BACE
BACE inhibitors are compounds that target the Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), which is crucial for the production of beta-amyloid, a protein associated with the formation of amyloid plaques in Alzheimer's disease. By inhibiting BACE, these compounds aim to reduce the production of beta-amyloid and its accumulation in the brain, potentially slowing the progression of Alzheimer's disease. BACE inhibitors are a major focus in the development of therapeutic strategies for neurodegenerative diseases. At CymitQuimica, we offer BACE inhibitors to support your research in Alzheimer's disease, amyloid biology, and neurodegeneration.
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Scoulerine
CAS:6451-73-6
Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).
Formula:
C19H21NO4
Purity:
99.22%
Color and Shape:
Solid
Molecular weight:
327.37
Ref: TM-TN2190
| 1mg | 52.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 465.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Eslicarbazepine Acetate
CAS:236395-14-5
Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for …
Formula:
C17H16N2O3
Purity:
100% - 99.58%
Color and Shape:
White To Off-White Solid
Molecular weight:
296.32
Ref: TM-T3285
| 5mg | 38.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 124.00 € | ||
| 100mg | 170.00 € | ||
| 200mg | 268.00 € | ||
| 500mg | 393.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 22 Apr 2025
Atabecestat
CAS:1200493-78-2
Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and …
Formula:
C18H14FN5OS
Purity:
98.49% - 99.77%
Color and Shape:
Solid
Molecular weight:
367.4
Ref: TM-T14338
| 1mg | 130.00 € | ||
| 5mg | 311.00 € | ||
| 10mg | 502.00 € | ||
| 25mg | 1,008.00 € | ||
| 50mg | 1,349.00 € | ||
| 100mg | 1,825.00 € | ||
| 1mL*10mM (DMSO) | 344.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
Lanabecestat
CAS:1383982-64-6
Lanabecestat (AZD3293) is a BACE1 inhibitor (Ki: 0.4 nM), Lanabecestat is used in the study …
Formula:
C26H28N4O
Purity:
98.55%
Color and Shape:
Solid
Molecular weight:
412.53
Ref: TM-TQ0238
| 1mg | 146.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
BACE1-IN-1
CAS:1310347-50-2
BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human …
Formula:
C18H14F3N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
389.33
Ref: TM-T10450
| 25mg | 1,568.00 € | ||
| 50mg | 2,043.00 € | ||
| 100mg | 2,945.00 € |
Estimated delivery in United States, on Tuesday 17 Jun 2025
Umibecestat
CAS:1387560-01-1
Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM & 10 nM), potentially for Alzheimer's …
Formula:
C19H15ClF7N5O2
Purity:
100%
Color and Shape:
Solid
Molecular weight:
513.8
Ref: TM-T13253
| 1mg | 172.00 € | ||
| 5mg | 354.00 € | ||
| 10mg | 512.00 € | ||
| 25mg | 852.00 € | ||
| 50mg | 1,159.00 € | ||
| 100mg | 1,568.00 € | ||
| 1mL*10mM (DMSO) | 432.00 € |
Estimated delivery in United States, on Tuesday 15 Jul 2025
NB-360
CAS:1262857-73-7
NB-360: potent, brain-penetrant BACE1/2 inhibitor; IC50s: 5-6 nM; high selectivity vs pepsin, cathepsin E/D.
Formula:
C21H19F4N5O2
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
449.4
Ref: TM-T12188
| 1mg | 110.00 € | ||
| 5mg | 226.00 € | ||
| 10mg | 335.00 € | ||
| 25mg | 538.00 € | ||
| 50mg | 730.00 € | ||
| 100mg | 938.00 € | ||
| 500mg | 1,882.00 € | ||
| 1mL*10mM (DMSO) | 249.00 € |
Estimated delivery in United States, on Tuesday 15 Jul 2025
PF-06751979
CAS:1818339-66-0
PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of …
Formula:
C18H19F2N5O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
455.5
Ref: TM-T12429
| 25mg | 1,169.00 € | ||
| 50mg | 1,529.00 € |
Estimated delivery in United States, on Tuesday 15 Jul 2025
BACE1-IN-2
CAS:1352416-78-4
BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).
Formula:
C19H15F4N5O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
421.35
Ref: TM-T10451
| 25mg | 3,107.00 € | ||
| 50mg | 3,876.00 € | ||
| 100mg | 5,035.00 € |
Estimated delivery in United States, on Tuesday 15 Jul 2025
BACE1-IN-4
CAS:2361157-92-6
BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), …
Formula:
C21H23F2N5O4S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
511.57
Ref: TM-T10452
| 25mg | 3,107.00 € | ||
| 50mg | 3,876.00 € | ||
| 100mg | 5,035.00 € |
Estimated delivery in United States, on Tuesday 15 Jul 2025
AM-6494
CAS:1874232-80-0
AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo …
Formula:
C22H21F2N5O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
473.5
Ref: TM-T10292
| 25mg | 3,820.00 € | ||
| 50mg | 4,826.00 € | ||
| 100mg | 6,460.00 € |
Estimated delivery in United States, on Tuesday 15 Jul 2025
