GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 263 products for "GluR".
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MGS0274
CAS:MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.Formula:C21H32FNO7Color and Shape:SolidMolecular weight:429.485JF-NP-26
Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.Color and Shape:SolidLY3020371
CAS:LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.Formula:C15H15F2NO5SColor and Shape:SolidMolecular weight:359.34(±)-LY367385
CAS:(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.Formula:C10H11NO4Color and Shape:SolidMolecular weight:209.201L-AP3
CAS:L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).Formula:C3H8NO5PColor and Shape:SolidMolecular weight:169.073LY2812223
CAS:LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Formula:C10H12N4O4SPurity:98%Color and Shape:SolidMolecular weight:284.29LY3027788 hydrochloride
CAS:LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.Formula:C25H32ClF2NO11SColor and Shape:SolidMolecular weight:628.03mGluR1 activator-1
mGluR1activator-1 is a stable vitamin K analog and mGluR1 activator capable of crossing the blood-brain barrier. It strongly activates transcription through steroid and xenobiotic receptors and retinoic acid receptors, effectively inducing neurogenesis in neural progenitor cells in mice. mGluR1activator-1 is applicable in studying neurodegenerative diseases, such as Alzheimer's.Color and Shape:Odour Solid(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.Formula:C7H11ClN2O4Purity:99.18%Color and Shape:SolidMolecular weight:222.63MMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Formula:C19H16ClN3O3Purity:99.88%Color and Shape:Yellow SolidMolecular weight:369.8Ref: TM-T23008L
1mg56.00€5mg119.00€1mL*10mM (DMSO)133.00€10mg192.00€25mg394.00€50mg585.00€100mg833.00€200mg1,134.00€(S)-3,4-DCPG
CAS:(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Formula:C10H9NO6Purity:98%Color and Shape:SolidMolecular weight:239.18MPPG
CAS:MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).Formula:C9H12NO5PColor and Shape:SolidMolecular weight:245.171GYKI-47261 dihydrochloride
CAS:GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.Formula:C18H17Cl3N4Purity:98.32% - 99.14%Color and Shape:White SolidMolecular weight:395.711H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.Formula:C10H12N2O2SPurity:99.96%Color and Shape:Yellow SolidMolecular weight:224.28mGluR5 modulator 1
CAS:mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.Formula:C18H19ClFN3O2Color and Shape:SolidMolecular weight:363.82DL-AP4
CAS:DL-AP4, also known as 2-Amino-4-phosphonobutyric acid, is a competitive glutamate antagonist with defined binding affinity that is widely used to selectively inhibit glutamatergic neurotransmission, making it an essential experimental compound for probing synaptic signaling mechanisms and functional circuitry in central nervous system and visual system research.Formula:C4H10NO5PPurity:99.98%Color and Shape:White SolidMolecular weight:183.1LY3027788
CAS:LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.Formula:C25H31F2NO11SColor and Shape:SolidMolecular weight:591.58MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Formula:C8H8FNO5Color and Shape:SolidMolecular weight:217.15(S)-3,4-DCPG HCl
(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.Formula:C10H10ClNO6Purity:99.53% - 99.86%Color and Shape:SolidMolecular weight:275.64Ref: TM-T23288L
1mg173.00€1mL*10mM (DMSO)394.00€5mg437.00€10mg625.00€25mg982.00€50mg1,341.00€100mg1,773.00€500mg3,565.00€VU0364770 hydrochloride
CAS:VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).Formula:C12H10Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:269.13
![1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT60224.webp&w=3840&q=75)
