CaMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are compounds that block the activity of CaMK, a kinase involved in regulating various cellular processes, including synaptic plasticity, memory formation, and gene expression in the nervous system. CaMK plays a critical role in translating calcium signals into cellular responses, and its dysregulation is associated with neurological disorders. Inhibitors of CaMK are valuable tools for studying synaptic signaling, learning, and memory. At CymitQuimica, we offer CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Found 73 products of "CaMK"
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CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Formula:C70H105F3N14O15SColor and Shape:SolidMolecular weight:1471.72Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Formula:C105H189N31O26SPurity:96.7%Color and Shape:SolidMolecular weight:2333.88Calmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Formula:C231H373N69O70S2Purity:98%Color and Shape:SolidMolecular weight:5301.1MLCK Peptide
CAS:MLCK Peptide, a high-affinity (pM), fully reversible CaM-binding peptide, is derived from smooth muscle myosin light-chain kinase [1].Formula:C91H156N36O20Color and Shape:SolidMolecular weight:2074.44Purine riboside triphosphate
CAS:Purine riboside triphosphate resembles adenosine; inhibits cancer cell growth by blocking RNA/DNA synthesis.Formula:C10H15N4O13P3Color and Shape:SolidMolecular weight:492.17Purine riboside-5'-O-triphosphate sodium
CAS:Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 µM.Formula:C10H11N4Na4O13P3Color and Shape:SolidMolecular weight:580.09RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Color and Shape:Odour SolidCAMKIV Protein, Human, Recombinant (GST)
CAMKIV Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.Color and Shape:Lyophilized PowderMolecular weight:79 kDa (predicted); 100 kDa (reducing conditions)KN-62
CAS:KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.Formula:C38H35N5O6S2Purity:99.80% - >99.99%Color and Shape:White SolidMolecular weight:721.84Ref: TM-T2694
1mg34.00€2mg49.00€5mg71.00€10mg105.00€25mg207.00€50mg404.00€100mg592.00€1mL*10mM (DMSO)105.00€CALP2 acetate(261969-04-4 free base)
CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM.Formula:C68H104N14O13SPurity:97.43%Color and Shape:SolidMolecular weight:1357.7Syntide 2 acetate(108334-68-5 free base)
Syntide-2 acetate is a synthetic peptide recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII; Km = 12 μM).Formula:C70H126N20O20Purity:99.74%Color and Shape:SolidMolecular weight:1567.85Autocamtide-2-related inhibitory peptide
CAS:Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Formula:C64H116N22O19Purity:>99.99%Color and Shape:SolidMolecular weight:1497.74Autocamtide 2 TFA(129198-88-5 free base)
Autocamtide 2 TFA, selective CaMKII peptide substrate, used in its activity assay.Formula:C67H119F3N22O22Purity:98%Color and Shape:SolidMolecular weight:1641.79CaMKP Inhibitor
CAS:CaMKP Inhibitor can inhibit CaMKP.Formula:C10H8NNaO7S2Purity:96.55% - 99.98%Color and Shape:SolidMolecular weight:341.28Ref: TM-T2159
1mg39.00€5mg82.00€10mg120.00€25mg227.00€50mg334.00€100mg460.00€500mg1,035.00€1mL*10mM (DMSO)102.00€GSK3i XIII
CAS:GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.Formula:C18H19N5Purity:98.87%Color and Shape:SolidMolecular weight:305.38Ref: TM-T24111
1mg63.00€5mg114.00€10mg172.00€25mg279.00€50mg406.00€100mg572.00€1mL*10mM (DMSO)128.00€IGS-1.76
CAS:IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.Formula:C22H18N2OSPurity:98.18% - 98.56%Color and Shape:SolidMolecular weight:358.46KN-92
CAS:KN-92 is an inactive analog of the CaM kinase II inhibitor KN 93.Formula:C24H25ClN2O3SColor and Shape:SolidMolecular weight:456.98KN-93
CAS:KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Formula:C26H29ClN2O4SPurity:99.56% - 99.86%Color and Shape:White SolidMolecular weight:501.04Ref: TM-T2697
1mg54.00€2mg74.00€5mg107.00€10mg146.00€25mg289.00€50mg358.00€100mg523.00€1mL*10mM (DMSO)120.00€Trifluoperazine
CAS:Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Formula:C21H24F3N3SPurity:98.3% - 99.46%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:407.5NH125
CAS:NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Formula:C27H45IN2Purity:98.60%Color and Shape:SolidMolecular weight:524.56Ref: TM-T6605
1mg40.00€2mg52.00€5mg88.00€10mg119.00€25mg264.00€50mg454.00€100mg655.00€1mL*10mM (DMSO)87.00€
