AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 620 products of "AChR"
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(S)-Albuterol
CAS:<p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>Formula:C13H21NO3Color and Shape:SolidMolecular weight:239.311TDI-11861
CAS:TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.Formula:C22H25ClF2N6O3Color and Shape:SolidMolecular weight:494.92Acetylethylcholine mustard hydrochloride
CAS:Acetylethylcholine mustard hydrochloride is a choline acetyl-transferase inhibitor that decreases muscle contraction frequency by inhibiting the synthesis of acetyl-beta-methylcholine (Ach), with a half-maximal inhibitory concentration (IC50) of 1.22 mM. It serves as an irreversible ligand for the high-affinity choline transport system and functions as a specific presynaptic long-acting cholinergic toxin. Additionally, acetylethylcholine mustard hydrochloride is a precursor to the ethylcholine mustard aziridinium ion.Formula:C8H17Cl2NO2Molecular weight:230.132Dihydro-β-erythroidine hydrobromide
CAS:Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs).Formula:C16H22BrNO3Purity:98%Color and Shape:White SolidMolecular weight:356.26LY593093
CAS:LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.Formula:C32H30FN3O2Purity:98%Color and Shape:SolidMolecular weight:507.61,9-Dideoxyforskolin
CAS:The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Formula:C22H34O5Purity:98%Color and Shape:SolidMolecular weight:378.5VU6005806
CAS:VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.Formula:C17H16F3N7O2SPurity:98%Color and Shape:SolidMolecular weight:439.41(+)-Cevimeline hydrochloride hemihydrate
(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.Formula:C10H19ClNO1·5SPurity:98%Color and Shape:SolidMolecular weight:244.78UB 165
CAS:Subtype-selective nicotinic agonistFormula:C13H15ClN2Purity:98%Color and Shape:SolidMolecular weight:234.72(+)-Sparteine sulfate pentahydrate
(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.Formula:C15H38N2O9SColor and Shape:SolidMolecular weight:422.54WIN 62577
CAS:WIN 62577 is a species-selective tachykinin NK1 receptor antagonist and also serves as an allosteric enhancer with micromolar potency at M3 receptors. Additionally, WIN 62577 demonstrates potent antiviral activity against SARS-CoV-2.Formula:C29H31N3OColor and Shape:SolidMolecular weight:437.576Metoquizine
CAS:Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.Formula:C22H27N5OPurity:98%Color and Shape:SolidMolecular weight:377.48(-)-Cevimeline hydrochloride hemihydrate
(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.Formula:C10H19ClNO1·5SPurity:98%Color and Shape:SolidMolecular weight:244.78nAChR antagonist 1
CAS:Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.Formula:C19H22N4O2Color and Shape:SolidMolecular weight:338.4Dihydro-β-erythroidine
CAS:Dihydro-β-erythroidine, a competitive nicotinic receptor antagonist, effectively blocks the discriminative stimulus properties and inhibits the anxiolyticFormula:C16H21NO3Color and Shape:SolidMolecular weight:275.34AChE/BChE-IN-10
CAS:<p>AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.</p>Formula:C26H30N2O2Purity:99.55% - 99.88%Color and Shape:SoildMolecular weight:402.53VU6000918
CAS:VU6000918 is a positive allosteric modulator that targets the muscarinic acetylcholine receptor subtype M4. It exhibits a half maximal effective concentration (EC50) of 19 nM for the human M4 receptor.Formula:C18H17F2N5OSColor and Shape:SolidMolecular weight:389.42Lupinine
CAS:<p>Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.</p>Formula:C10H19NOPurity:99.95%Color and Shape:SolidMolecular weight:169.26Oxitropium Bromide
CAS:Oxitropium bromide, a mAChR blocker, treats asthma and COPD as an anticholinergic bronchodilator.Formula:C19H26BrNO4Purity:98%Color and Shape:SolidMolecular weight:412.32
