GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 255 products of "GluR"
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(±)-LY367385
CAS:<p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>Formula:C10H11NO4Color and Shape:SolidMolecular weight:209.201MPPG
CAS:<p>MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).</p>Formula:C9H12NO5PColor and Shape:SolidMolecular weight:245.171KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Formula:C22H12F3N5Na2O7Purity:97.27%Color and Shape:SoildMolecular weight:561.33LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formula:C25H31F2NO11SColor and Shape:SolidMolecular weight:591.58(S,S)-BMS-984923
CAS:<p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.</p>Formula:C22H15ClN2O2Color and Shape:SolidMolecular weight:374.82STX-107
CAS:<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Formula:C18H10FN3SPurity:99.17%Color and Shape:SolidMolecular weight:319.36JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Color and Shape:SolidLY2812223
CAS:<p>LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).</p>Formula:C10H12N4O4SPurity:98%Color and Shape:SolidMolecular weight:284.29MGS0274
CAS:<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Formula:C21H32FNO7Color and Shape:SolidMolecular weight:429.485ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Formula:C19H15FN2OPurity:99.98% - 99.98%Color and Shape:SoildMolecular weight:306.331H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Formula:C10H12N2O2SPurity:99.96%Color and Shape:SoildMolecular weight:224.28LY3020371
CAS:<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Formula:C15H15F2NO5SColor and Shape:SolidMolecular weight:359.34LY3027788 hydrochloride
CAS:<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Formula:C25H32ClF2NO11SColor and Shape:SolidMolecular weight:628.03(S)-3,4-DCPG
CAS:<p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>Formula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18MGS0028
CAS:<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Formula:C8H8FNO5Color and Shape:SolidMolecular weight:217.15L-AP3
CAS:<p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>Formula:C3H8NO5PColor and Shape:White Hygroscopic SolidMolecular weight:169.073(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Formula:C10H10ClNO6Purity:99.53% - 99.9%Color and Shape:SoildMolecular weight:275.64NS-102
CAS:<p>NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.</p>Formula:C12H11N3O4Purity:98.48% - 98.95%Color and Shape:SolidMolecular weight:261.23VU0422288
CAS:<p>VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.</p>Formula:C17H11Cl2N3O2Purity:95.48%Color and Shape:SolidMolecular weight:360.19VU0364770 hydrochloride
CAS:<p>VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).</p>Formula:C12H10Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:269.13
![1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT60224.webp&w=3840&q=75)
