BACE
BACE inhibitors are compounds that target the Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), which is crucial for the production of beta-amyloid, a protein associated with the formation of amyloid plaques in Alzheimer's disease. By inhibiting BACE, these compounds aim to reduce the production of beta-amyloid and its accumulation in the brain, potentially slowing the progression of Alzheimer's disease. BACE inhibitors are a major focus in the development of therapeutic strategies for neurodegenerative diseases. At CymitQuimica, we offer BACE inhibitors to support your research in Alzheimer's disease, amyloid biology, and neurodegeneration.
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Lanabecestat
CAS:1383982-64-6
Lanabecestat (AZD3293) is a BACE1 inhibitor (Ki: 0.4 nM), Lanabecestat is used in the study …
Formula:
C26H28N4O
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
412.53
Ref: TM-TQ0238
| 1mg | 144.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
BACE1-IN-1
CAS:1310347-50-2
BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human …
Formula:
C18H14F3N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
389.33
Ref: TM-T10450
| 25mg | 1,531.00 € | ||
| 50mg | 2,003.00 € | ||
| 100mg | 2,888.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
NB-360
CAS:1262857-73-7
NB-360: potent, brain-penetrant BACE1/2 inhibitor; IC50s: 5-6 nM; high selectivity vs pepsin, cathepsin E/D.
Formula:
C21H19F4N5O2
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
449.4
Ref: TM-T12188
| 1mg | 108.00 € | ||
| 5mg | 221.00 € | ||
| 10mg | 328.00 € | ||
| 25mg | 527.00 € | ||
| 50mg | 713.00 € | ||
| 100mg | 917.00 € | ||
| 500mg | 1,838.00 € | ||
| 1mL*10mM (DMSO) | 248.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
BACE1-IN-2
CAS:1352416-78-4
BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).
Formula:
C19H15F4N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
421.35
Ref: TM-T10451
| 25mg | 2,377.00 € | ||
| 50mg | 3,149.00 € | ||
| 100mg | 4,285.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
Umibecestat
CAS:1387560-01-1
Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM & 10 nM), potentially for Alzheimer's …
Formula:
C19H15ClF7N5O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
513.8
Ref: TM-T13253
| 1mg | 169.00 € | ||
| 5mg | 346.00 € | ||
| 10mg | 500.00 € | ||
| 25mg | 832.00 € | ||
| 50mg | 1,133.00 € | ||
| 100mg | 1,538.00 € | ||
| 1mL*10mM (DMSO) | 423.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
PF-06751979
CAS:1818339-66-0
PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of …
Formula:
C18H19F2N5O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
455.5
Ref: TM-T12429
| 25mg | 1,141.00 € | ||
| 50mg | 1,507.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
BACE1-IN-4
CAS:2361157-92-6
BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), …
Formula:
C21H23F2N5O4S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
511.57
Ref: TM-T10452
| 25mg | 2,662.00 € | ||
| 50mg | 3,533.00 € | ||
| 100mg | 4,860.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
AM-6494
CAS:1874232-80-0
AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo …
Formula:
C22H21F2N5O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
473.5
Ref: TM-T10292
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Monday 3 Mar 2025
