Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 600 products of "Cyclooxygenase (COX) Inhibitors"
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Columbin
CAS:Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.Formula:C20H22O6Purity:99.34% - 99.74%Color and Shape:SolidMolecular weight:358.39S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formula:C14H14O4Purity:98.00% - ≥98%Color and Shape:SolidMolecular weight:246.267,3',4'-Tri-O-methylluteolin
CAS:7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).
Formula:C18H16O6Purity:98.66% - 99.79%Color and Shape:SolidMolecular weight:328.32Losartan Carboxaldehyde
CAS:Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.Formula:C22H21ClN6OPurity:99.1%Color and Shape:SolidMolecular weight:420.89Esculentoside A
CAS:Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.Formula:C42H66O16Purity:98% - 99.85%Color and Shape:SolidMolecular weight:826.96Diclofenac Epolamine
CAS:Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions.Formula:C20H24Cl2N2O3Purity:99.56%Color and Shape:SolidMolecular weight:411.32Psoralidin
CAS:Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.Formula:C20H16O5Purity:98% - 99.61%Color and Shape:SolidMolecular weight:336.34Ref: TM-T3399
2mg34.00€5mg50.00€1mL*10mM (DMSO)55.00€10mg81.00€25mg152.00€50mg230.00€100mg340.00€200mg497.00€2,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Formula:C14H22O2Purity:97.11%Color and Shape:PelletslargecrystalsMolecular weight:222.32(+)-Catechin Hydrate
CAS:(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biologicalFormula:C15H16O7Purity:99.03% - 99.96%Color and Shape:SolidMolecular weight:308.28CAFESTOL
CAS:Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.Formula:C20H28O3Purity:97.06% - 99.08%Color and Shape:SolidMolecular weight:316.43Otenaproxesul
CAS:Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.Formula:C21H19NO3SPurity:98.76% - 99.13%Color and Shape:SolidMolecular weight:365.45Ref: TM-T1867
2mg38.00€5mg57.00€1mL*10mM (DMSO)63.00€10mg93.00€25mg166.00€50mg260.00€100mg416.00€500mg888.00€Macelignan
CAS:Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus.Formula:C20H24O4Purity:98.01% - >99.99%Color and Shape:SolidMolecular weight:328.40Ref: TM-T3866
2mg37.00€5mg52.00€1mL*10mM (DMSO)63.00€10mg73.00€25mg105.00€50mg152.00€100mg215.00€200mg320.00€Chebulagic acid
CAS:Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.Formula:C41H30O27Purity:97.82% - 99.8%Color and Shape:SolidMolecular weight:954.66Ref: TM-TQ0180
1mg74.00€5mg157.00€10mg225.00€1mL*10mM (DMSO)244.00€25mg376.00€50mg560.00€100mg798.00€anemarsaponin B
CAS:Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activityFormula:C45H74O18Purity:99.06% - 99.11%Color and Shape:SolidMolecular weight:903.06Teriflunomide impurity 3
CAS:Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM).Formula:C14H11F3N2OPurity:99.62%Color and Shape:SolidMolecular weight:280.25Ref: TM-T9042
500mgTo inquire1mL*10mM (DMSO)34.00€10mg48.00€25mg86.00€50mg127.00€100mg200.00€200mg286.00€Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formula:C19H19FO4Purity:97.58% - 98%Color and Shape:SolidMolecular weight:330.35Sulindac sulfone
CAS:Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac. Sulindac sulfone is an inhibitor of aldose reductase (IC50 =367 nM).Formula:C20H17FO4SPurity:98.2% - 98.83%Color and Shape:SolidMolecular weight:372.41Ref: TM-T23403
5mg52.00€1mL*10mM (DMSO)52.00€10mg78.00€25mg119.00€50mg172.00€100mg259.00€200mg388.00€Hexahydrocurcumin
CAS:Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.Formula:C21H26O6Purity:99.43% - 99.88%Color and Shape:SolidMolecular weight:374.43Ref: TM-TQ0288
1mg84.00€5mg178.00€1mL*10mM (DMSO)294.00€10mg295.00€25mg595.00€50mg888.00€100mg1,251.00€Propyphenazone
CAS:Propyphenazone: an anti-inflammatory, analgesic, antipyretic pyrazolone; prodrug; COX-2 inhibitor.Formula:C14H18N2OPurity:99.64%Color and Shape:SolidMolecular weight:230.31Revaprazan hydrochloride
CAS:Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.Formula:C22H24ClFN4Purity:99.62% - 99.91%Color and Shape:SolidMolecular weight:398.9
