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.Formula:C26H22F6O2Purity:98%Color and Shape:SolidMolecular weight:480.44Aβ Fibrillization modulator 1
CAS:Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.Formula:C17H12N4O3SSeColor and Shape:SolidMolecular weight:431.33Glutaminyl Cyclase Inhibitor 2
CAS:Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor (IC50: 1.23 μM).Formula:C19H20FN3Purity:98%Color and Shape:SolidMolecular weight:309.38SV5
CAS:SV5: potent anti-Alzheimer's, protects SHSY-5Y from Aβ1-42 death, stable with optimal pharmacology in plasma, antioxidant, neuroprotective.Formula:C21H30N2O4S2Color and Shape:SolidMolecular weight:438.6KMS88009
CAS:KMS88009 is an amyloid-β aggregation inhibitor that acts by ameliorating neurodegenerative disorder.Formula:C19H19NO2Color and Shape:SolidMolecular weight:293.36BACE1/2-IN-1
CAS:BACE1/2-IN-1 inhibits BACE1/2 with IC50s of 0.01μM/0.0053μM, has better permeability and lower Pgp efflux but reduced metabolic stability.Formula:C21H31N5OSColor and Shape:SolidMolecular weight:401.57Chrysamine G
CAS:Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.Formula:C26H16N4Na2O6Color and Shape:SolidMolecular weight:526.416CGP52411
CAS:CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM).Formula:C20H15N3O2Purity:99.78%Color and Shape:SolidMolecular weight:329.35TML-6
CAS:TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.Formula:C30H37NO7Purity:99.71%Color and Shape:SolidMolecular weight:523.62Ref: TM-T37148
1mg94.00€5mg222.00€1mL*10mM (DMSO)256.00€10mg356.00€25mg708.00€50mg1,063.00€100mg1,674.00€K 01-162
CAS:K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.Formula:C15H14BrNColor and Shape:SolidMolecular weight:288.18BChE-IN-8
CAS:BChE-IN-8, compound 20, is a potent oral BChE inhibitor effective on eqBChE and hBChE, crosses blood-brain barrier, and may help in Alzheimer's research.Formula:C18H12BrN7O2Color and Shape:SolidMolecular weight:438.24RS-0466
CAS:RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.Formula:C17H17N5O2Purity:98%Color and Shape:SolidMolecular weight:323.35YIAD-0205
CAS:YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familialFormula:C26H16Br2ClN3Color and Shape:SolidMolecular weight:565.69Antioxidant agent-2
CAS:Antioxidant agent-2 (3c), BBB-permeable, selectively chelates metals; shows neuroprotection, fights liver damage in Alzheimer's research.Formula:C23H26N2O7Color and Shape:SolidMolecular weight:442.46SEN-1269
CAS:SEN-1269 prevents amyloid-β aggregation, shields neurons, and improves memory by hindering Aβ(1-42)-induced issues.Formula:C18H18N4O2Purity:98%Color and Shape:SolidMolecular weight:322.36LC kinetic stabilizer-2
CAS:LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.Formula:C28H31N3O3Color and Shape:SolidMolecular weight:457.56Astrophloxine
CAS:Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue andFormula:C27H33IN2Purity:99.89%Color and Shape:SolidMolecular weight:512.47OAB-14
CAS:OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.Formula:C32H46N4O2Color and Shape:SolidMolecular weight:518.73THK-523
CAS:THK-523 selectively binds to tau in Alzheimer's, potent in vitro/vivo. 18F-THK523 excels in tau imaging.Formula:C17H15FN2OColor and Shape:SolidMolecular weight:282.31AY1511
CAS:AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].Formula:C17H14O6Color and Shape:SolidMolecular weight:314.29TC-E 5006
CAS:γ-secretase modulatorFormula:C29H29F4NO2Purity:98%Color and Shape:SolidMolecular weight:499.54RU-505
CAS:RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.Formula:C28H32FN5OPurity:98%Color and Shape:SolidMolecular weight:473.58MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.Formula:C18H24N2O2Purity:99.93%Color and Shape:SolidMolecular weight:300.4Ref: TM-T60671
2mg39.00€5mg58.00€1mL*10mM (DMSO)66.00€10mg93.00€25mg167.00€50mg260.00€100mg378.00€200mg552.00€MK-3328
CAS:MK-3328, a potential Alzheimer's drug, binds β-Amyloid with strong affinity (IC50:10.5 nM) and may serve as a PET ligand to gauge plaque load.Formula:C14H9FN4OPurity:99.77% - >99.99%Color and Shape:SolidMolecular weight:268.25Ref: TM-T16094
1mg315.00€5mg745.00€10mg1,018.00€25mg1,431.00€50mg1,783.00€100mg2,250.00€500mg4,410.00€Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Formula:C26H27NO6Purity:98.99%Color and Shape:SolidMolecular weight:449.5Ref: TM-T31773
1mg73.00€2mg98.00€5mg165.00€10mg295.00€25mg532.00€50mg800.00€100mg954.00€200mg1,288.00€Aβ-IN-1
CAS:Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).Formula:C35H49NPurity:99.1%Color and Shape:SoildMolecular weight:483.77Ezeprogind disulfate
CAS:Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.Formula:C25H48N6O8S2Purity:99.72%Color and Shape:SolidMolecular weight:624.81Glutaminyl Cyclase Inhibitor 1
CAS:Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.Formula:C21H24FN3O2Purity:99.81%Color and Shape:SolidMolecular weight:369.43Aleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFormula:C28H27NO3Purity:99.21%Color and Shape:SolidMolecular weight:425.52Ref: TM-T29856
1mg54.00€5mg114.00€1mL*10mM (DMSO)126.00€10mg178.00€25mg409.00€50mg620.00€100mg982.00€200mg1,314.00€BI-1408
CAS:BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).Formula:C22H23FN6Purity:99.63%Color and Shape:SolidMolecular weight:390.46amyloid P-IN-1
CAS:amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, andFormula:C30H44N2O14Purity:99.76%Color and Shape:SolidMolecular weight:656.68PPI-1019
CAS:PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).Formula:C36H54N6O5Purity:95.16% - 98.16%Color and Shape:SolidMolecular weight:650.85rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Formula:C18H21FN4O2Purity:99.44%Color and Shape:SolidMolecular weight:344.38TRV-1387
CAS:TRV-1387, a benzofurazan derivative, inhibits the aggregation of tau and amyloid-β [1].Formula:C23H25F3N4O2Color and Shape:SolidMolecular weight:446.47PQM130
CAS:PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.Formula:C23H27NO4Purity:98.73%Color and Shape:SolidMolecular weight:381.46QM-FN-SO3
CAS:QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Formula:C29H25N4NaO3S2Color and Shape:SolidMolecular weight:564.65ELND007
CAS:ELND007 is a Gamma secretase inhibitor.Formula:C19H14F4N4O2SColor and Shape:SolidMolecular weight:438.4QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Formula:C19H13NO3Color and Shape:SolidMolecular weight:303.31
