AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Found 643 products of "AChR"
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TMPH
CAS:TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.Formula:C16H31NO2Purity:99.78%Color and Shape:SoildMolecular weight:269.42Ref: TM-T60080
2mg35.00€5mg55.00€10mg84.00€25mg133.00€50mg205.00€100mg301.00€200mg425.00€1mL*10mM (DMSO)54.00€Metixene hydrochloride hydrate
CAS:Metixene HCl hydrate is a potential anticholinergic for Parkinson's with IC50 of 55 nM and Ki of 15 nM against muscarine receptors.Formula:C20H26ClNOSPurity:99.99%Color and Shape:SolidMolecular weight:363.95Telenzepine dihydrochloride
CAS:muscarinic M1 receptor antagonistFormula:C19H23ClN4O2SPurity:98%Color and Shape:SolidMolecular weight:406.93Solifenacin D5 hydrochloride
CAS:Solifenacin D5 HCl: deuterium-labeled M1, M2, M3 muscarinic receptor antagonist with pKi 7.6, 6.9, 8.0.Formula:C23H27ClN2O2Purity:98%Color and Shape:SolidMolecular weight:403.96Fipexide hydrochloride
CAS:Fipexide (hydrochloride) is a kind of psychoactive drug of the piperazine class.Formula:C20H22Cl2N2O4Color and Shape:SolidMolecular weight:425.31N6-Methyladenosine 5'-monophosphate disodium salt
CAS:N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator and an inhibitor of adenylate kinase II.Formula:C11H14N5Na2O7PPurity:99.36% - 99.36%Color and Shape:SolidMolecular weight:405.21Fesoterodine L-mandelate
CAS:Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB).Formula:C34H45NO6Color and Shape:SolidMolecular weight:563.735YM-58790 hydrochloride
CAS:YM-58790 is a potent M3 muscarinic receptor antagonist(Ki of 15 nM).Formula:C27H32ClN3O2Purity:98%Color and Shape:SolidMolecular weight:466.02Palmatine hydroxide
CAS:Palmatine hydroxide: oral IDO-1 inhibitor (IC50: 3-157μM), targets WNV protease, has anti-cancer/viral and neuroprotective properties.Formula:C21H23NO5Color and Shape:SolidMolecular weight:369.41Biperiden
CAS:Biperiden is a muscarinic antagonist for Parkinson's and drug-induced extrapyramidal symptoms.Formula:C21H29NOPurity:99.65%Color and Shape:Crystals SolidMolecular weight:311.46Ispronicline
CAS:Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitiveFormula:C14H22N2OPurity:97.70% - 99.16%Color and Shape:SolidMolecular weight:234.34NBTGR
CAS:NBTGR is a potent nucleoside transport inhibitor(adenosine uptake ,Ki of 70 nM).Formula:C17H18N6O6SPurity:98%Color and Shape:SolidMolecular weight:434.43β2AR/M-receptor agonist-2
CAS:β2AR/M-receptor agonist-2 is a dual-function compound acting as a muscarinic antagonist and β2 adrenoceptor agonist (MABA).Formula:C36H49ClN4O7SColor and Shape:SolidMolecular weight:717.31(S)-(+)-Dimethindene maleate
CAS:(S)-(+)-Dimethindene maleate is an orally available, selective muscarinic M2 receptor and histamine H1 receptor antagonist that inhibits muscarinic M1 receptorsFormula:C24H28N2O4Purity:99.94%Color and Shape:SolidMolecular weight:408.49Dexetimide
CAS:Dexetimide, a muscarinic receptor antagonist, treats neuroleptic-induced parkinsonism.Formula:C23H26N2O2Color and Shape:SolidMolecular weight:362.46Varenicline Hydrochloride
CAS:Varenicline Hydrochloride (CP 526555) is an orally active partial agonist of the α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM).Formula:C13H14ClN3Purity:99.854%Color and Shape:SolidMolecular weight:247.72Ref: TM-T23502
1mg37.00€5mg77.00€10mg99.00€25mg182.00€50mg282.00€100mg419.00€200mg612.00€1mL*10mM (DMSO)83.00€SSR180711 hydrochloride
CAS:SSR180711 hydrochloride (SSR-180711A HCl) is an Alpha7 nicotinic acetylcholine partial agonist that can be used to study neurolysis.Formula:C14H18BrClN2O2Purity:99.22%Color and Shape:SolidMolecular weight:361.66Glycerophosphoinositol choline
CAS:Glycerophosphoinositol choline is the salt of choline and glycerophosphoinositol.Formula:C14H32NO12PColor and Shape:SolidMolecular weight:437.38Cevimeline hydrochloride
CAS:Cevimeline HCl is a muscarinic agonist enhancing salivary and sweat gland secretion.Formula:C10H18ClOSColor and Shape:SolidMolecular weight:235.77Tolterodine
CAS:Tolterodine ((R)-(+)-Tolterodine) is an mACh antagonist used in the treatment of detrusor instability and overactive bladder syndrome.Formula:C22H31NOPurity:99.71%Color and Shape:White Like Or Light Brown Crystalline PowderMolecular weight:325.49(±)-Darifenacin
CAS:(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.Formula:C28H30N2O2Color and Shape:SolidMolecular weight:426.55NSC 23766
CAS:NSC 23766 is a Rac1 GTPase inhibitor by targeting GEFs, inhibiting cell proliferation.NSC23766 competitively inhibits M2 mAChR-induced Rac1 activation.Formula:C24H35N7Purity:99.49%Color and Shape:SolidMolecular weight:421.58ABT-107
CAS:ABT-107: α7 neuronal receptor agonist; protects rats' brains from 6-OHDA-induced damage.Formula:C19H20N4OColor and Shape:SolidMolecular weight:320.396VU0467485
CAS:VU0467485 boosts ACh at M4 receptors (EC50: 26.6 nM rat, 78.8 nM human), selective for M4 over M1/2/3/5.Formula:C17H17FN4O2SPurity:98%Color and Shape:SolidMolecular weight:360.41Clorprenaline
CAS:Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.Formula:C11H16ClNOPurity:98.9%Color and Shape:SolidMolecular weight:213.7NKH477
CAS:NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.Formula:C27H44ClNO8Purity:98% - 98%Color and Shape:SolidMolecular weight:546.09Cevimeline
CAS:Cevimeline: muscarinic agonist, treats dry mouth & Sjögren's, boosts saliva post-cancer radiotherapy.Formula:C10H17NOSColor and Shape:Off-White SolidMolecular weight:199.31Dibucaine hydrochloride
CAS:Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.Formula:C20H30ClN3O2Purity:99.66%Color and Shape:White PowderMolecular weight:379.92Tebanicline dihydrochloride
CAS:Tebanicline dihydrochloride: oral analgesic, nAChR modulator, Ki=37 pM at α4β2 receptors, inhibits cytisine binding.Formula:C9H13Cl3N2OColor and Shape:SolidMolecular weight:271.57NS3861 fumarate
CAS:NS3861 fumarate, a partial α3β4 nAChR agonist, binds α3β2, α4β4, α4β2 with Ki values of 0.62, 25, 7.8, 55 nM.Formula:C16H18BrNO4SColor and Shape:SolidMolecular weight:400.29Sabcomeline hydrochloride
CAS:Sabcomeline is a selective M1 receptor partial agonist.Formula:C10H16ClN3OColor and Shape:SolidMolecular weight:229.71DL-Cystine
CAS:DL-Cystine is a cysteine derivative that inhibits endothelial cell proliferation by regulating TGFβ1. a GPR inhibitor and nAChR agonist .Formula:C6H12N2O4S2Color and Shape:SolidMolecular weight:240.3Pirmenol hydrochloride
CAS:Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μMFormula:C22H31ClN2OColor and Shape:SolidMolecular weight:374.95Harman hydrochloride
CAS:Harman hydrochloride triggers CYP1A1 gene via AhR, potentially causing mutations and cancer.Formula:C12H11ClN2Purity:99.35%Color and Shape:SolidMolecular weight:218.68Tebanicline hydrochloride
CAS:Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.Formula:C9H12Cl2N2OPurity:91.74% - 98.78%Color and Shape:SolidMolecular weight:235.11BNC210
CAS:BNC210 (IW-2143) is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.Formula:C17H23N3O3Purity:97.05% - >99.99%Color and Shape:SolidMolecular weight:317.38VU0119498
CAS:VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.Formula:C15H10BrNO2Purity:97.56%Color and Shape:SolidMolecular weight:316.15VU0152100
CAS:VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).Formula:C18H19N3O2SPurity:99.56%Color and Shape:SolidMolecular weight:341.43Ref: TM-T17238
2mg39.00€5mg58.00€10mg92.00€25mg195.00€50mg325.00€100mg522.00€200mg743.00€1mL*10mM (DMSO)64.00€Nitrobenzylthioinosine
CAS:Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.
Formula:C17H17N5O6SPurity:99.69% - 99.74%Color and Shape:Off-White SolidMolecular weight:419.41Batefenterol Succinate
CAS:Batefenterol Succinate is a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.Formula:C44H48ClN5O11Color and Shape:SolidMolecular weight:858.34VU0467154
CAS:VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.Formula:C17H15F3N4O3S2Purity:99.51% - 99.53%Color and Shape:SolidMolecular weight:444.45Ref: TM-T17244
1mg47.00€2mg63.00€5mg92.00€10mg126.00€25mg236.00€50mg400.00€100mg695.00€200mg945.00€1mL*10mM (DMSO)101.00€NS9283
CAS:NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.
Formula:C14H8N4OPurity:99.12%Color and Shape:SolidMolecular weight:248.24ML380
CAS:ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).Formula:C23H25F3N4O3SPurity:99.69%Color and Shape:SolidMolecular weight:494.53Ref: TM-T28069
2mg47.00€5mg71.00€10mg113.00€25mg178.00€50mg334.00€100mg500.00€500mg1,099.00€1mL*10mM (DMSO)78.00€VU0238441
CAS:VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.Formula:C16H9ClF3NO2Purity:100%Color and Shape:SolidMolecular weight:339.7Isopropamide Iodide
CAS:Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.
Formula:C23H33IN2OPurity:99.67%Color and Shape:SolidMolecular weight:480.43Mc-Val-Ala-PAB
CAS:Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).Formula:C25H34N4O6Purity:98.34% - 99.24%Color and Shape:SolidMolecular weight:486.56Nitenpyram
CAS:Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.Formula:C11H15ClN4O2Purity:99.03%Color and Shape:Light-Yellow CrystalMolecular weight:270.72Mecamylamine hydrochloride
CAS:Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.Formula:C11H22ClNPurity:99.76% - >99.99%Color and Shape:White SolidMolecular weight:203.75Adiphenine
CAS:Adiphenine is an inhibitor of nicotinic receptors.Formula:C20H25NO2Color and Shape:SolidMolecular weight:311.42Solifenacin hydrochloride
CAS:Solifenacin Hcl is a muscarinic receptor antagonist.Formula:C23H27ClN2O2Purity:98%Color and Shape:SolidMolecular weight:398.93
