BACE
BACE inhibitors are compounds that target the Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), which is crucial for the production of beta-amyloid, a protein associated with the formation of amyloid plaques in Alzheimer's disease. By inhibiting BACE, these compounds aim to reduce the production of beta-amyloid and its accumulation in the brain, potentially slowing the progression of Alzheimer's disease. BACE inhibitors are a major focus in the development of therapeutic strategies for neurodegenerative diseases. At CymitQuimica, we offer BACE inhibitors to support your research in Alzheimer's disease, amyloid biology, and neurodegeneration.
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Elenbecestat
CAS:1388651-30-6
Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment …
Formula:
C19H18F3N5O2S
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
437.44
Ref: TM-T11175
| 1mg | 71.00 € | ||
| 5mg | 153.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 519.00 € | ||
| 50mg | 749.00 € | ||
| 100mg | 1,025.00 € | ||
| 1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
SEW06622
CAS:261349-28-4
SEW06622 is a inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate …
Formula:
C21H26N2O2
Purity:
99.87%
Color and Shape:
Soild
Molecular weight:
338.44
Ref: TM-T83616
| 1mg | 182.00 € | ||
| 5mg | 449.00 € | ||
| 10mg | 643.00 € | ||
| 25mg | 1,004.00 € | ||
| 50mg | 1,385.00 € | ||
| 100mg | 1,831.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Epiberberine chloride
CAS:889665-86-5
Epiberberine chloride, a natural pro-berberine from Coptis chinensis Franch. is an AChE, BChE, and BACE1 …
Formula:
C20H18ClNO4
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
371.81
Ref: TM-T8306
| 1mg | 38.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 281.00 € | ||
| 100mg | 417.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
BACE1 Protein, Human, Recombinant (His)
BACE1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Color and Shape:
Liquid
Molecular weight:
49.9 kDa (predicted)
Ref: TM-TMPY-00752
| 1mg | 3,727.00 € | ||
| 100µg | 591.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
BACE1 Protein, Human, Recombinant
BACE1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is …
Color and Shape:
Liquid
Molecular weight:
49 kDa (predicted)
Ref: TM-TMPY-00652
| 100µg | 589.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
BACE1 Protein, Human, Recombinant (hFc)
BACE1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.
Color and Shape:
Solid
Molecular weight:
75 kDa (predicted)
Ref: TM-TMPY-00651
| 1mg | 3,727.00 € | ||
| 100µg | 591.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Aloeresin D
CAS:105317-67-7
Aloeresin D, a natural chromone glycoside, inhibits β-Secretase (BACE1) activity (IC50: 39 μM).
Formula:
C29H32O11
Purity:
98.11% - 99.57%
Color and Shape:
Solid
Molecular weight:
556.56
Ref: TM-T8179
| 1mg | 60.00 € | ||
| 5mg | 138.00 € | ||
| 10mg | 212.00 € | ||
| 25mg | 361.00 € | ||
| 50mg | 531.00 € | ||
| 100mg | 755.00 € | ||
| 1mL*10mM (DMSO) | 176.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Verubecestat
CAS:1286770-55-5
Verubecestat (MK-8931) (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 …
Formula:
C17H17F2N5O3S
Purity:
99.49% - ≥98%
Color and Shape:
Solid
Molecular weight:
409.41
Ref: TM-T7011
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 149.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 346.00 € | ||
| 500mg | 810.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Phytic acid potassium
CAS:129832-03-7
Phytic acid potassium (Inositol polyphosphate dipotassium salt) is an endogenous metabolite present in all eukaryotic …
Formula:
C6H16K2O24P6
Purity:
98% - ≥98%
Color and Shape:
Solid
Molecular weight:
736.22
Ref: TM-T5075
| 1g | 65.00 € | ||
| 5g | 140.00 € | ||
| 500mg | 48.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tenuifolin
CAS:20183-47-5
Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the …
Formula:
C36H56O12
Purity:
97.37% - 99.9%
Color and Shape:
Solid
Molecular weight:
680.82
Ref: TM-T3769
| 5mg | 48.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 140.00 € | ||
| 50mg | 194.00 € | ||
| 100mg | 293.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY2811376
CAS:1194044-20-6
LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: …
Formula:
C15H14F2N4S
Purity:
99% - 99.01%
Color and Shape:
Solid
Molecular weight:
320.36
Ref: TM-T2639
| 1mg | 52.00 € | ||
| 2mg | 78.00 € | ||
| 5mg | 126.00 € | ||
| 10mg | 207.00 € | ||
| 25mg | 370.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 786.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Epiberberine
CAS:6873-09-2
1.
Formula:
C20H18NO4
Purity:
98.52% - 99.59%
Color and Shape:
Solid
Molecular weight:
336.36
Ref: TM-T5S2361
| 1mg | 36.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 478.00 € | ||
| 500mg | 1,068.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY2886721
CAS:1262036-50-9
LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.
Formula:
C18H16F2N4O2S
Purity:
99% - 99.94%
Color and Shape:
Solid
Molecular weight:
390.41
Ref: TM-T6058
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 134.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 338.00 € | ||
| 200mg | 481.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Aloenin
CAS:38412-46-3
1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH …
Formula:
C19H22O10
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
410.37
Ref: TM-T2S1181
| 2mg | 45.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | To inquire | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Scoulerine
CAS:6451-73-6
Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).
Formula:
C19H21NO4
Purity:
99.22%
Color and Shape:
Solid
Molecular weight:
327.37
Ref: TM-TN2190
| 1mg | 52.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 454.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Eslicarbazepine Acetate
CAS:236395-14-5
Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for …
Formula:
C17H16N2O3
Purity:
100% - 99.59%
Color and Shape:
White To Off-White Solid
Molecular weight:
296.32
Ref: TM-T3285
| 5mg | 38.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 123.00 € | ||
| 100mg | 168.00 € | ||
| 200mg | 265.00 € | ||
| 500mg | 388.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sophoflavescenol
CAS:216450-65-6
Sophoflavescenol: PDE5 inhibitor (K(i) 0.005 µM), antioxidant, anti-inflammatory, pro-apoptotic, potential antitumor, mild side effects.
Formula:
C21H20O6
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
368.38
Ref: TM-TN2217
| 5mg | 620.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LX2343
CAS:333745-53-2
LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy …
Formula:
C22H19ClN2O6S
Purity:
99.92%
Color and Shape:
Solid
Molecular weight:
474.91
Ref: TM-T4398
| 2mg | 36.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 328.00 € | ||
| 200mg | 456.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD3839 free base
CAS:1227163-84-9
AZD3839 free base is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, …
Formula:
C24H16F3N5
Purity:
99.93% - 99.96%
Color and Shape:
Solid
Molecular weight:
431.41
Ref: TM-T6772
| 1mg | 52.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Atabecestat
CAS:1200493-78-2
Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and …
Formula:
C18H14FN5OS
Purity:
98.49% - 99.77%
Color and Shape:
Solid
Molecular weight:
367.4
Ref: TM-T14338
| 1mg | 127.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 491.00 € | ||
| 25mg | 983.00 € | ||
| 50mg | 1,317.00 € | ||
| 100mg | 1,780.00 € | ||
| 1mL*10mM (DMSO) | 343.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
