GluR
Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.
Found 266 products for "GluR".
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EGLU
CAS:EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.Formula:C7H13NO4Purity:98.18%Color and Shape:SolidMolecular weight:175.18γ-DGG
CAS:gamma-DGG is a competitive blocker of AMPA receptor.Formula:C7H12N2O5Purity:99.90%Color and Shape:SolidMolecular weight:204.18GYKI 53655 hydrochloride
CAS:GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.Formula:C19H21ClN4O3Purity:98.02%Color and Shape:SolidMolecular weight:388.85LY341495
CAS:LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological disorders.Formula:C20H19NO5Purity:98.53% - 99.37%Color and Shape:SolidMolecular weight:353.37Ro 01-6128
CAS:Positive allosteric modulator of mGlu1 receptorsFormula:C17H17NO3Purity:98%Color and Shape:SolidMolecular weight:283.32VU0080241
CAS:VU0080241 is an mGluR4 positive allosteric modulator (EC50=4.6 μM) that enhances glutamate-induced calcium influx.Formula:C19H23N5Purity:99.78%Color and Shape:SolidMolecular weight:321.4194AMN082
CAS:AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.Formula:C28H30Cl2N2Purity:97.13% - 98.63%Color and Shape:SolidMolecular weight:465.46GYKI 52466 dihydrochloride
CAS:GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.Formula:C17H17Cl2N3O2Purity:99.38%Color and Shape:Yellow SolidMolecular weight:366.24JNJ-46778212
CAS:JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.Formula:C20H17FN2O3Purity:99.79%Color and Shape:White SolidMolecular weight:352.36VU0422288
CAS:VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.Formula:C17H11Cl2N3O2Purity:99.77%Color and Shape:SolidMolecular weight:360.19NS-102
CAS:NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.Formula:C12H11N3O4Purity:97.96% - 98.95%Color and Shape:Yellow SolidMolecular weight:261.2334VU0364770 hydrochloride
CAS:VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).Formula:C12H10Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:269.127YM-298198 hydrochloride
CAS:YM-298198 hydrochloride is an orally active mGluR1 antagonist (Ki=19 nM) with analgesic effects in neurological disorder models.Formula:C18H23ClN4OSPurity:98%Color and Shape:SolidMolecular weight:378.919VU0361737
CAS:VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.Formula:C13H11ClN2O2Purity:99.60% - 99.85%Color and Shape:SolidMolecular weight:262.69CX614
CAS:CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.Formula:C13H13NO4Purity:97.37%Color and Shape:White SolidMolecular weight:247.25ADX-47273
CAS:ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).Formula:C20H17F2N3O2Purity:97% - 99.22%Color and Shape:White SolidMolecular weight:369.3647AZD-8529
CAS:AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.Formula:C24H24F3N5O3Color and Shape:SolidMolecular weight:487.4743NBQX
CAS:NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.Formula:C12H8N4O6SPurity:97.66% - 99.93%Color and Shape:SolidMolecular weight:336.28DNQX
CAS:DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)Formula:C8H4N4O6Purity:97.27% - 99.1%Color and Shape:White SolidMolecular weight:252.1406JNJ-40411813
CAS:JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).Formula:C20H25ClN2OPurity:99.74%Color and Shape:SolidMolecular weight:344.878
