Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 602 products of "Cyclooxygenase (COX) Inhibitors"
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Tryptanthrin
CAS:Formula:C15H8N2O2Purity:>98.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:248.24Fenbufen
CAS:Formula:C16H14O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:254.29Dexketoprofen trometamol
CAS:Dexketoprofen trometamol is a modified non-selective COX inhibitor with a rapid onset of action that is available as both oral and parenteral formulations.Formula:C20H25NO6Purity:99.97% - 99.98%Color and Shape:SolidMolecular weight:375.42(S)-Flurbiprofen
CAS:Esflurbiprofen is an inhibitor of COX-1 and COX-2.Formula:C15H13FO2Purity:99.99%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:244.26Ginsenoside Rd
CAS:Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purity:99.13% - 99.92%Color and Shape:SolidMolecular weight:947.15Ref: TM-T2878
1mg37.00€5mg71.00€10mg99.00€1mL*10mM (DMSO)124.00€25mg170.00€50mg260.00€100mg394.00€200mg570.00€Indomethacin heptyl ester
CAS:Indomethacin heptyl ester is a non-selective inhibitor of both COX-1 and COX-2Formula:C26H30ClNO4Purity:99.86%Color and Shape:SolidMolecular weight:455.97Ref: TM-T22092
1mg50.00€2mg65.00€5mg120.00€10mg202.00€1mL*10mM (DMSO)202.00€25mg464.00€50mg677.00€100mg938.00€500mg1,882.00€Ibuprofen Piconol
CAS:Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Formula:C19H23NO2Purity:99.21%Color and Shape:SolidMolecular weight:297.39EIPA
CAS:EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.Formula:C11H18ClN7OPurity:96.62% - 99.981%Color and Shape:Off-White To Yellow SolidMolecular weight:299.76Ref: TM-TQ0157
2mg34.00€5mg47.00€1mL*10mM (DMSO)52.00€10mg71.00€25mg101.00€50mg163.00€100mg231.00€200mg341.00€Lobeglitazone
CAS:Lobeglitazone (CKD-501) is a dual PPARα/γ agonist thiazolidinedione antidiabetic that enhances insulin sensitivity.Formula:C24H24N4O5SColor and Shape:SolidMolecular weight:480.54AG126
CAS:AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). AG-126 weakly inhibits epidermal GFRK and platelet-derived GFRK.Formula:C10H5N3O3Purity:97.35%Color and Shape:SolidMolecular weight:215.16Harpagoside
CAS:Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.Formula:C24H30O11Purity:99.71% - ≥95%Color and Shape:White To Off-White PowderMolecular weight:494.49β-Elemonic Acid
CAS:β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.Formula:C30H46O3Purity:99.61% - 99.8%Color and Shape:SolidMolecular weight:454.68Ref: TM-T2S0618
1mg35.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg110.00€25mg192.00€50mg286.00€100mg425.00€200mg612.00€Tryptanthrin
CAS:Tryptanthrin is a natural DNA gyrase inhibitor.Formula:C15H8N2O2Purity:99.64% - 99.94%Color and Shape:SolidMolecular weight:248.24Dehydrodiisoeugenol
CAS:Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.Formula:C20H22O4Purity:99.97%Color and Shape:SolidMolecular weight:326.39α-Demethylnaproxen
CAS:α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)Formula:C13H12O3Purity:97.57%Color and Shape:Off-White SolidMolecular weight:216.23Ketorolac
CAS:Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.Formula:C15H13NO3Purity:99.68%Color and Shape:White Crystalline Or White PowderMolecular weight:255.27Loxoprofen sodium (dihydrate)
CAS:Loxoprofen sodium dihydrate: Non-steroidal anti-inflammatory with analgesic, antipyretic, antitumor effects; COX-1/COX-2 inhibitor. IC50: 6.5/13.5 μM.Formula:C15H21NaO5Color and Shape:SolidMolecular weight:304.318Veratric acid
CAS:Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-Formula:C9H10O4Purity:99.44%Color and Shape:SolidMolecular weight:182.17Ginsenoside Rg5
CAS:Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.Formula:C42H70O12Purity:98% - 99.65%Color and Shape:SolidMolecular weight:767.00Ref: TM-T6S1487
1mg107.00€5mg251.00€1mL*10mM (DMSO)341.00€10mg404.00€25mg665.00€50mg888.00€100mg1,251.00€Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purity:99.25%Color and Shape:Yellowish SolidMolecular weight:379.88Ref: TM-T6568
5mg44.00€1mL*10mM (DMSO)48.00€10mg66.00€25mg119.00€50mg177.00€100mg264.00€200mg394.00€500mg623.00€
