AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 643 products of "AChR"
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Octamylamine
CAS:Octamylamine is a bioactive chemical.Formula:C13H29NColor and Shape:SolidMolecular weight:199.3761Lupanine hydrochloride
CAS:Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.Formula:C15H25ClN2OColor and Shape:SolidMolecular weight:284.83Dicloromezotiaz
CAS:Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.Formula:C19H12Cl3N3O2SColor and Shape:SolidMolecular weight:452.74Ebiratide TFA
Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.Formula:C48H73N11O10S·xC2HF3O2Color and Shape:SolidMolecular weight:996.23 (free base)Mant-GTPγS
CAS:Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.Formula:C18H23N6O14P3SColor and Shape:SolidMolecular weight:672.39PF-06827443
PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.Formula:C24H24N2O4Color and Shape:SolidMolecular weight:404.47Doxacurium Chloride
CAS:Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.Formula:C56H78ClN2O16Purity:98%Color and Shape:SolidMolecular weight:1070.69LtIA-F
LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.Formula:C86H121N25O22S4Color and Shape:SolidMolecular weight:1985.31α-Conotoxin PIA TFA
α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.Formula:C81H126F3N27O27S4Purity:98.81%Color and Shape:SolidMolecular weight:2095.3BTMPS
CAS:BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.Formula:C28H52N2O4Purity:98.1%Color and Shape:SolidMolecular weight:480.72Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Formula:C10H14N2OColor and Shape:SolidMolecular weight:178.23TC-2559 difumarate
CAS:TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.Formula:C20H26N2O9Color and Shape:SolidMolecular weight:438.43sabcomeline
CAS:Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.Formula:C10H15N3OColor and Shape:SolidMolecular weight:193.25VU6028418
CAS:VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).Formula:C23H27F3N4OColor and Shape:SolidMolecular weight:432.491Navafenterol saccharinate
CAS:AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).Formula:C45H47N7O9S3Color and Shape:SolidMolecular weight:926.09Angiopeptin TFA
CAS:Angiopeptin TFA: somatostatin analogue, sst2/sst5 partial agonist (IC50: 0.26/6.92 nM), suppresses GH & IGF-1, for atherosclerosis research.Formula:C58H73F6N11O14S2Color and Shape:SolidMolecular weight:1326.39Emraclidine
CAS:Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.Formula:C20H21F3N4OPurity:99.96%Color and Shape:SolidMolecular weight:390.4Ref: TM-T9694
1mg127.00€2mgTo inquire5mg305.00€10mg494.00€25mg882.00€50mg1,198.00€100mg1,586.00€1mL*10mM (DMSO)338.00€Biperiden Hydrochloride
CAS:Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.Formula:C21H30ClNOPurity:98%Color and Shape:SolidMolecular weight:347.92PDE4-IN-4
CAS:PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment ofFormula:C36H37Cl2N3O7SColor and Shape:SolidMolecular weight:726.67Irsogladine maleate
CAS:Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7Cl2N5Color and Shape:SolidMolecular weight:256.09
