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Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) Inhibitors

Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.

Found 612 products for "Cyclooxygenase (COX) Inhibitors".

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  • COX-2/NLRP3-IN-1

    CAS:
    COX-2/NLRP3-IN-1 (Compound 6k) is an inhibitor that targets COX-2 and NLRP3, exhibiting an IC50 value of 1.53 μM for COX-2. This compound exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway.
    Formula:C24H19Cl2N5OS
    Color and Shape:Solid
    Molecular weight:496.41

    Ref: TM-T209071

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • COX-2-IN-32

    CAS:
    COX-2-IN-32 is a selective COX-2 inhibitor; suppresses PGE2 synthesis; anti-inflammatory and analgesic research.
    Formula:C25H24O6
    Purity:98.11%
    Color and Shape:Yellow Solid
    Molecular weight:420.45

    Ref: TM-T79130

    1mg
    264.00€
    5mg
    650.00€
    10mg
    888.00€
    25mg
    1,369.00€
    50mg
    1,783.00€
  • L 748780

    CAS:
    L 748780 is a selective inducible COX-2 inhibitor.
    Formula:C19H14Cl3NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.68

    Ref: TM-T24360

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • LY 150310

    CAS:
    LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.
    Formula:C13H14N2
    Color and Shape:Solid
    Molecular weight:198.26

    Ref: TM-T27875

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • ZXX2-77

    CAS:
    ZXX2-77 is a cyclooxygenase-1 inhibitor.
    Formula:C13H13ClN2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.77

    Ref: TM-T24464

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • LY 25648

    CAS:
    LY 25648 is an antagonist of leukotriene B4.
    Formula:C19H27NO2S
    Color and Shape:Solid
    Molecular weight:333.49

    Ref: TM-T27906

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Lobeglitazone Sulfate

    CAS:
    Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.
    Formula:C24H26N4O9S2
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:578.61

    Ref: TM-T27841

    1mg
    71.00€
    5mg
    156.00€
    10mg
    241.00€
    25mg
    384.00€
    50mg
    572.00€
    100mg
    837.00€
    200mg
    1,125.00€
  • AHR-6293

    CAS:
    AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.
    Formula:C15H12ClNO3
    Color and Shape:Solid
    Molecular weight:289.71

    Ref: TM-T23684

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Flosulide

    CAS:
    Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.
    Formula:C16H13F2NO4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:353.34

    Ref: TM-T11296

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€
  • NCX 466

    CAS:
    cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor
    Formula:C20H24N2O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:436.41

    Ref: TM-T23062

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Etoricoxib HCl

    CAS:
    Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.
    Formula:C18H16Cl2N2O2S
    Color and Shape:Solid
    Molecular weight:395.30

    Ref: TM-T1574L

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • PC407-ws

    CAS:
    PC407-ws is a water-soluble novel COX-2 inhibitor.
    Formula:C24H18F3N3Na2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:563.46

    Ref: TM-T24600

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Isonixin

    CAS:
    Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.
    Formula:C14H14N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:242.27

    Ref: TM-T27633

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Prostaglandin G/H synthase 1 inhibitor

    CAS:
    Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.
    Formula:C13H11ClN2O
    Purity:99.76%
    Color and Shape:White Solid
    Molecular weight:246.692

    Ref: TM-T27066

    1mL*10mM (DMSO)
    33.00€
    500mg
    44.00€
    1g
    60.00€
  • Tenosal

    CAS:
    Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.
    Formula:C12H8O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:248.25

    Ref: TM-T13122

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • FR-188582

    CAS:
    FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).
    Formula:C16H13ClN2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:332.8

    Ref: TM-T15345

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€
  • RWJ 63556

    CAS:
    RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.
    Formula:C11H10FNO3S2
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:287.33

    Ref: TM-T12784

    1mg
    49.00€
    5mg
    87.00€
    1mL*10mM (DMSO)
    93.00€
    10mg
    138.00€
    25mg
    264.00€
    50mg
    403.00€
    100mg
    532.00€
    200mg
    705.00€
  • Eicosatetraynoic acid

    CAS:
    ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).
    Formula:C20H24O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.4

    Ref: TM-T11169

    5mg
    172.00€
    10mg
    314.00€
    25mg
    740.00€
    50mg
    1,288.00€
  • ATB-346, (S)-

    CAS:
    ATB-346(S) is a hydrogen sulfide-releasing anti-inflammatory that triggers melanoma cell death and inhibits tumor growth.
    Formula:C21H19NO3S
    Color and Shape:Solid
    Molecular weight:365.45

    Ref: TM-T71656

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • MK-0703

    CAS:
    MK-0703 is a selective cyclooxygenase-2 inhibitor.
    Formula:C17H22O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.42

    Ref: TM-T28052

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€