Serine Protease
Serine protease inhibitors are compounds that target and inhibit serine proteases, a group of enzymes characterized by a serine residue at their active site. These proteases are involved in numerous physiological processes, including digestion, immune response, blood coagulation, and inflammation. Serine protease inhibitors are important for studying diseases where these enzymes are dysregulated, such as cardiovascular diseases, cancer, and inflammatory conditions. At CymitQuimica, we provide serine protease inhibitors to support your research in enzymology, disease mechanisms, and therapeutic interventions.
Found 50 products of "Serine Protease"
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TAO Kinase inhibitor 2
CAS:<p>TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.</p>Formula:C25H24N2O3Purity:98.58%Color and Shape:SoildMolecular weight:400.47BAY-85-8501
CAS:<p>BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)</p>Formula:C22H17F3N4O3SPurity:99.16%Color and Shape:SolidMolecular weight:474.46PMSF
CAS:<p>PMSF (Phenylmethylsulfonyl fluoride) is an irreversible inhibitor of serine/cysteine protease , preparation of cell lysates. High-Quality, Low-Cost!</p>Formula:C7H7FO2SPurity:97.75% - 99.88%Color and Shape:White To Cream SolidMolecular weight:174.19Tilpisertib fosmecarbil TFA
CAS:<p>Tilpisertib fosmecarbil TFA, the TFA salt form of Tilpisertib, acts as an inhibitor of serine/threonine kinases. This compound also exhibits anti-inflammatory activity.</p>Formula:C37H37ClF3N8O9PColor and Shape:SolidMolecular weight:861.16Ala-Phe-Pro-pNA TFA
<p>Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.</p>Color and Shape:Odour SolidBCX 1470 hydrochloride
<p>BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.</p>Formula:C14H11ClN2O2S2Purity:99.71%Color and Shape:SoildMolecular weight:338.83Protease Inhibitor Library
<p>A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;</p>Color and Shape:Odour SolidKKI-5
CAS:<p>KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.</p>Formula:C35H55N11O9Purity:98%Color and Shape:SolidMolecular weight:773.88AE-3763
CAS:<p>AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).</p>Formula:C23H34F3N5O7Purity:98%Color and Shape:SolidMolecular weight:549.54Patamostat HCl
CAS:<p>Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50</p>Formula:C20H21ClN4O4SPurity:99.15% - 99.76%Color and Shape:SoildMolecular weight:448.92MeOSuc-AAPA-CMK
<p>MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].</p>Formula:C20H31ClN4O8Color and Shape:SolidMolecular weight:490.94α 1 Antichymotrypsin, Human Plasma
CAS:<p>Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.</p>Color and Shape:SolidRoseltide rT1
CAS:<p>Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 μM) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8). It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.</p>Formula:C110H177N31O31S6Color and Shape:SolidMolecular weight:2622.16Lonodelestat TFA
<p>Lonodelestat TFA, an oral peptide, selectively inhibits hNE, potentially aiding in CF research.</p>Formula:C73H112F3N15O21Color and Shape:SolidMolecular weight:1592.75Tiprelestat
CAS:<p>Tiprelestat: strong inhibitor of human neutrophil elastase, anti-inflammatory, antimicrobial, used in inflammation/immune research.</p>Formula:C254H416N72O75S10Color and Shape:SolidMolecular weight:5999.09α-Methyl-DL-aspartic acid
CAS:<p>α-Methyl-DL-aspartic acid specifically inhibits argininosuccinate synthase (ASS), the rate-limiting enzyme in 1-citrulline-to-1-arginine recycling.</p>Formula:C5H9NO4Purity:99.91%Color and Shape:SolidMolecular weight:147.13Recombinant Trypsin
<p>Recombinant Trypsin is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine.</p>Dansyl-Glu-Gly-Arg-Chloromethylketone
CAS:<p>Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activated</p>Formula:C26H36ClN7O7SColor and Shape:SolidMolecular weight:626.12Suc-AAP-Abu-pNA
CAS:<p>Suc-AAP-Abu-pNA is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,</p>Formula:C25H34N6O9Color and Shape:SolidMolecular weight:562.57SFTI-1
CAS:<p>SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.</p>Formula:C67H104N18O18S2Color and Shape:SolidMolecular weight:1513.78Chymotrypsinogen
CAS:<p>Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .</p>Color and Shape:SolidPKR-IN-C51
CAS:<p>PKR-IN-C51 is ATP-competitive protein kinase R (PKR) inhibitor that inhibits intracellular PKR activation and autophosphorylation. Ser/Thr kinase.</p>Formula:C23H21N5Purity:98.94%Color and Shape:SolidMolecular weight:367.45Urokinase
CAS:<p>Urokinase (uPA) is a serine protease that activates plasminogen to plasmin, crucial for thrombolysis and ECM degradation.</p>Color and Shape:SolidGSK-690693
CAS:<p>GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.</p>Formula:C21H27N7O3Purity:98.07% - 99.77%Color and Shape:SolidMolecular weight:425.482-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one
CAS:<p>2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.</p>Formula:C14H7BrClNO2Purity:97.36%Color and Shape:SolidMolecular weight:336.57Cetraxate hydrochloride
CAS:<p>Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.</p>Formula:C17H24ClNO4Purity:99.75%Color and Shape:SolidMolecular weight:341.83WNK463
CAS:<p>WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).</p>Formula:C21H24F3N7O2Purity:>99.99% - ≥95%Color and Shape:SolidMolecular weight:463.46WNK-IN-11
CAS:<p>WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)</p>Formula:C21H21Cl2N5OSPurity:98.32%Color and Shape:SolidMolecular weight:462.4Alvelestat
CAS:<p>Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.</p>Formula:C25H22F3N5O4SPurity:98% - >99.99%Color and Shape:SolidMolecular weight:545.53ML281
CAS:<p>ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.</p>Formula:C22H19N3O2SPurity:99.12% - 99.87%Color and Shape:SolidMolecular weight:389.472,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
CAS:<p>2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine</p>Formula:C13H16O3Purity:99.53% - 99.81%Color and Shape:SolidMolecular weight:220.26Ceritinib
CAS:<p>Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.</p>Formula:C28H36ClN5O3SPurity:98.52% - 99.77%Color and Shape:SolidMolecular weight:558.14Lanadelumab
CAS:<p>Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.</p>Purity:95% - 95%Color and Shape:LiquidGalegenimab
CAS:<p>Galegenimab (FHTR 2163; RG 6147; RO 7171009) is an HTRA1 antibody fragment for AMD research.</p>Purity:95% - 95%Color and Shape:LiquidMEGA-9
CAS:<p>MEGA-9 (Nonanoyl-N-Methylglucamide) solubilizes membrane protein and can be used as a nonionic detergent.</p>Formula:C16H33NO6Purity:99.9%Color and Shape:SolidMolecular weight:335.44BMS-363131
CAS:<p>BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.</p>Formula:C28H40N6O5Purity:97.99%Color and Shape:SolidMolecular weight:540.65p-Aminobenzamidine dihydrochloride
CAS:<p>4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type</p>Formula:C7H11Cl2N3Purity:99.00% - 99.56%Color and Shape:SolidMolecular weight:208.088ZD8321
CAS:<p>ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).</p>Formula:C18H28F3N3O5Purity:98%Color and Shape:SolidMolecular weight:423.43ZD-0892
CAS:<p>ZD-0892: potent, selective neutrophil elastase inhibitor; Ki 6.7 nM (human), 200 nM (porcine).</p>Formula:C24H32F3N3O5Purity:95% - 99.53%Color and Shape:SolidMolecular weight:499.52APC 366
CAS:<p>APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).</p>Formula:C22H28N6O4Purity:99.8%Color and Shape:SolidMolecular weight:440.5ZM223 hydrochloride (2031177-48-5 free base)
<p>ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.</p>Formula:C23H18ClF3N4O2S2Purity:98%Color and Shape:SolidMolecular weight:538.99AGLME
CAS:<p>AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.</p>Formula:C11H21N3O4Color and Shape:SolidMolecular weight:259.3WNK1-IN-1
CAS:<p>WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.</p>Formula:C13H15BrCl2N2O4SPurity:98.09%Color and Shape:SolidMolecular weight:446.14IPR-803
CAS:<p>IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.</p>Formula:C27H23N3O4Purity:95%Color and Shape:SolidMolecular weight:453.49FK706
CAS:<p>FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.</p>Formula:C26H33F3N4NaO7Color and Shape:SolidMolecular weight:593.556LM-030
CAS:<p>LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).</p>Formula:C46H72N8O12Color and Shape:SolidMolecular weight:929.11Feniralstat
CAS:<p>Feniralstat (KVD-824) is a selective and potent kallikrein (kallikrein) inhibitor, useful in immune system diseases and cardiovascular disease research.</p>Formula:C26H25F2N5O4Purity:99.52%Color and Shape:SolidMolecular weight:509.51Matriptase-IN-2 free base
CAS:<p>Matriptase-IN-2 free base, a matriptase inhibitor with a K i of 5 nM, has potential applications in musculoskeletal system disorder research (WO2011023958A1; compound 432) [1].</p>Formula:C29H33Cl2N5O3SColor and Shape:SolidMolecular weight:602.58TMPRSS6-IN-1 TFA
<p>TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease). TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and β-thalassemia in mice.</p>Formula:C35H41F3N8O6S2Color and Shape:SolidMolecular weight:790.875MeO-Suc-Ala-Ala-Pro-Ala-CMK
CAS:<p>MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE) with an IC50 of 20.3 μM. It effectively inhibits the hydrolysis of substrates like lung tissue elastin by HNE and is applicable in studies related to conditions such as chronic obstructive pulmonary disease (COPD).</p>Formula:C20H31ClN4O7Color and Shape:SolidMolecular weight:474.936
