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GluR

GluR

Glutamate Receptor inhibitors are compounds that block the activity of glutamate receptors, which are the main excitatory neurotransmitter receptors in the brain. These receptors play a pivotal role in synaptic transmission, plasticity, learning, and memory. Dysregulation of glutamate signaling is associated with various neurological disorders, including epilepsy, stroke, and neurodegenerative diseases. GluR inhibitors are essential for investigating the mechanisms of excitotoxicity and developing neuroprotective strategies. At CymitQuimica, we offer a range of glutamate receptor inhibitors to support your research in synaptic function, neuroprotection, and cognitive disorders.

Found 255 products of "GluR"

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  • LY341495
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    LY341495

    CAS:
    <p>LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological disorders.</p>
    Formula:C20H19NO5
    Purity:98.53% - 99.37%
    Color and Shape:Solid
    Molecular weight:353.37

    Ref: TM-T15816

  • GYKI 53655 hydrochloride
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    GYKI 53655 hydrochloride

    CAS:
    <p>GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.</p>
    Formula:C19H21ClN4O3
    Purity:98.02%
    Color and Shape:Solid
    Molecular weight:388.85

    Ref: TM-T15456

  • JNJ-46778212
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    JNJ-46778212

    CAS:
    <p>JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.</p>
    Formula:C20H17FN2O3
    Purity:99.24%
    Color and Shape:Solid
    Molecular weight:352.36

    Ref: TM-T15619

  • GYKI 52466 dihydrochloride
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    GYKI 52466 dihydrochloride

    CAS:
    <p>GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.</p>
    Formula:C17H17Cl2N3O2
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:366.24

    Ref: TM-T11522

  • γ-DGG
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    γ-DGG

    CAS:
    <p>gamma-DGG is a competitive blocker of AMPA receptor.</p>
    Formula:C7H12N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:204.18

    Ref: TM-T15369

  • VU0364770 hydrochloride
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    VU0364770 hydrochloride

    CAS:
    <p>VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).</p>
    Formula:C12H10Cl2N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:269.13

    Ref: TM-T13317

  • Ro 01-6128
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    Ro 01-6128

    CAS:
    <p>Positive allosteric modulator of mGlu1 receptors</p>
    Formula:C17H17NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:283.32

    Ref: TM-T23238

  • VU0422288
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    VU0422288

    CAS:
    <p>VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.</p>
    Formula:C17H11Cl2N3O2
    Purity:95.48%
    Color and Shape:Solid
    Molecular weight:360.19

    Ref: TM-T29135

  • AMN082
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    AMN082

    CAS:
    <p>AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.</p>
    Formula:C28H30Cl2N2
    Purity:97.13% - 98.63%
    Color and Shape:Solid
    Molecular weight:465.46

    Ref: TM-T21935

  • CFMTI
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    CFMTI

    CAS:
    <p>CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.</p>
    Formula:C19H16FN5O
    Purity:97.23%
    Color and Shape:Solid
    Molecular weight:349.36

    Ref: TM-T3482

  • (S)-ATPO
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    (S)-ATPO

    CAS:
    <p>(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.</p>
    Formula:C11H19N2O7P
    Purity:98.37% - 99.41%
    Color and Shape:Solid
    Molecular weight:322.25

    Ref: TM-T3473

  • MTEP
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    MTEP

    CAS:
    <p>MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.</p>
    Formula:C11H8N2S
    Color and Shape:Solid
    Molecular weight:200.26

    Ref: TM-T73568

  • Ro0711401
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    Ro0711401

    CAS:
    <p>Ro0711401 is an agonist of mGlu1 receptor.</p>
    Formula:C18H11F3N2O3
    Purity:97.57%
    Color and Shape:Solid
    Molecular weight:360.29

    Ref: TM-T9021

  • DNQX
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    DNQX

    CAS:
    <p>DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)</p>
    Formula:C8H4N4O6
    Purity:97.27% - 99.1%
    Color and Shape:Off-White Powder With A Yellow Tinge
    Molecular weight:252.14

    Ref: TM-T7304

  • VU0155041
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    VU0155041

    CAS:
    <p>VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).</p>
    Formula:C14H15Cl2NO3
    Purity:99.52% - 99.56%
    Color and Shape:Solid
    Molecular weight:316.18

    Ref: TM-T3565

  • VU0361737
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    VU0361737

    CAS:
    <p>VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.</p>
    Formula:C13H11ClN2O2
    Purity:99.60% - 99.85%
    Color and Shape:Solid
    Molecular weight:262.69

    Ref: TM-T6726

  • ADX88178
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    ADX88178

    CAS:
    <p>ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.</p>
    Formula:C12H12N6S
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:272.33

    Ref: TM-T4500

  • JNJ-40411813
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    JNJ-40411813

    CAS:
    <p>JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).</p>
    Formula:C20H25ClN2O
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:344.88

    Ref: TM-TQ0094

  • CX614
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    CX614

    CAS:
    <p>CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.</p>
    Formula:C13H13NO4
    Purity:97.37%
    Color and Shape:Solid
    Molecular weight:247.25

    Ref: TM-T19698

  • ADX-47273
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    ADX-47273

    CAS:
    <p>ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).</p>
    Formula:C20H17F2N3O2
    Purity:97% - 99.18%
    Color and Shape:Solid
    Molecular weight:369.36

    Ref: TM-T2053