AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 645 products of "AChR"
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Fmoc-Val-Ala-PAB-OH
CAS:Fmoc-Val-Ala-PAB-OH is a linker for ADCs and lysosomally cleavable RGD-paclitaxel conjugates.Formula:C30H33N3O5Purity:98.45% - 98.94%Color and Shape:SolidMolecular weight:515.6GNF-7
CAS:GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.Formula:C28H24F3N7O2Purity:97.05% - 99.7%Color and Shape:SolidMolecular weight:547.53Brompheniramine
CAS:Brompheniramine, an alkylamine antihistamine, targets H1 receptors (Kd=6.06nM) and has anticholinergic/depressant qualities. Blocks Ca/Na/hERG channels.Formula:C16H19BrN2Color and Shape:SolidMolecular weight:319.24Ilmetropium iodide
CAS:Ilmetropium iodide is a bronchodilator.Formula:C20H30INO3Purity:98.45%Color and Shape:SolidMolecular weight:459.36(-)-(S)-B-973B
CAS:(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.Formula:C24H26F2N6OPurity:99.52%Color and Shape:SolidMolecular weight:452.5Pirmenol
CAS:Pirmenol is a new antiarrhythmic drugFormula:C22H30N2OPurity:97.24%Color and Shape:SolidMolecular weight:338.49Glycopyrrolate
CAS:Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.Formula:C19H28BrNO3Purity:99.41% - 99.64%Color and Shape:SolidMolecular weight:398.33VU0357017 hydrochloride
CAS:VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.Formula:C18H28ClN3O3Purity:99% - 99.97%Color and Shape:SolidMolecular weight:369.89PNU-282987 S enantiomer free base
CAS:PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).Formula:C14H17ClN2OPurity:99.74%Color and Shape:SolidMolecular weight:264.75Ref: TM-T7695
1mg71.00€5mg161.00€10mg219.00€25mg338.00€50mg460.00€100mg623.00€200mg837.00€1mL*10mM (DMSO)180.00€Oxyphencyclimine
CAS:Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers.Formula:C20H28N2O3Color and Shape:SolidMolecular weight:344.45ZSET1446
CAS:ZSET1446 (ST-101) is a T-type calcium channel activator potentially for the treatment of learning deficits in various types of Alzheimer disease (AD) models.Formula:C15H12N2OPurity:99.32%Color and Shape:SolidMolecular weight:236.27Ref: TM-T8448
1mg50.00€5mg103.00€10mg144.00€25mg281.00€50mg409.00€100mg572.00€200mg772.00€1mL*10mM (DMSO)119.00€Piperidolate hydrochloride
CAS:Piperidolate hydrochloride, an antimuscarinic, reduces acetylcholine-induced intestinal spasms in rats and dogs.Formula:C21H26ClNO2Purity:99.5%Color and Shape:SolidMolecular weight:359.89Piperidolate
CAS:Piperidolate inhibits intestinal cramp induced by acetylcholineFormula:C21H25NO2Purity:98.45%Color and Shape:SolidMolecular weight:323.43Rivanicline hemioxalate
Rivanicline hemioxalate is a selective α4β2 nicotinic receptor agonist (K i =26 nM), over 1,000x preference to α7 (K i =3.6 μM), with limited side effects.Formula:C12H16N2O4Purity:98%Color and Shape:SolidMolecular weight:207.23Xanomeline tartrate
CAS:Xanomeline tartrate (LY 246708 tartrate) 是 M1和 M4 mAChR 激动剂，具有抗精神病样活性，可改善认知，可用于研究精神分裂症和阿尔茨海默病。Formula:C18H29N3O7SPurity:99.19% - 99.99%Color and Shape:SolidMolecular weight:431.5Pipecuronium bromide
CAS:Pipecuronium bromide (RGH-1106) is an nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker that causes muscle relaxation.Formula:C35H62Br2N4O4Purity:>99.99%Color and Shape:PowderMolecular weight:762.7AF-710B
CAS:AF710B is an enantiomer of AF710. AF-710B is also a sigma and M1 muscarinic receptors agonist.Formula:C20H27N3OSPurity:98.62% - 99.89%Color and Shape:SolidMolecular weight:357.51Monepantel
CAS:Monepantel (AAD1566) is an organic anthelmintic and an antagonist of nAChRs from roundworms and esophageostomy.Formula:C20H13F6N3O2SPurity:99.83%Color and Shape:White PowderMolecular weight:473.39Ref: TM-T16126
1mg93.00€5mg236.00€10mg340.00€25mg670.00€50mg964.00€100mg1,378.00€1mL*10mM (DMSO)259.00€Velufenacin
CAS:Velufenacin is an antagonist of muscarinic receptor[1].Formula:C19H20ClFN2O2Purity:99.65%Color and Shape:SolidMolecular weight:362.83Ref: TM-T9771
1mg47.00€5mg96.00€10mg156.00€25mg270.00€50mg370.00€100mg522.00€200mg687.00€1mL*10mM (DMSO)105.00€Pentoxyverine
CAS:Pentoxyverine (Carbetapentan) is an orally available cough suppressant, an antagonist of muscarinic receptor M1 and an agonist of the σ1 receptor.Formula:C20H31NO3Purity:97.11%Color and Shape:SolidMolecular weight:333.47
