Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 598 products of "Cyclooxygenase (COX) Inhibitors"
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Ketorolac-d5
CAS:Ketorolac-d5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac is a non-steroidal anti-inflammatory agent and inhibitor of COX-1 and COX-2.Formula:C15H8D5NO3Purity:98.99%Color and Shape:SolidMolecular weight:260.34-AcetaMido-d3-antipyrine
CAS:4-AcetaMido-d3-antipyrine is a deuterated compound of 4-AcetaMido-antipyrine. 4-AcetaMido-antipyrine has a CAS number of 83-15-8.Formula:C13H12D3N3O2Color and Shape:SolidMolecular weight:248.30AHR-10037
CAS:AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.Formula:C15H13ClN2O2Purity:98%Color and Shape:SolidMolecular weight:288.73Amfenac
CAS:Amfenac promotes apoptosis in ARPE-19 cell culture.Formula:C15H13NO3Color and Shape:SolidMolecular weight:255.27Pelubiprofen
CAS:Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.Formula:C16H18O3Purity:99.69%Color and Shape:SolidMolecular weight:258.31Apricoxib
CAS:Apricoxib: oral NSAID with antiangiogenic, antineoplastic properties; inhibits COX-2, may reduce tumor growth and angiogenesis.Formula:C19H20N2O3SColor and Shape:SolidMolecular weight:356.44COX-2-IN-23
CAS:COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.Formula:C24H25N5O3S2Color and Shape:SolidMolecular weight:495.62COX-1/2-IN-3
CAS:COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].Formula:C14H8N2O8Color and Shape:SolidMolecular weight:332.22COX-1/2-IN-1
CAS:"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."Formula:C15H10BrClN2OColor and Shape:SolidMolecular weight:349.61L 748780
CAS:L 748780 is a selective inducible COX-2 inhibitor.Formula:C19H14Cl3NO4Purity:98%Color and Shape:SolidMolecular weight:426.68Naproxcinod
CAS:Naproxcinod is a derivative of naproxen, analgesic and anti-inflammatory, a COX-inhibitory nitric oxide donor (CINOD), osteoarthritis and inflammatory.Formula:C18H21NO6Purity:99.85%Color and Shape:SolidMolecular weight:347.36Naproxen ethyl ester
CAS:Naproxen ethyl ester, an NSAID similar to ibuprofen, reduces pain, fever, and inflammation. It's a non-selective COX inhibitor.Formula:C16H18O3Color and Shape:SolidMolecular weight:258.31Nitroflurbiprofen
CAS:Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensiveFormula:C19H20FNO5Purity:99.88%Color and Shape:SolidMolecular weight:361.36Ref: TM-T16329
1mg52.00€5mg94.00€10mg142.00€25mg236.00€50mg319.00€100mg450.00€200mg1,009.00€1mL*10mM (DMSO)100.00€COX-2-IN-28
CAS:COX-2-IN-28 is a potent and selective COX-2 inhibitor capable of acting on COX-2 (IC50: 0.054 μM), 15-LOX (IC50: 2.14 μM) and COX-1 (IC50: 13.21 μM).Formula:C30H27N7S3Color and Shape:SolidMolecular weight:581.78Glucametacine
CAS:Glucametacine is an anti-inflammatory agent.Formula:C25H27ClN2O8Color and Shape:SolidMolecular weight:518.94COX-2-IN-11
CAS:COX-2-IN-11 (compound 7b2) is a potent and selective COX-2 inhibitor. COX-2-IN-11 has the potential in inflammation disease research[1].Formula:C12H12OS3Color and Shape:SolidMolecular weight:268.42Naproxen etemesil
CAS:Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.Formula:C17H20O5SPurity:98%Color and Shape:SolidMolecular weight:336.4COX-2-IN-19
CAS:COX-2-IN-19, a potent COX-2 inhibitor, IC50 of 1.76 μM, has strong anti-inflammatory effects in vivo.Formula:C18H18N4O2SColor and Shape:SolidMolecular weight:354.43COX-2-IN-24
CAS:COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.Formula:C24H24BrN5O3S2Color and Shape:SolidMolecular weight:574.51Anti-inflammatory agent 56
CAS:Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits anti-oxidant and anti-inflammatory properties byFormula:C21H15F3N4O4SPurity:98%Color and Shape:SolidMolecular weight:476.43
