AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 645 products of "AChR"
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Glycerophosphoinositol choline
CAS:Glycerophosphoinositol choline is the salt of choline and glycerophosphoinositol.Formula:C14H32NO12PColor and Shape:SolidMolecular weight:437.38Cevimeline hydrochloride
CAS:Cevimeline HCl is a muscarinic agonist enhancing salivary and sweat gland secretion.Formula:C10H18ClOSColor and Shape:SolidMolecular weight:235.77ABT-107
CAS:ABT-107: α7 neuronal receptor agonist; protects rats' brains from 6-OHDA-induced damage.Formula:C19H20N4OColor and Shape:SolidMolecular weight:320.396NSC 23766
CAS:NSC 23766 is a Rac1 GTPase inhibitor by targeting GEFs, inhibiting cell proliferation.NSC23766 competitively inhibits M2 mAChR-induced Rac1 activation.Formula:C24H35N7Purity:99.49%Color and Shape:SolidMolecular weight:421.58(±)-Darifenacin
CAS:(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.Formula:C28H30N2O2Color and Shape:SolidMolecular weight:426.55VU0467485
CAS:VU0467485 boosts ACh at M4 receptors (EC50: 26.6 nM rat, 78.8 nM human), selective for M4 over M1/2/3/5.Formula:C17H17FN4O2SPurity:98%Color and Shape:SolidMolecular weight:360.41Cevimeline
CAS:Cevimeline: muscarinic agonist, treats dry mouth & Sjögren's, boosts saliva post-cancer radiotherapy.Formula:C10H17NOSColor and Shape:Off-White SolidMolecular weight:199.31Clorprenaline
CAS:Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.Formula:C11H16ClNOPurity:98.9%Color and Shape:SolidMolecular weight:213.7Dibucaine hydrochloride
CAS:Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.Formula:C20H30ClN3O2Purity:99.66%Color and Shape:White PowderMolecular weight:379.92Pirmenol hydrochloride
CAS:Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μMFormula:C22H31ClN2OColor and Shape:SolidMolecular weight:374.95Tebanicline dihydrochloride
CAS:Tebanicline dihydrochloride: oral analgesic, nAChR modulator, Ki=37 pM at α4β2 receptors, inhibits cytisine binding.Formula:C9H13Cl3N2OColor and Shape:SolidMolecular weight:271.57Sabcomeline hydrochloride
CAS:Sabcomeline is a selective M1 receptor partial agonist.Formula:C10H16ClN3OColor and Shape:SolidMolecular weight:229.71NS3861 fumarate
CAS:NS3861 fumarate, a partial α3β4 nAChR agonist, binds α3β2, α4β4, α4β2 with Ki values of 0.62, 25, 7.8, 55 nM.Formula:C16H18BrNO4SColor and Shape:SolidMolecular weight:400.29DL-Cystine
CAS:DL-Cystine is a cysteine derivative that inhibits endothelial cell proliferation by regulating TGFβ1. a GPR inhibitor and nAChR agonist .Formula:C6H12N2O4S2Color and Shape:SolidMolecular weight:240.3Tebanicline hydrochloride
CAS:Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.Formula:C9H12Cl2N2OPurity:91.74% - 98.78%Color and Shape:SolidMolecular weight:235.11Procyclidine hydrochloride
CAS:Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.Formula:C19H30ClNOPurity:99.24% - 99.88%Color and Shape:Crystals From Petroleum Ether White PowderMolecular weight:323.9VU0119498
CAS:VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.Formula:C15H10BrNO2Purity:97.56%Color and Shape:SolidMolecular weight:316.15VU0152100
CAS:VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).Formula:C18H19N3O2SPurity:99.56%Color and Shape:SolidMolecular weight:341.43Ref: TM-T17238
2mg39.00€5mg58.00€10mg92.00€25mg195.00€50mg325.00€100mg522.00€200mg743.00€1mL*10mM (DMSO)64.00€Nitrobenzylthioinosine
CAS:Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.Formula:C17H17N5O6SPurity:99.69% - 99.74%Color and Shape:Off-White SolidMolecular weight:419.41Harman hydrochloride
CAS:Harman hydrochloride triggers CYP1A1 gene via AhR, potentially causing mutations and cancer.Formula:C12H11ClN2Purity:99.35%Color and Shape:SolidMolecular weight:218.68
