AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 643 products of "AChR"
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3-hydroxy Darifenacin
CAS:3-hydroxy Darifenacin, darifenacin metabolite, blocks M1-5 muscarinic receptors with varying potency (Kis: 2.24-79.43 nM) in CHO cells.Formula:C28H30N2O3Color and Shape:SolidMolecular weight:442.559DSPE-PEG5000-RVG29
DSPE-PEG5000-RVG29 is a PEG compound comprised of DSPE and rabies virus glycoprotein 29 (RVG29). RVG29 specifically binds to nicotinic acetylcholine receptors (nAChR) at the blood-brain barrier (BBB) and facilitates passage through the BBB.Color and Shape:Odour SolidM4 mAChR agonist-1
CAS:M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).Formula:C14H18N4OSPurity:99.14%Color and Shape:SolidMolecular weight:290.38α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFormula:C83H125N27O27S5Purity:98%Color and Shape:SolidMolecular weight:2093.37Migrastatin
CAS:Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinicFormula:C27H39NO7Color and Shape:SolidMolecular weight:489.609Epiboxidine
CAS:Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.Formula:C10H14N2OColor and Shape:SolidMolecular weight:178.23Albanin A
Albanin A is a useful organic compound for research related to life sciences and the catalog number is T124310.Formula:C20H18O6Color and Shape:SolidMolecular weight:354.358R-(+)-Cotinine
CAS:R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.Formula:C10H12N2OColor and Shape:SolidMolecular weight:176.22bPiDDB
CAS:bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Formula:C24H38Br2N2Purity:98.72%Color and Shape:SolidMolecular weight:514.38Epiboxidine hydrochloride
CAS:Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.Formula:C10H15ClN2OColor and Shape:SolidMolecular weight:214.695-AMAM-2-CP
CAS:5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].Formula:C9H11ClN2OColor and Shape:SolidMolecular weight:198.65Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Formula:C10H12N2Color and Shape:SolidMolecular weight:160.22Hydroxybupropion
CAS:Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).Formula:C13H18ClNO2Purity:99.73%Color and Shape:Off-White SolidMolecular weight:255.74Ref: TM-T11588
1mg89.00€5mg204.00€10mg331.00€25mg545.00€50mg777.00€100mg1,063.00€1mL*10mM (DMSO)232.00€PDE4-IN-4
CAS:PDE4-IN-4 is a compound acting as both a potent M3 antagonist (p IC 50 = 10.2) and a PDE4 inhibitor (p IC 50 = 8.8), designed for inhalation-based treatment ofFormula:C36H37Cl2N3O7SColor and Shape:SolidMolecular weight:726.67PF-06827443
PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.Formula:C24H24N2O4Color and Shape:SolidMolecular weight:404.47nAChR agonist CMPI hydrochloride
CAS:CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.Formula:C18H20Cl2N4OColor and Shape:SolidMolecular weight:379.29MK-0969
CAS:MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C24H30F2N4O2Color and Shape:SolidMolecular weight:444.52Mant-GTPγS
CAS:Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.Formula:C18H23N6O14P3SColor and Shape:SolidMolecular weight:672.39Irsogladine maleate
CAS:Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C9H7Cl2N5Color and Shape:SolidMolecular weight:256.09M 8218
CAS:M 8218 is a bioactive chemical.Formula:C20H29NO2Color and Shape:SolidMolecular weight:315.45
