Beta Amyloid
Beta Amyloid inhibitors are compounds that target and prevent the formation or aggregation of beta-amyloid peptides, which are implicated in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is a hallmark of the disease, leading to neuronal dysfunction and cognitive decline. Inhibitors of beta-amyloid aggregation are being explored as potential therapeutic agents to slow or prevent the progression of Alzheimer's disease. At CymitQuimica, we provide a range of beta-amyloid inhibitors to support your research in neurodegeneration, protein aggregation, and Alzheimer's therapy.
Found 231 products of "Beta Amyloid"
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PiB
CAS:PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.Formula:C14H12N2OSPurity:97.02%Color and Shape:SolidMolecular weight:256.32Ref: TM-T21000
2mg33.00€5mg48.00€1mL*10mM (DMSO)49.00€10mg62.00€25mg103.00€50mg155.00€100mg224.00€200mg331.00€Solanezumab
CAS:Solanezumab (LY 2062430) is a monoclonal antibody that binds preferentially to soluble amyloid and promotes its clearance from the brain.Purity:96.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 96.3% (SDS-PAGE); 97.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.07 kDaγ-Secretase modulator 13
CAS:γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's disease and tumors.Formula:C22H23FN6SPurity:99.79%Color and Shape:SolidMolecular weight:422.524-Hydroxyindole
CAS:4-Hydroxyindole: aromatic, antioxidant, used in cancer treatment and preventing neurodegenerative diseases.Formula:C8H7NOPurity:97.05% - 98.13%Color and Shape:Off-White Cyrstalline SolidMolecular weight:133.15Bapineuzumab
CAS:Bapineuzumab (AAB-001) is a humanised monoclonal antibody targeting amyloid-beta (Aβ), soluble and oligomeric forms of amyloid β, Alzheimer's disease (AD).Purity:95%Color and Shape:LiquidMolecular weight:145.86 kDaRemternetug
CAS:Remternetug (LY3372993) is a humanised monoclonal antibody targeting N3pG-Aβ, recognising pyroglutamated Aβ within amyloid plaques, Alzheimer's disease.Purity:95% - 97.6% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.87 kDaDezamizumab
CAS:Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.Purity:95% - 98.2% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.82 kDaHomotaurine-d6
CAS:Homotaurine-d6 is a deuterated compound of Homotaurine. Homotaurine has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.Formula:C3D6H3NO3SColor and Shape:SolidMolecular weight:145.214-(6-Bromo-2-benzothiazolyl)benzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.Formula:C13H9BrN2SPurity:98%Color and Shape:SolidMolecular weight:305.19Aftin-5
CAS:Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.Formula:C19H26N6OColor and Shape:SolidMolecular weight:354.454-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Formula:C14H11BrN2SPurity:98%Color and Shape:SolidMolecular weight:319.22Nicardipine pyridine metabolite II
CAS:Nicardipine pyridine metabolite II is a biaoctive chemical.Formula:C26H27N3O6Color and Shape:SolidMolecular weight:477.51Eprodisate
CAS:Eprodisate disrupts protein-glycosaminoglycan binding, halting amyloid fibril formation, potentially delaying AA amyloidosis progression.Formula:C3H8O6S2Color and Shape:SolidMolecular weight:204.22Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFormula:C22H30N6OColor and Shape:SolidMolecular weight:394.51BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Formula:C28H20F4N6O3Color and Shape:SolidMolecular weight:564.49Caprospinol
CAS:Caprospinol inhibits β-Amyloid (Aβ) protein neurotoxicity.Formula:C33H52O4Purity:98%Color and Shape:SolidMolecular weight:512.76ELND006
CAS:ELND006, an oral Alzheimer's drug, has improved bioavailability as a nanosuspension, and food doesn't affect it.Formula:C20H14F5N3O2SColor and Shape:SolidMolecular weight:455.4AZ4800
CAS:AZD4800 is a gamma secretase modulators.Formula:C24H29N5O3Color and Shape:SolidMolecular weight:435.52q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Formula:C21H14O6S4Color and Shape:SolidMolecular weight:490.59BTA-1
CAS:BTA-1 is an uncharged derivative of thioflavin-T that has high affinity for Aβ fibrils and shows very good brain entry and clearance [1].Formula:C14H12N2SColor and Shape:SolidMolecular weight:240.32
