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BACE

BACE

BACE inhibitors are compounds that target the Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), which is crucial for the production of beta-amyloid, a protein associated with the formation of amyloid plaques in Alzheimer's disease. By inhibiting BACE, these compounds aim to reduce the production of beta-amyloid and its accumulation in the brain, potentially slowing the progression of Alzheimer's disease. BACE inhibitors are a major focus in the development of therapeutic strategies for neurodegenerative diseases. At CymitQuimica, we offer BACE inhibitors to support your research in Alzheimer's disease, amyloid biology, and neurodegeneration.

Found 36 products of "BACE"

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  • Elenbecestat

    CAS:
    Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.
    Formula:C19H18F3N5O2S
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:437.44

    Ref: TM-T11175

    1mg
    66.00€
    5mg
    144.00€
    10mg
    236.00€
    25mg
    492.00€
    50mg
    710.00€
    100mg
    973.00€
    1mL*10mM (DMSO)
    158.00€
  • BACE1 Protein, Human, Recombinant (hFc)


    BACE1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.
    Color and Shape:Lyophilized Powder
    Molecular weight:75.2 kDa (predicted, pro-form); 72.6 kDa (predicted, mature-form); 85-100 kDa (reducing condition, due to glycosylation)

    Ref: TM-TMPY-00651

    1mg
    4,440.00€
    5µg
    80.00€
    10µg
    115.00€
    20µg
    184.00€
    50µg
    370.00€
    100µg
    705.00€
    200µg
    1,074.00€
    500µg
    2,186.00€
  • Anti-BACE1 Antibody-FITC (8D358)


    Anti-BACE1 Antibody-FITC (8D358) is a FITC-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-FITC (8D358) can be used in FCM.
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-00206F

    25T
    110.00€
    100T
    216.00€
  • Anti-BACE1 Antibody-PE (8D358)


    Anti-BACE1 Antibody-PE (8D358) is a PE-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-PE (8D358) can be used in FCM.
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-00206P

    25T
    136.00€
    100T
    265.00€
  • Anti-BACE1 Antibody (2Z488)


    Anti-BACE1 Antibody (2Z488) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (2Z488) can be used in ELISA.
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-00207

    100µl
    204.00€
  • Anti-BACE1 Antibody (2J206)


    Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA, WB.
    Color and Shape:Odour Liquid

    Ref: TM-TMAH-00101

    50µl
    215.00€
    100µl
    359.00€
  • Anti-BACE1 Antibody (8A762)


    Anti-BACE1 Antibody (8A762) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (8A762) can be used in ELISA.
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-00205

    100µl
    277.00€
  • Anti-BACE1 Antibody (3R945)


    Anti-BACE1 Antibody (3R945) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (3R945) can be used in ELISA.
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-00204

    100µl
    205.00€
  • Anti-BACE1 Antibody (8D358)


    Anti-BACE1 Antibody (8D358) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (8D358) can be used in FCM,ICC/IF.
    Color and Shape:Odour Liquid

    Ref: TM-TMAY-00206

    100µl
    276.00€
  • BACE1 Protein, Human, Recombinant


    BACE1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 49 kDa and the accession number is A0A024R3D7.
    Color and Shape:Lyophilized Powder
    Molecular weight:49 kDa (predicted); 65 kDa (reducing condition, due to glycosylation)

    Ref: TM-TMPY-00652

    5µg
    80.00€
    10µg
    115.00€
    20µg
    184.00€
    50µg
    370.00€
    100µg
    705.00€
  • BACE1 Protein, Human, Recombinant (His)


    BACE1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
    Color and Shape:Lyophilized Powder
    Molecular weight:49.5 kDa (predicted); 55-70 kDa (reducing condition, due to glycosylation)

    Ref: TM-TMPY-00752

    1mg
    3,215.00€
    5µg
    80.00€
    10µg
    116.00€
    20µg
    177.00€
    50µg
    353.00€
    100µg
    690.00€
    200µg
    960.00€
    500µg
    1,686.00€
  • Verubecestat

    CAS:
    Verubecestat (MK-8931) (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 inhibitor or BACE1 protein inhibitor.
    Formula:C17H17F2N5O3S
    Purity:94.64% - 99.55%
    Color and Shape:Solid
    Molecular weight:409.41

    Ref: TM-T7011

    2mg
    40.00€
    5mg
    60.00€
    10mg
    88.00€
    25mg
    153.00€
    50mg
    216.00€
    100mg
    354.00€
    500mg
    825.00€
    1mL*10mM (DMSO)
    66.00€
  • LY2811376

    CAS:
    LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM).
    Formula:C15H14F2N4S
    Purity:99% - 99.01%
    Color and Shape:Solid
    Molecular weight:320.36

    Ref: TM-T2639

    1mg
    52.00€
    2mg
    73.00€
    5mg
    123.00€
    10mg
    205.00€
    25mg
    374.00€
    50mg
    560.00€
    100mg
    800.00€
    1mL*10mM (DMSO)
    123.00€
  • BACE-IN-1 acetate


    BACE-IN-1 acetate (350228-37-4), a BACE1 inhibitor with three disulfide bonds and N-linked glycosylation, is used in assays.
    Formula:C75H122N16O29
    Purity:96.98%
    Color and Shape:Solid
    Molecular weight:1711.86

    Ref: TM-T3161L

    1mg
    145.00€
    5mg
    319.00€
    10mg
    472.00€
    25mg
    753.00€
    50mg
    1,074.00€
  • Sophoflavescenol

    CAS:
    Sophoflavescenol: PDE5 inhibitor (K(i) 0.005 µM), antioxidant, anti-inflammatory, pro-apoptotic, potential antitumor, mild side effects.
    Formula:C21H20O6
    Purity:99.65%
    Color and Shape:Solid
    Molecular weight:368.38

    Ref: TM-TN2217

    5mg
    625.00€
  • LX2343

    CAS:
    LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.
    Formula:C22H19ClN2O6S
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:474.91

    Ref: TM-T4398

    2mg
    37.00€
    5mg
    52.00€
    10mg
    84.00€
    25mg
    137.00€
    50mg
    229.00€
    100mg
    340.00€
    200mg
    472.00€
    1mL*10mM (DMSO)
    58.00€
  • AZD3839 free base

    CAS:
    AZD3839 free base is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.
    Formula:C24H16F3N5
    Purity:99.93% - 99.96%
    Color and Shape:Solid
    Molecular weight:431.41

    Ref: TM-T6772

    1mg
    90.00€
    5mg
    187.00€
    10mg
    310.00€
    25mg
    520.00€
    50mg
    740.00€
    1mL*10mM (DMSO)
    210.00€
  • Epiberberine

    CAS:
    1.
    Formula:C20H18NO4
    Purity:98.52% - 99.59%
    Color and Shape:Solid
    Molecular weight:336.36

    Ref: TM-T5S2361

    1mg
    37.00€
    5mg
    79.00€
    10mg
    96.00€
    25mg
    183.00€
    50mg
    344.00€
    100mg
    485.00€
    500mg
    1,093.00€
  • LY2886721

    CAS:
    <p>LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.</p>
    Formula:C18H16F2N4O2S
    Purity:99% - 99.75%
    Color and Shape:Solid
    Molecular weight:390.41

    Ref: TM-T6058

    5mg
    50.00€
    10mg
    80.00€
    25mg
    138.00€
    50mg
    235.00€
    100mg
    350.00€
    200mg
    499.00€
  • Aloenin

    CAS:
    <p>1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro.</p>
    Formula:C19H22O10
    Purity:99.42% - 99.69%
    Color and Shape:Solid
    Molecular weight:410.37

    Ref: TM-T2S1181

    2mg
    46.00€
    5mg
    88.00€
    10mg
    127.00€
    25mg
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