Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Found 598 products of "Cyclooxygenase (COX) Inhibitors"
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COX/5-LO-IN-1
CAS:COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.Formula:C16H15FN2O2SPurity:98%Color and Shape:SolidMolecular weight:318.37COX-2-IN-17
CAS:COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.Formula:C20H23ClN6O2Color and Shape:SolidMolecular weight:414.89COX-2-IN-18
CAS:COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.Formula:C18H19N3O3S2Color and Shape:SolidMolecular weight:389.49COX-2-IN-23
CAS:COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.Formula:C24H25N5O3S2Color and Shape:SolidMolecular weight:495.62Anti-inflammatory agent 8
CAS:Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.Formula:C18H15N5OS2Color and Shape:SolidMolecular weight:381.47Apricoxib
CAS:Apricoxib: oral NSAID with antiangiogenic, antineoplastic properties; inhibits COX-2, may reduce tumor growth and angiogenesis.Formula:C19H20N2O3SColor and Shape:SolidMolecular weight:356.44PD 127443
CAS:PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.Formula:C20H28N2OColor and Shape:SolidMolecular weight:312.45COX-2-IN-2
CAS:COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.Formula:C17H12FN3O2SPurity:97.62%Color and Shape:SolidMolecular weight:341.36Ref: TM-T10032
1mg163.00€5mg394.00€10mg632.00€25mg1,260.00€50mg2,008.00€100mg2,665.00€1mL*10mM (DMSO)401.00€COX-2-IN-26
CAS:COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.Formula:C23H21N7OS3Color and Shape:SolidMolecular weight:507.65Naproxen glucuronide
CAS:Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.Formula:C20H22O9Color and Shape:SolidMolecular weight:406.38SC57666
CAS:SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1.Formula:C18H17FO2SPurity:98.83%Color and Shape:SolidMolecular weight:316.39Ref: TM-T12860
1mg110.00€5mg231.00€10mg370.00€25mg632.00€50mg827.00€100mg1,071.00€200mg1,431.00€1mL*10mM (DMSO)255.00€COX-2-IN-32
CAS:COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.Formula:C25H24O6Purity:98%Color and Shape:SolidMolecular weight:420.45COX-2-IN-14
CAS:COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.Formula:C18H18N4O6Color and Shape:SolidMolecular weight:386.364Loxoprofenol-SRS tromethamine
CAS:Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.Formula:C19H31NO6Color and Shape:SolidMolecular weight:369.45Thiazolinobutazone
CAS:Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.Formula:C22H26N4O2SColor and Shape:SolidMolecular weight:410.53MK-0703
CAS:MK-0703 is a selective cyclooxygenase-2 inhibitor.Formula:C17H22O5SPurity:98%Color and Shape:SolidMolecular weight:338.42Etoricoxib HCl
CAS:Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.Formula:C18H16Cl2N2O2SColor and Shape:SolidMolecular weight:395.30PC407-ws
CAS:PC407-ws is a water-soluble novel COX-2 inhibitor.Formula:C24H18F3N3Na2O5SPurity:98%Color and Shape:SolidMolecular weight:563.46Isonixin
CAS:Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.Formula:C14H14N2O2Purity:98%Color and Shape:SolidMolecular weight:242.27Tenosal
CAS:Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.Formula:C12H8O4SPurity:98%Color and Shape:SolidMolecular weight:248.25
