AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 574 products of "AChR"
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Biricodar dicitrate
CAS:<p>Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.</p>Formula:C46H57N3O21Purity:97.78% - 99.78%Color and Shape:SolidMolecular weight:987.95Sofiniclin
CAS:<p>Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).</p>Formula:C10H11Cl2N3Purity:98%Color and Shape:SolidMolecular weight:244.12Bibn 99
CAS:<p>Bibn 99, a lipophilic and selective muscarinic M2 receptor antagonist, has applications in cognitive performance and Alzheimer's Disease.</p>Formula:C31H42ClN5O3Color and Shape:SolidMolecular weight:568.15VU 6008667
CAS:VU 6008667 is a selective negative allosteric M5 NAM modulator (IC50s: 1.2 μM and 1.6 μM for human M5 and rat M5, respectively).Formula:C24H17ClF2N2O2Purity:98%Color and Shape:SolidMolecular weight:438.85Rivanicline
CAS:<p>Rivanicline is a selective α4β2 nicotinic receptor agonist (Ki=26 nM), with >1,000x less affinity for α7 receptors.</p>Formula:C10H14N2Purity:98%Color and Shape:SolidMolecular weight:162.23Rapacuronium bromide
CAS:<p>Rapacuronium bromide is an allosteric muscarinic acetylcholine receptor (mAChR) modulator.</p>Formula:C37H61BrN2O4Purity:98%Color and Shape:SolidMolecular weight:677.8ML375
CAS:<p>ML375 is a potent, selective and CNS penetrant M5 negative allosteric modulator (NAM).</p>Formula:C23H15ClF2N2O2Color and Shape:SolidMolecular weight:424.83CP-601927
CAS:<p>CP-601927 is a nicotinic acetylcholine receptor (NACHR) agonist with permeability, high affinity, and selectivity.</p>Formula:C12H12F3NColor and Shape:SolidMolecular weight:227.23Arecaidine propargyl ester tosylate
CAS:<p>Arecaidine propargyl ester tosylate is a muscarinic receptor agonist.</p>Formula:C17H21NO5SPurity:98%Color and Shape:SolidMolecular weight:351.42VMY-2-95
CAS:<p>VMY-2-95 is an α4β2 nicotinic acetylcholine receptors (nAChRs) selective desensitizer.</p>Formula:C17H16N2OColor and Shape:SolidMolecular weight:264.32RJR 2429 dihydrochloride
CAS:<p>nAChR agonist that displays selectivity for α4β2</p>Formula:C12H18Cl2N2Purity:98%Color and Shape:SolidMolecular weight:261.19J 104129 fumarate
CAS:<p>M3 muscarinic receptor antagonist</p>Formula:C24H36N2O2Purity:98%Color and Shape:SolidMolecular weight:384.55Alvameline maleate
CAS:<p>Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist.</p>Formula:C13H19N5O4Color and Shape:SolidMolecular weight:309.32Vinconate
CAS:<p>Vinconate is an indolonaphthyridine derivative and can stimulate the muscarinic acetylcholine receptor.</p>Formula:C18H20N2O2Purity:98%Color and Shape:SolidMolecular weight:296.36AT-1001
CAS:<p>AT-1001 is an α3β4 nAChR partial agonist reducing nicotine relapse and withdrawal with negligible impact on food response and dopamine release.</p>Formula:C15H21BrN2Color and Shape:SolidMolecular weight:309.24Rivanicline oxalate
CAS:<p>Rivanicline oxalate is an agonist of neuronal nicotinic receptor, showing high selectivity for the α4β2 subtype (Ki=26 nM).</p>Formula:C12H16N2O4Purity:98%Color and Shape:SolidMolecular weight:252.27Bradanicline HCl
CAS:<p>Bradanicline(TC-5619) is the agonist of Alpha-7 Nicotinic Receptor.</p>Formula:C22H24ClN3O2Color and Shape:SolidMolecular weight:397.9DREADD agonist 21 dihydrochloride
CAS:<p>DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].</p>Formula:C17H20Cl2N4Purity:98%Color and Shape:SolidMolecular weight:351.27BPIPP
CAS:<p>guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor</p>Formula:C22H16BrN3O3Purity:98%Color and Shape:SolidMolecular weight:450.28Procyclidine
CAS:<p>Procyclidine is an anticholinergic, muscarinic and NMDA antagonist used in Parkinson's and psychiatric disorder studies.</p>Formula:C19H29NOColor and Shape:SolidMolecular weight:287.44Oxybutynin R-isomer HCl
CAS:<p>Aroxybutynin, R-isomer of oxybutynin, is a muscarinic antagonist with antispasmodic effects on bladder muscle, weaker than atropine.</p>Formula:C22H32ClNO3Color and Shape:SolidMolecular weight:393.95VU0455691
CAS:<p>VU0455691 is a selective M1 Muscarinic Receptor Allosteric Modulators.</p>Formula:C24H25N5O3SPurity:98%Color and Shape:SolidMolecular weight:463.55Ambutonium bromide
CAS:<p>Ambutonium bromide is an antagonist of acetylcholine.</p>Formula:C20H27BrN2OPurity:98%Color and Shape:SolidMolecular weight:391.35(±)-Muscarine chloride
CAS:<p>(±)-Muscarine chloride is the racemate of Muscarine chloride. Muscarine is a prototypical agonist for the muscarinic acetylcholine receptor [1] [2].</p>Formula:C9H20ClNO2Color and Shape:SolidMolecular weight:209.71Methapyrilene
CAS:<p>Methapyrilene is a histamine H1 antagonist with sedative action.</p>Formula:C14H19N3SColor and Shape:Liquid Physical Description Clear Colorless Liquid (Ntp 1992)Molecular weight:261.39Milameline hydrochloride
CAS:<p>Milameline hydrochloride is a Muscarinic receptor agonist.</p>Formula:C8H15ClN2OPurity:98%Color and Shape:SolidMolecular weight:190.67Cycrimine
CAS:<p>Cycrimine: oral M1 mAChR blocker, lowers acetylcholine, antispasmodic, for Parkinson's and mental disorder studies.</p>Formula:C19H29NOColor and Shape:SolidMolecular weight:287.44Parapenzolate bromide
CAS:<p>Parapenzolate bromide is an orally active mAChR antagonist. parapenzolate bromide is an anticholinergic and antitussive agent.</p>Formula:C21H26BrNO3Color and Shape:SolidMolecular weight:420.347DPNB-ABT594
<p>DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates α4β2 over α7 nAChRs; used to study Ca²⁺ signaling in MHb.</p>Formula:C31H46ClN3O11Color and Shape:SolidMolecular weight:672.16AFDX384
CAS:<p>AFDX384 is potent M2/M4 selective antagonist.</p>Formula:C28H42N6O5SColor and Shape:SolidMolecular weight:574.74(S)-VQW-765
<p>(S)-VQW-765, oral α7 nAChR partial agonist, may improve cognition in Alzheimer's and schizophrenia.</p>Formula:C19H22N2OColor and Shape:SolidMolecular weight:294.39Mazaticol
CAS:<p>Mazaticol: an anticholinergic, blocks muscarinic receptors, inhibits dopamine uptake, used in Parkinson's research.</p>Formula:C21H27NO3S2Color and Shape:SolidMolecular weight:405.57J-104129 fumarate
CAS:<p>J-104129 fumarate is a potent M3 muscarinic receptor antagonist.</p>Formula:C28H40N2O6Color and Shape:SolidMolecular weight:500.63BMS-902483
CAS:<p>BMS-902483: potent α7 partial agonist; enhances rodent cognition; α7 EC50=9.3nM; 5-HT3A IC50=480nM.</p>Formula:C18H20N4OPurity:98%Color and Shape:SolidMolecular weight:308.38RLH 033
CAS:<p>RLH 033 is a selective ligand for the sigma 1 recognition site.</p>Formula:C25H31ClN2O4Purity:98%Color and Shape:SolidMolecular weight:458.98Talsaclidine
CAS:<p>Talsaclidine: full M1 agonist, partial M2/M3 agonist with neuron-stimulating effects.</p>Formula:C10H15NOPurity:98%Color and Shape:SolidMolecular weight:165.23A-85380 HCl
CAS:<p>A-85380 is an agonist of nicotinic acetylcholine receptor.</p>Formula:C9H14Cl2N2OColor and Shape:SolidMolecular weight:237.13Phenglutarimid
CAS:<p>Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.</p>Formula:C17H24N2O2Purity:98%Color and Shape:SolidMolecular weight:288.38Pirenzepine
CAS:<p>Pirenzepine targets M1 mAChR, curbs acid secretion, eases spasms, and has anti-cancer properties.</p>Formula:C19H21N5O2Color and Shape:SolidMolecular weight:351.4ENS-163 phosphate
CAS:<p>Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.</p>Formula:C11H19N2O5PSPurity:98%Color and Shape:SolidMolecular weight:322.32TMPH hydrochloride
CAS:<p>neuronal nicotinic ACh receptors (nAChRs) antagonist</p>Formula:C16H32ClNO2Purity:98%Color and Shape:SolidMolecular weight:305.889-CP-Ade Mesylate
CAS:<p>9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.</p>Formula:C11H17N5O3SPurity:99.81%Color and Shape:SolidMolecular weight:299.35Arecaidine but-2-ynyl ester tosylate
CAS:<p>mAChR M2 agonist</p>Formula:C18H23NO5SPurity:98%Color and Shape:SolidMolecular weight:365.44GSK575594A
CAS:<p>GSK575594A is a selective agonist of GPR55.</p>Formula:C24H23F2N3O3SColor and Shape:SolidMolecular weight:471.52(R)-Oxybutynin
CAS:<p>(R)-Oxybutynin: oral muscarinic blocker with antispasmodic effects, used in neurogenic bladder research.</p>Formula:C22H31NO3Color and Shape:SolidMolecular weight:357.49AC-42
CAS:<p>AC-42 is an allosteric agonist of M1 muscarinic receptor.</p>Formula:C20H31NOColor and Shape:SolidMolecular weight:301.47α7 nAchR-JAK2-STAT3 agonist 1
CAS:<p>α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM).</p>Formula:C25H30O6Color and Shape:SolidMolecular weight:426.5Ethybenztropine
CAS:<p>Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.</p>Formula:C22H27NOPurity:98%Color and Shape:SolidMolecular weight:321.46Anabasine hydrochloride
CAS:<p>neuronal nicotinic ACh receptor partial agonist</p>Formula:C10H15ClN2Purity:98%Color and Shape:White To Off-White SolidMolecular weight:198.693Flupyrimin
CAS:<p>Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].</p>Formula:C13H9ClF3N3OColor and Shape:SolidMolecular weight:315.68Adenylyl cyclase type 2 agonist-1
CAS:<p>Potent AC2 agonist with an EC50 of 90 nM, potential for respiratory disease treatment.</p>Formula:C27H17BrClNO5Color and Shape:SolidMolecular weight:550.78RJR-2403 oxalate
CAS:<p>RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.</p>Formula:C14H18N2O4Purity:98%Color and Shape:SolidMolecular weight:278.308Bibn 140
CAS:<p>Bibn 140 is a highly selective M2 antagonist, it is used to treat Alzheimer's disease and other cognitive disorders.</p>Formula:C32H44N4O3Purity:98%Color and Shape:SolidMolecular weight:532.72AZD 0328
CAS:<p>AZD 0328 is a nicotinic receptor agonist for α7 neurons.</p>Formula:C13H16N2OColor and Shape:SolidMolecular weight:216.28Nelonicline citrate
CAS:<p>Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.</p>Formula:C23H27N3O8SColor and Shape:SolidMolecular weight:505.54Bradanicline
CAS:<p>Bradanicline: potent α7 nAChR agonist, EC50=17 nM, Ki=1.4 nM, used in cognitive disorder research.</p>Formula:C22H23N3O2Color and Shape:SolidMolecular weight:361.44Asoxime dichloride
CAS:<p>Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.</p>Formula:C14H16Cl2N4O3Purity:99.86%Color and Shape:SolidMolecular weight:359.21Camylofine
CAS:<p>Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.</p>Formula:C19H32N2O2·2HClPurity:98%Color and Shape:SolidMolecular weight:393.4(Rac)-VU 6008667
CAS:<p>(Rac)-VU 6008667 is a selective M5 NAM with IC50 of 1.8 μM, high CNS penetration.</p>Formula:C24H17ClF2N2O2Purity:99.82%Color and Shape:SolidMolecular weight:438.85Pentolinium Tartrate
CAS:<p>Pentolinium Tartrate (Pendine) is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.</p>Formula:C15H32N2·2C4H5O6Purity:98%Color and Shape:SolidMolecular weight:538.6AF-DX 384 free base
CAS:<p>AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.</p>Formula:C27H38N6O2Purity:98%Color and Shape:SolidMolecular weight:478.63Pozanicline
CAS:<p>Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.</p>Formula:C11H16N2OPurity:98%Color and Shape:SolidMolecular weight:192.26CB-6673567
CAS:<p>CB-6673567 is a selective inhibitor of adenylyl cyclase.</p>Formula:C19H14N4O3Color and Shape:SolidMolecular weight:346.34NGX-267
CAS:<p>NGX-267, a muscarinic M1 agonist, is used potentially for the treatment of Xerostomia, Alzheimer's disease and cognitive.</p>Formula:C10H18N2OSColor and Shape:SolidMolecular weight:214.33Dac 5945
CAS:<p>DAC 5945 is a more effective muscarinic antagonist in the airways than in the heart.</p>Formula:C19H30ClN3OPurity:98%Color and Shape:SolidMolecular weight:351.91Hexocyclium metilsulfate
CAS:<p>Hexocyclium metilsulfate has anti-gastric secretory effects in humans.</p>Formula:C21H36N2O5SPurity:98%Color and Shape:SolidMolecular weight:428.59GS 283
CAS:<p>GS 283 is a Ca(2+) antagonist. GS 283 is also a weak histamine and muscarinic receptor blocker in rat and guinea pig tracheal smooth muscles.</p>Formula:C17H17NO3Color and Shape:SolidMolecular weight:283.32(R)-VU 6008667
CAS:<p>(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).</p>Formula:C24H17ClF2N2O2Color and Shape:SolidMolecular weight:438.85Anisodine hydrobromide
CAS:<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Formula:C17H22BrNO5Color and Shape:White Crystals Or Crystalline PowderMolecular weight:400.27Btm 1042
CAS:<p>Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.</p>Formula:C21H26ClN3OSColor and Shape:SolidMolecular weight:403.97Hyoscyamine hydrobromide
CAS:<p>Hyoscyamine hydrobromide is an agent of anticholinergic.</p>Formula:C17H24BrNO3Purity:98%Color and Shape:SolidMolecular weight:370.28Sazetidine A dihydrochloride
CAS:<p>α4β2 nicotinic acetylcholine receptor ligand</p>Formula:C15H21ClN2O2Purity:98%Color and Shape:SolidMolecular weight:296.79FR 121196
CAS:<p>FR 121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.</p>Formula:C12H16FN3O3SColor and Shape:SolidMolecular weight:301.34Prifuroline
CAS:<p>Prifuroline is an agent of antiarrhythmic.</p>Formula:C14H16N2OPurity:98%Color and Shape:SolidMolecular weight:228.29Epibatidine 2HCl
CAS:<p>Epibatidine 2HCl is a potent nicotinic agonist.</p>Formula:C11H15Cl3N2Purity:98%Color and Shape:SolidMolecular weight:281.61Flutropium Bromide
CAS:<p>Flutropium Bromide is a competitive antagonist of acetylcholine. It is used to treat asthma and chronic obstructive pulmonary.</p>Formula:C24H29BrFNO3Purity:98%Color and Shape:SolidMolecular weight:478.39Vesamicol
CAS:<p>Vesamicol is an experimental drug. It acting presynaptically by inhibiting acetylcholine uptake into synaptic vesicles and reducing its release.</p>Formula:C17H25NOPurity:98%Color and Shape:SolidMolecular weight:259.39Siltenzepine
CAS:<p>Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.</p>Formula:C19H20ClN3O4Purity:98%Color and Shape:SolidMolecular weight:389.83L 858051
CAS:<p>L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.</p>Formula:C29H48N2O7Color and Shape:SolidMolecular weight:536.7DBO-83
CAS:<p>DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.</p>Formula:C10H15Cl3N4Purity:98%Color and Shape:SolidMolecular weight:297.61ADX-10061
CAS:<p>ADX-10061 is a dopamine D1 receptor antagonist.</p>Formula:C19H20N2O4Color and Shape:SolidMolecular weight:340.37JN403
CAS:<p>JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.</p>Formula:C16H21FN2O2Color and Shape:SolidMolecular weight:292.35Tebanicline tosylate
CAS:<p>Tebanicline: synthetic, potent, non-opioid analgesic, less toxic than epibatidine; relieves neuropathic pain, acts on α3β4 and α4β2 nicotinic receptors.</p>Formula:C16H19ClN2O4SPurity:98%Color and Shape:SolidMolecular weight:370.85Terodiline hydrochloride
CAS:<p>Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),</p>Formula:C20H28ClNPurity:98%Color and Shape:SolidMolecular weight:317.9YM-46303
CAS:<p>YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in</p>Formula:C20H23ClN2O2Purity:>99.99%Color and Shape:SolidMolecular weight:358.86CHF5407
CAS:<p>CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on</p>Formula:C27H25BrF4N2O3SPurity:>99.99%Color and Shape:SolidMolecular weight:613.46YM-58790
CAS:<p>YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.</p>Formula:C27H31N3O2Purity:98.59%Color and Shape:SoildMolecular weight:429.55Metixene hydrochloride
CAS:<p>Metixene hydrochloride is an anticholinergic antiparkinsonian agent.</p>Formula:C20H24ClNSPurity:98%Color and Shape:SolidMolecular weight:345.93PQCA
CAS:<p>PQCA is a selective M1 receptor modulator with EC50s of 49 nM (monkey) and 135 nM (human), potential for Alzheimer's treatment.</p>Formula:C22H20N4O3Purity:99.88%Color and Shape:SolidMolecular weight:388.42Penehyclidine hydrochloride
CAS:<p>Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.</p>Formula:C20H30ClNO2Purity:99.79%Color and Shape:SolidMolecular weight:351.91PD-102807
CAS:<p>PD-102807 is a selective and competitive M4 muscarinic receptor antagonist for Parkinson's disease research, inhibit airway smooth muscle (ASM) contraction.</p>Formula:C23H24N2O4Purity:98.90%Color and Shape:SolidMolecular weight:392.45S 24795
CAS:<p>S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist.</p>Formula:C14H13BrINOPurity:99.934%Color and Shape:SolidMolecular weight:418.07S16961
CAS:<p>S16961 (S169611) is an agonist of nicotinic receptor.</p>Formula:C41H71NO6Purity:99.69%Color and Shape:SolidMolecular weight:674.01Afacifenacin
CAS:<p>Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.</p>Formula:C27H26F3N3O2Purity:99.83%Color and Shape:SolidMolecular weight:481.51UP202-56
CAS:<p>UP202-56 is an adenosinergic agonist and is an adenosine analog.</p>Formula:C33H37N7O4Purity:98%Color and Shape:SolidMolecular weight:595.69CB-7921220
CAS:<p>CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.</p>Formula:C14H12N2O2Purity:99.59%Color and Shape:SolidMolecular weight:240.26Cimetropium Bromide
CAS:<p>Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.</p>Formula:C21H28BrNO4Color and Shape:SolidMolecular weight:438.36GP531
CAS:<p>GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.</p>Formula:C16H21N5O4Color and Shape:SolidMolecular weight:347.37GAT107
CAS:<p>GAT107, a strong α7 nicotinic receptor modulator, aids inflammation and neuropathic pain in mice.</p>Formula:C18H17BrN2O2SPurity:99.33%Color and Shape:SolidMolecular weight:405.31SCH 57790
CAS:<p>SCH 57790: selective muscarinic M2 blocker, boosts acetylcholine & cognition, may treat Alzheimer's.</p>Formula:C25H31N3O2SPurity:99% - 99.12%Color and Shape:SolidMolecular weight:437.6TC-T 6000
CAS:<p>TC-T 6000 (hENT4-IN-1) is an ENT4 inhibitor with vasodilator activity that inhibits hENT1 and hENT2 for the study of cancer and cardiovascular damage.</p>Formula:C26H48N8O2Purity:98.14%Color and Shape:SolidMolecular weight:504.71Tarafenacin D-tartrate
CAS:<p>Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.</p>Formula:C25H26F4N2O8Purity:99.86%Color and Shape:SolidMolecular weight:558.48SIB-1553A hydrochloride
CAS:<p>SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand</p>Formula:C13H20ClNOSPurity:99.56% - 99.73%Color and Shape:SolidMolecular weight:273.82JNJ-39393406
CAS:<p>JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.</p>Formula:C19H18F2N6O3Purity:98.5%Color and Shape:SolidMolecular weight:416.38PHA 543613
CAS:<p>PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.</p>Formula:C15H17N3O2Purity:99.43% - 99.96%Color and Shape:SolidMolecular weight:271.31Thonzylamine hydrochloride
CAS:<p>Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.</p>Formula:C16H23ClN4OPurity:99.67%Color and Shape:White Crystalline PowderMolecular weight:322.83Desformylflustrabromine hydrochloride
CAS:<p>Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.</p>Formula:C17H12INO5Purity:98.12%Color and Shape:SolidMolecular weight:437.19AQW051
CAS:<p>AQW051 (VQW-765) is an oral α7-nAChR activator for cognitive impairments, used in anxiety disorder studies.</p>Formula:C19H22N2OPurity:99.94%Color and Shape:SolidMolecular weight:294.39PF-03635659
CAS:<p>PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.</p>Formula:C28H32N2O3Purity:98.39% - 99.83%Color and Shape:SolidMolecular weight:444.57rel-(1R,2R)-Vesamicol Hydrochloride
CAS:<p>Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.</p>Formula:C17H26ClNOPurity:99.88%Color and Shape:SolidMolecular weight:295.85SCH-900271
CAS:<p>SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.</p>Formula:C14H16N2O4Purity:98.82% - 99.93%Color and Shape:SolidMolecular weight:276.29CP-810123
CAS:<p>CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.</p>Formula:C14H18N4OPurity:98.63% - 99.60%Color and Shape:SolidMolecular weight:258.32McN-A 343
CAS:<p>McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.</p>Formula:C14H18Cl2N2O2Purity:99.65%Color and Shape:SolidMolecular weight:317.21Tribendimidine
CAS:<p>Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.</p>Formula:C28H32N6Purity:≥98%Color and Shape:SolidMolecular weight:452.59Xanomeline
CAS:<p>Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.</p>Formula:C14H23N3OSPurity:99.61%Color and Shape:SolidMolecular weight:281.42Dimethindene
CAS:<p>Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.</p>Formula:C20H24N2Purity:98.3% - 98.99%Color and Shape:SolidMolecular weight:292.42ASM-024
CAS:<p>ASM-024, a synthetic piperazine, activates nicotinic and β2-adrenergic receptors for potential asthma and bronchitis treatment with anti-inflammatory effects.</p>Formula:C15H25N2Purity:99.74%Color and Shape:SolidMolecular weight:233.37Otenzepad
CAS:<p>Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.</p>Formula:C24H31N5O2Purity:99.79%Color and Shape:SolidMolecular weight:421.54NB001
CAS:<p>NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.</p>Formula:C12H20N6OPurity:99.69%Color and Shape:Off-White To Pale Pink SolidMolecular weight:264.33Xanomeline oxalate
CAS:<p>Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.</p>Formula:C16H25N3O5SPurity:99.1%Color and Shape:SolidMolecular weight:371.45NKY80
CAS:<p>NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues.</p>Formula:C12H11N3O2Purity:99.88%Color and Shape:SolidMolecular weight:229.23Oxotremorine M iodide
CAS:<p>Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.</p>Formula:C11H19IN2OPurity:99.57%Color and Shape:SolidMolecular weight:322.19Iperoxo
CAS:<p>Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.</p>Formula:C10H17IN2O2Purity:99.81%Color and Shape:SolidMolecular weight:324.16Aceclidine
CAS:<p>Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular</p>Formula:C9H15NO2Purity:>99.99%Color and Shape:SolidMolecular weight:169.22Posatirelin
CAS:<p>Posatirelin, a synthetic peptide, modulates and nourishes brain systems, aiding in vascular dementia research.</p>Formula:C17H28N4O4Purity:98.08% - 98.87%Color and Shape:SolidMolecular weight:352.43GSK233705
CAS:<p>GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.</p>Formula:C24H29BrN2Purity:99.87% - 99.98%Color and Shape:SolidMolecular weight:425.4Temiverine hydrochloride
CAS:<p>Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.</p>Formula:C24H36ClNO3Purity:99.26% - 99.43%Color and Shape:SolidMolecular weight:422Zamifenacin fumarate
CAS:<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Formula:C31H33NO7Purity:99.88%Color and Shape:SolidMolecular weight:531.6LG 50643
CAS:<p>LG 50643 is a muscarinic antagonist.</p>Formula:C24H34INO2Purity:98%Color and Shape:SolidMolecular weight:495.44LY2033298
CAS:<p>LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.</p>Formula:C13H14ClN3O2SPurity:99.06%Color and Shape:SolidMolecular weight:311.79ICL-CCIC-0019
CAS:<p>ICL-CCIC-0019 inhibits ChoKα, causes G1 arrest, ER stress, and cancer cell apoptosis.</p>Formula:C26H44Br2N4Purity:99.54%Color and Shape:SolidMolecular weight:572.46PTAC oxalate
CAS:<p>muscarinic receptor ligand</p>Formula:C14H21N3O4S2Purity:98%Color and Shape:SolidMolecular weight:359.46N-Demethyl MK-6884
CAS:<p>N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.</p>Formula:C24H23N5OColor and Shape:SolidMolecular weight:397.47Adenylyl cyclase-IN-1
CAS:<p>Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].</p>Formula:C9H8N2S3Color and Shape:SolidMolecular weight:240.37Tiotropium Bromide hydrate
CAS:<p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>Formula:C19H24BrNO5S2Purity:98.44% - 99.41%Color and Shape:SolidMolecular weight:490.43Timepidium bromide
CAS:<p>Timepidium bromide is an agent of anticholinergic.</p>Formula:C17H22BrNOS2Purity:98%Color and Shape:SolidMolecular weight:400.4APS3
CAS:<p>APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].</p>Formula:C18H7Cl2F6N5O5S2Color and Shape:SolidMolecular weight:622.31VU0453595
CAS:<p>VU0453595 is a M1 positive allosteric modulator (PAM).</p>Formula:C18H15FN4OPurity:99.91%Color and Shape:SolidMolecular weight:322.34VU 0255035
CAS:<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Formula:C18H20N6O3S2Purity:98.09% - 98.1%Color and Shape:SolidMolecular weight:432.52ABT-418 hydrochloride
CAS:<p>ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.</p>Formula:C9H15ClN2OColor and Shape:SolidMolecular weight:202.68Muscarine tosylate
CAS:<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Formula:C16H27NO5SColor and Shape:SolidMolecular weight:345.45AR420626
CAS:<p>AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.</p>Formula:C21H18Cl2N2O3Purity:98.62%Color and Shape:SolidMolecular weight:417.29mAChR antagonist 1
CAS:<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Formula:C19H22N2O2Color and Shape:SolidMolecular weight:310.39Homatropine hydrochloride
CAS:<p>Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussive</p>Formula:C16H22ClNO3Color and Shape:SolidMolecular weight:311.83-Bromocytisine
CAS:<p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>Formula:C11H13BrN2OPurity:99.974%Color and Shape:SolidMolecular weight:269.14UFP-512
CAS:<p>UFP-512 is a selective delta-opioid (DOP) receptor agonist.</p>Formula:C31H33N5O5Purity:98%Color and Shape:SolidMolecular weight:555.62A-424274
CAS:<p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>Formula:C14H15N3Purity:98%Color and Shape:SolidMolecular weight:225.29L 687306
CAS:<p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>Formula:C11H15N3OColor and Shape:SolidMolecular weight:205.26BMS-933043
CAS:<p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>Formula:C16H19N7OPurity:98%Color and Shape:SolidMolecular weight:325.37Tematropium
CAS:<p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>Formula:C21H31NO8SPurity:99.89%Color and Shape:SolidMolecular weight:457.54(-)-Cevimeline hydrochloride hemihydrate
<p>(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.</p>Formula:C10H19ClNO1·5SPurity:98%Color and Shape:SolidMolecular weight:244.78Lu 26-046
CAS:<p>Lu 26-046 is a muscarinic receptor agonist.</p>Formula:C10H12N2OSColor and Shape:SolidMolecular weight:208.28(+)-Sparteine sulfate pentahydrate
<p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>Formula:C15H38N2O9SColor and Shape:SolidMolecular weight:422.54(+)-Cevimeline hydrochloride hemihydrate
<p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>Formula:C10H19ClNO1·5SPurity:98%Color and Shape:SolidMolecular weight:244.78Dihydro-β-erythroidine hydrobromide
CAS:<p>Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs).</p>Formula:C16H22BrNO3Purity:98%Color and Shape:White SolidMolecular weight:356.26WIN 62577
CAS:<p>WIN 62577 is a species-selective tachykinin NK1 receptor antagonist and also serves as an allosteric enhancer with micromolar potency at M3 receptors. Additionally, WIN 62577 demonstrates potent antiviral activity against SARS-CoV-2.</p>Formula:C29H31N3OColor and Shape:SolidMolecular weight:437.576Metoquizine
CAS:<p>Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.</p>Formula:C22H27N5OPurity:98%Color and Shape:SolidMolecular weight:377.48(S)-Albuterol
CAS:<p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>Formula:C13H21NO3Color and Shape:SolidMolecular weight:239.311nAChR antagonist 1
CAS:<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Formula:C19H22N4O2Color and Shape:SolidMolecular weight:338.41,9-Dideoxyforskolin
CAS:<p>The compound is an inactive analog of forskolin(an adenylyl cyclase activator).</p>Formula:C22H34O5Purity:98%Color and Shape:SolidMolecular weight:378.5LY593093
CAS:<p>LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.</p>Formula:C32H30FN3O2Purity:98%Color and Shape:SolidMolecular weight:507.6CHF-6366
CAS:<p>CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.</p>Formula:C42H48N6O8Color and Shape:SolidMolecular weight:764.87VU6007496
CAS:<p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>Formula:C25H27N5O2Color and Shape:SolidMolecular weight:429.51UB 165
CAS:<p>Subtype-selective nicotinic agonist</p>Formula:C13H15ClN2Purity:98%Color and Shape:SolidMolecular weight:234.72VU6016235
CAS:<p>VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.</p>Formula:C21H22N4OSColor and Shape:SolidMolecular weight:378.49TDI-11861
CAS:<p>TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.</p>Formula:C22H25ClF2N6O3Color and Shape:SolidMolecular weight:494.92Dihydro-β-erythroidine
CAS:<p>Dihydro-β-erythroidine, a competitive nicotinic receptor antagonist, effectively blocks the discriminative stimulus properties and inhibits the anxiolytic</p>Formula:C16H21NO3Color and Shape:SolidMolecular weight:275.34TAAR1 agonist 2
CAS:<p>TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), also displays agonistic properties at H1 receptors and activates various muscarinic acetylcholine receptors, including the M2 receptor (pEC50=5). This compound is utilized in researching neuropsychiatric diseases.</p>Formula:C9H11NOColor and Shape:SolidMolecular weight:149.19VU6005806
CAS:<p>VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.</p>Formula:C17H16F3N7O2SPurity:98%Color and Shape:SolidMolecular weight:439.41AChE/BChE-IN-10
CAS:<p>AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.</p>Formula:C26H30N2O2Purity:99.55% - 99.88%Color and Shape:SoildMolecular weight:402.53MG 624
CAS:<p>neuronal α7 nAChR antagonist</p>Formula:C22H30INOColor and Shape:SolidMolecular weight:451.38VU6000918
CAS:<p>VU6000918 is a positive allosteric modulator that targets the muscarinic acetylcholine receptor subtype M4. It exhibits a half maximal effective concentration (EC50) of 19 nM for the human M4 receptor.</p>Formula:C18H17F2N5OSColor and Shape:SolidMolecular weight:389.42Lupinine
CAS:<p>Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.</p>Formula:C10H19NOPurity:99.95%Color and Shape:SolidMolecular weight:169.26Oxitropium Bromide
CAS:<p>Oxitropium bromide, a mAChR blocker, treats asthma and COPD as an anticholinergic bronchodilator.</p>Formula:C19H26BrNO4Purity:98%Color and Shape:SolidMolecular weight:412.32
