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AChR

AChR

Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.

Found 574 products of "AChR"

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  • BNC210
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    BNC210

    CAS:
    <p>BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.</p>
    Formula:C17H23N3O3
    Purity:97.05% - >99.99%
    Color and Shape:Solid
    Molecular weight:317.38

    Ref: TM-T8318

  • Prifinium bromide
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    Prifinium bromide

    CAS:
    <p>Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract and has a spasmolytic action.</p>
    Formula:C22H28BrN
    Purity:97.99%
    Color and Shape:Solid
    Molecular weight:386.37

    Ref: TM-T9420

  • Nor-benzetimide
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    Nor-benzetimide

    CAS:
    <p>Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.</p>
    Formula:C16H20N2O2
    Purity:98.63%
    Color and Shape:Solid
    Molecular weight:272.34

    Ref: TM-T22380

  • NS 1738
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    NS 1738

    CAS:
    <p>NS 1738 (NSC-213859) is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)</p>
    Formula:C14H9Cl2F3N2O2
    Purity:99.11%
    Color and Shape:Solid
    Molecular weight:365.13

    Ref: TM-T7884

  • Cyclodrine hydrochloride
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    Cyclodrine hydrochloride

    CAS:
    <p>Cyclodrine hydrochloride is a dual cholinergic muscarinic receptor (mAChR) and nicotinic receptor (nAChR) antagonist that can be used in the study of</p>
    Formula:C19H30ClNO3
    Purity:98.59%
    Color and Shape:Solid
    Molecular weight:355.9

    Ref: TM-T10914

  • Pozanicline dihydrochloride
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    Pozanicline dihydrochloride

    CAS:
    <p>Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM)</p>
    Formula:C11H18Cl2N2O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:265.18

    Ref: TM-T12525

  • (-)-(S)-B-973B
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    (-)-(S)-B-973B

    CAS:
    <p>(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.</p>
    Formula:C24H26F2N6O
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:452.5

    Ref: TM-T17300

  • ST034307
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    ST034307

    CAS:
    <p>ST034307 is an effective and selective inhibitor of adenylyl cyclase 1 (IC50: 2.3 μM).</p>
    Formula:C10H4Cl4O2
    Purity:99.28%
    Color and Shape:Solid
    Molecular weight:297.95

    Ref: TM-T16938

  • Oxyphenonium bromide
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    Oxyphenonium bromide

    CAS:
    <p>Oxyphenonium bromide is an anticholinergic used to study and treat ulcers and relieve visceral spasms.</p>
    Formula:C21H34BrNO3
    Purity:98.96%
    Color and Shape:Solid
    Molecular weight:428.404

    Ref: TM-T33846

  • Umeclidinium bromide
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    Umeclidinium bromide

    CAS:
    <p>Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist.</p>
    Formula:C29H34BrNO2
    Purity:98.4% - 99.89%
    Color and Shape:Solid
    Molecular weight:508.49

    Ref: TM-T4997

  • Nitrobenzylthioinosine
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    Nitrobenzylthioinosine

    CAS:
    <p>Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.</p>
    Formula:C17H17N5O6S
    Purity:99.69% - 99.74%
    Color and Shape:Off-White Solid
    Molecular weight:419.41

    Ref: TM-T8551

  • PHA 568487 free base
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    PHA 568487 free base

    CAS:
    <p>PHA 568487 free base, an α7 nicotinic receptor agonist, designed to reduce bioactivation and improve in vivo tolerability.</p>
    Formula:C16H20N2O3
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:288.34

    Ref: TM-T23146

  • mAChR-IN-1 hydrochloride
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    mAChR-IN-1 hydrochloride

    CAS:
    <p>mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.</p>
    Formula:C23H26ClIN2O2
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:524.82

    Ref: TM-T5655

  • NS9283
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    NS9283

    CAS:
    <p>NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.</p>
    Formula:C14H8N4O
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:248.24

    Ref: TM-T28199

  • PNU-120596
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    PNU-120596

    CAS:
    <p>PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.</p>
    Formula:C13H14ClN3O4
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:311.72

    Ref: TM-T6950

  • MC-Val-Cit-PABC-PNP
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    MC-Val-Cit-PABC-PNP

    CAS:
    <p>MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker.</p>
    Formula:C35H43N7O11
    Purity:97.2% - 98.055%
    Color and Shape:Solid
    Molecular weight:737.76

    Ref: TM-T3503

  • Ethyl (triphenylphosphoranylidene) acetate
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    Ethyl (triphenylphosphoranylidene) acetate

    CAS:
    <p>Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.</p>
    Formula:C22H21O2P
    Purity:97.985%
    Color and Shape:White Or Slight Yellow Powder
    Molecular weight:348.37

    Ref: TM-T22329

  • Blarcamesine
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    Blarcamesine

    CAS:
    <p>Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.</p>
    Formula:C19H23NO
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:281.39

    Ref: TM-T7780

  • Encenicline hydrochloride
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    Encenicline hydrochloride

    CAS:
    <p>Encenicline hydrochloride (EVP-6124 hydrochloride) is a new-type partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs).</p>
    Formula:C16H17ClN2OS·HCl
    Purity:98.34% - 99.85%
    Color and Shape:Solid
    Molecular weight:357.3

    Ref: TM-T2285

  • (S)-UFR2709
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    (S)-UFR2709

    CAS:
    <p>(S)-UFR2709, a nAChR competitive antagonist, favors α4β2 over α7, reduces anxiety and alcohol use in rats.</p>
    Formula:C13H17NO2
    Color and Shape:Solid
    Molecular weight:219.284

    Ref: TM-T38903