CaMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are compounds that block the activity of CaMK, a kinase involved in regulating various cellular processes, including synaptic plasticity, memory formation, and gene expression in the nervous system. CaMK plays a critical role in translating calcium signals into cellular responses, and its dysregulation is associated with neurological disorders. Inhibitors of CaMK are valuable tools for studying synaptic signaling, learning, and memory. At CymitQuimica, we offer CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Found 73 products of "CaMK"
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CALP1 acetate
CALP1 acetate is a calmodulin (CaM) agonist (Kd of 88 µM) that binds to the CaM EF-hand/Ca2+-binding site.
Formula:C42H79N9O12Purity:99.63%Color and Shape:SolidMolecular weight:902.13CaMKII-IN-1
CAS:CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).Formula:C29H30ClN5O2SPurity:99.69%Color and Shape:SolidMolecular weight:548.1Ref: TM-T14860
1mg50.00€2mg71.00€5mg113.00€10mg166.00€25mg334.00€50mg520.00€100mg750.00€1mL*10mM (DMSO)137.00€lavendustin C
CAS:lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formula:C14H13NO5Purity:98.06%Color and Shape:Yellow To Tan PowderMolecular weight:275.26Ref: TM-T4185
1mg42.00€2mg55.00€5mg93.00€10mg152.00€25mg330.00€50mg492.00€100mg707.00€1mL*10mM (DMSO)90.00€STO-609
CAS:STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.
Formula:C19H10N2O3Purity:97.14% - 98.8%Color and Shape:SolidMolecular weight:314.29KN-92 hydrochloride
CAS:KN-92 hydrochloride is an inactive derivative of KN-93.Formula:C24H26Cl2N2O3SPurity:99.68%Color and Shape:SolidMolecular weight:493.45A-484954
CAS:A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor.Formula:C13H15N5O3Purity:97.47% - 99.86%Color and Shape:SolidMolecular weight:289.29Ref: TM-TQ0137
1mg43.00€2mg56.00€5mg88.00€10mg144.00€25mg305.00€50mg543.00€100mg775.00€1mL*10mM (DMSO)103.00€CaM kinase II inhibitor TFA salt
CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide (TFA)) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
Formula:C66H117F3N22O21Purity:>99.99%Color and Shape:SolidMolecular weight:1611.77L-6355
CAS:L-6355 is an agent of bioactive chemicals.Formula:C25H30INO3Color and Shape:SolidMolecular weight:519.42Zaldaride maleate
CAS:Zaldaride maleate blocks Ca2+, Na+, K+ currents, and nAChR; inhibits CaM cAMP PDE (IC50: 3.3 nM) and estrogen signaling.Formula:C30H32N4O6Purity:98%Color and Shape:SolidMolecular weight:544.6CK59
CAS:CK59 inhibits CaMKII and several voltage-gated calcium channels, with an IC50 of ~50 μM.Formula:C21H37N7O3Purity:98%Color and Shape:SolidMolecular weight:435.56Prenylamine lactate
CAS:Prenylamine lactate, an ex-angina drug, depletes heart catecholamines and blocks calcium channels.Formula:C27H33NO3Purity:98%Color and Shape:SolidMolecular weight:419.56W-5 hydrochloride
CAS:W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl) is a potent calmodulin antagonist.Formula:C16H23ClN2O2SPurity:99.35%Color and Shape:Off-White Crystalline SolidMolecular weight:342.88W-13 hydrochloride
CAS:W-13 hydrochloride (W-13 HCl) is a calmodulin antagonist.Formula:C14H18Cl2N2O2SPurity:98.51%Color and Shape:White PowderMolecular weight:349.28CV-159
CAS:CV-159 is a unique dihydropyridine Ca2+ antagonist with antiinflammatory activities. It has an anti-calmodulin (CaM) action.Formula:C31H34N4O7Purity:98%Color and Shape:SolidMolecular weight:574.62A-7 hydrochloride
CAS:A-7 hydrochloride is a calmodulin antagonist and causes alterations in the subpopulation of CD44+CD24- in MDA-MB-231 cells.
Formula:C20H30Cl2N2O2SPurity:99.38%Color and Shape:SolidMolecular weight:433.44TX-1123
CAS:TX-1123: PTK/COX inhibitor, Src/eEF2-K/PKA/EGFR-K/PKC targeted, IC50 of 1.16μM(COX2), 15.7μM(COX1), low mitochondrial toxicity.Formula:C20H24O3Color and Shape:SolidMolecular weight:312.4CBP501
CAS:CBP501 peptide inhibits kinases like MAPKAP-K2/C-Tak1/CHK1, preventing Cdc25C function and blocking the entry into mitosis.Formula:C86H122F5N29O17Color and Shape:SolidMolecular weight:1929.06Ph-HTBA
CAS:Ph-HTBA: high-affinity CaMKIIα modulator, brain-penetrant, Kd 757 nM, used in ischemia/neurodegeneration research.Formula:C19H18O3Color and Shape:SolidMolecular weight:294.34TIM-063
CAS:TIM-063: ATP-competitive CaMKKα/β inhibitor, cell-permeable, Ki: 0.35/0.2 μM, IC50: 0.63/0.96 μM.Formula:C18H9N3O4Color and Shape:SolidMolecular weight:331.28Bisindolylmaleimide VII
CAS:Bisindolylmaleimide VII is a selective inhibitor of protein kinase C.Formula:C27H27N5O2Color and Shape:SolidMolecular weight:453.54
