Serine Protease
Serine protease inhibitors are compounds that target and inhibit serine proteases, a group of enzymes characterized by a serine residue at their active site. These proteases are involved in numerous physiological processes, including digestion, immune response, blood coagulation, and inflammation. Serine protease inhibitors are important for studying diseases where these enzymes are dysregulated, such as cardiovascular diseases, cancer, and inflammatory conditions. At CymitQuimica, we provide serine protease inhibitors to support your research in enzymology, disease mechanisms, and therapeutic interventions.
Found 56 products for "Serine Protease".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BAY-85-8501
CAS:BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)Formula:C22H17F3N4O3SPurity:99.16%Color and Shape:SolidMolecular weight:474.46Ref: TM-T12613L
1mg92.00€2mg122.00€5mg200.00€1mL*10mM (DMSO)208.00€10mg298.00€25mg535.00€50mg750.00€100mg1,035.00€TAO Kinase inhibitor 2
CAS:TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.Formula:C25H24N2O3Purity:98.58%Color and Shape:SolidMolecular weight:400.47Kallikrein 5-IN-2 TFA
Kallikrein5-IN-2 TFA is the trifluoroacetate salt form of Kallikrein5-IN-2. It acts as a selective inhibitor of kallikrein5 (KLK5), with a pIC50 value of 7.1. Kallikrein5-IN-2 TFA exhibits no phototoxicity at 100 μg/mL and is non-irritating. The compound remains stable in non-oxidative conditions within a pH range of 4 to 8. Kallikrein5-IN-2 shows potential for improving Netherton syndrome.Formula:C25H23F3N6O3Color and Shape:SolidMolecular weight:512.17837hCAXII-IN-10
hCAXII-IN-10 (Compound 18b) acts as a dual inhibitor of human carbonic anhydrase isoenzyme XII (hCAXII) and cathepsin B, with a Ki value of 2.2 nM. It inhibits the function of hCAXII in creating a pH microenvironment conducive to tumor growth, showing promise for use in cancer research.Color and Shape:Odour SolidZ-APF-CMK
CAS:Z-APF-CMK is a selective inhibitor of the calcium (Ca2+)-regulated nuclear scaffold protease (CRNSP), as reported in reference [1].Formula:C26H30ClN3O5Color and Shape:SolidMolecular weight:499.99AE-3763
CAS:AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).Formula:C23H34F3N5O7Purity:98%Color and Shape:SolidMolecular weight:549.54Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Color and Shape:Odour SolidRef: TM-L1100
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireα-Methyl-DL-aspartic acid
CAS:α-Methyl-DL-aspartic acid specifically inhibits argininosuccinate synthase (ASS), the rate-limiting enzyme in 1-citrulline-to-1-arginine recycling.Formula:C5H9NO4Purity:99.91%Color and Shape:SolidMolecular weight:147.13CDD-3290
CDD-3290 serves as a functional therapeutic tool specifically designed to enable the precise detection and inhibition of the proteolytic activity of PSA which plays a pivotal role in the progression of prostate cancer during strictly monitored laboratory observation periods and molecular investigations to evaluate the pharmacological potential of targeted kallikrein inhibition in specialized preclinical research environments.Formula:C17H14N6O2Purity:99.13%Color and Shape:White SolidMolecular weight:334.33Lonodelestat TFA
Lonodelestat TFA, an oral peptide, selectively inhibits hNE, potentially aiding in CF research.Formula:C73H112F3N15O21Color and Shape:SolidMolecular weight:1592.75Tiprelestat
CAS:Tiprelestat: strong inhibitor of human neutrophil elastase, anti-inflammatory, antimicrobial, used in inflammation/immune research.Formula:C254H416N72O75S10Color and Shape:SolidMolecular weight:5999.09MeOSuc-AAPA-CMK
MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].Formula:C20H31ClN4O8Color and Shape:SolidMolecular weight:490.94α 1 Antichymotrypsin, Human Plasma
CAS:Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.Color and Shape:SolidRoseltide rT1
CAS:Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 μM) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8). It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.Formula:C110H177N31O31S6Color and Shape:SolidMolecular weight:2622.16Tilpisertib fosmecarbil TFA
CAS:Tilpisertib fosmecarbil TFA, the TFA salt form of Tilpisertib, acts as an inhibitor of serine/threonine kinases. This compound also exhibits anti-inflammatory activity.Formula:C37H37ClF3N8O9PColor and Shape:SolidMolecular weight:861.16Phosphorylase Kinase β-Subunit Fragment (420-436)
CAS:Phosphorylase Kinase β-Subunit Fragment (420-436) is a peptide fragment (430-436) derived from the β-Subunit of phosphorylase kinase.Formula:C79H131N31O25SPurity:98%Color and Shape:SolidMolecular weight:1947.14Activated Protein C (390-404), human
CAS:Human Activated Protein C (390-404) peptide derived from serine protease, suppresses APC anticoagulation.Formula:C91H130N22O23Purity:98%Color and Shape:SolidMolecular weight:1900.14SFTI-1
CAS:SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.Formula:C67H104N18O18S2Color and Shape:SolidMolecular weight:1513.78Dansyl-Glu-Gly-Arg-Chloromethylketone
CAS:Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activatedFormula:C26H36ClN7O7SColor and Shape:SolidMolecular weight:626.12KKI-5
CAS:KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.Formula:C35H55N11O9Purity:98%Color and Shape:SolidMolecular weight:773.88Nonacog alfa
CAS:Nonacog alfa (BAX326), a recombinant human factor IX, is utilized in the study of hemophilia B [1].Color and Shape:LiquidMeOSuc-AAPF-CMK
CAS:MeOSuc-AAPF-CMK (MeOSuc-Ala-Ala-Pro-Phe-CH2Cl) is a potent inhibitor of the enzyme proteinase K [1].Formula:C26H35ClN4O7Color and Shape:SolidMolecular weight:551.03Suc-AAP-Abu-pNA
CAS:Suc-AAP-Abu-pNA is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,Formula:C25H34N6O9Color and Shape:SolidMolecular weight:562.57C1 Esterase Inhibitor (Human)
C1 Esterase Inhibitor (Human) is a glycoprotein derived from human plasma and acts as a serine protease inhibitor. It inactivates enzymes like C1r, C1s, and mannose-binding lectin-associated serine proteases (MASP) through covalent binding. This compound possesses anti-inflammatory properties and is utilized to prevent angioedema attacks associated with hereditary angioedema.Color and Shape:Odour LiquidChymotrypsinogen
CAS:Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .Color and Shape:SolidPKR-IN-C51
CAS:PKR-IN-C51 is ATP-competitive protein kinase R (PKR) inhibitor that inhibits intracellular PKR activation and autophosphorylation. Ser/Thr kinase.Formula:C23H21N5Purity:98.94%Color and Shape:Yellow SolidMolecular weight:367.45Ref: TM-T24647
2mg82.00€5mg120.00€1mL*10mM (DMSO)133.00€10mg192.00€25mg356.00€50mg530.00€100mg755.00€2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
CAS:2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urineFormula:C13H16O3Purity:99.53% - 99.81%Color and Shape:SolidMolecular weight:220.26Ref: TM-T8802
1mg82.00€1mL*10mM (DMSO)146.00€5mg168.00€10mg244.00€25mg404.00€50mg567.00€100mg767.00€500mg1,521.00€WNK463
CAS:WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).Formula:C21H24F3N7O2Purity:>99.99% - ≥95%Color and Shape:SolidMolecular weight:463.46Benzamidine hydrochloride
CAS:Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.Formula:C7H9ClN2Purity:99.64% - 99.97%Color and Shape:SolidMolecular weight:156.612-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one
CAS:2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.Formula:C14H7BrClNO2Purity:97.36%Color and Shape:SolidMolecular weight:336.57ML281
CAS:ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.Formula:C22H19N3O2SPurity:99.12% - 99.87%Color and Shape:SolidMolecular weight:389.47Ref: TM-T3423
1mg34.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg92.00€25mg178.00€50mg295.00€100mg474.00€500mg1,035.00€WNK-IN-11
CAS:WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)Formula:C21H21Cl2N5OSPurity:98.32%Color and Shape:SolidMolecular weight:462.4Ref: TM-T5456
1mg87.00€5mg172.00€1mL*10mM (DMSO)188.00€10mg280.00€25mg474.00€50mg683.00€100mg964.00€500mg1,918.00€KKI-5 acetate(97145-43-2 free base)
KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.Formula:C37H59N11O11Purity:99.74%Color and Shape:White SolidMolecular weight:833.95Cetraxate hydrochloride
CAS:Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.Formula:C17H24ClNO4Purity:99.75%Color and Shape:SolidMolecular weight:341.83Alvelestat
CAS:Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.Formula:C25H22F3N5O4SPurity:98% - >99.99%Color and Shape:White SolidMolecular weight:545.53Ref: TM-T3107
1mg34.00€2mg43.00€5mg56.00€1mL*10mM (DMSO)74.00€10mg84.00€25mg148.00€50mg219.00€100mg349.00€500mg830.00€Lanadelumab
CAS:Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.Purity:95% - 97.4% (SDS-PAGE); 99.2% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:145.70 kDaAnti-Matriptase Antibody
Anti-Matriptase Antibody is a human antibody expressed in CHO cells.Purity:95.8% (SDS-PAGE); 99.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.2% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:144.27 kDaGalegenimab
CAS:Galegenimab (RG 6147) is an Fab targeting HtrA1, capable of blocking proteolytic cleavage of biglycan (an HtrA1 substrate), suitable for AMD research.Purity:95% - 95.8% (SDS-PAGE); 99.7% (SEC-HPLC)Color and Shape:Transparent LiquidMolecular weight:46.87 kDaMEGA-9
CAS:MEGA-9 (Nonanoyl-N-Methylglucamide) solubilizes membrane protein and can be used as a nonionic detergent.Formula:C16H33NO6Purity:99.9%Color and Shape:White SolidMolecular weight:335.44ZM223 hydrochloride (2031177-48-5 free base)
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.Formula:C23H18ClF3N4O2S2Purity:98%Color and Shape:SolidMolecular weight:538.99AGLME
CAS:AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.Formula:C11H21N3O4Color and Shape:SolidMolecular weight:259.3BMS-363131
CAS:BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.Formula:C28H40N6O5Purity:97.99%Color and Shape:SolidMolecular weight:540.65Lodelaben
CAS:Lodelaben (Declaben, SC-39026) is a reversible, non-competitive,specific inhibitor of human neutrophil elastase (HNE) with high potency (IC50=0.5 μM).Formula:C25H41ClO3Purity:99.62% - >99.99%Color and Shape:White SolidMolecular weight:425.04WNK1-IN-1
CAS:WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Formula:C13H15BrCl2N2O4SPurity:98.09%Color and Shape:SolidMolecular weight:446.14Ref: TM-T73295
1mg71.00€5mg152.00€1mL*10mM (DMSO)167.00€10mg236.00€25mg485.00€50mg782.00€100mg1,305.00€WNK-IN-11-D3
CAS:WNK-IN-12 is an effective, selective, and orally active WNK1 kinase inhibitor.Formula:C21H18Cl2D3N5OSColor and Shape:SolidMolecular weight:465.42APC 366
CAS:APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Formula:C22H28N6O4Purity:99.8%Color and Shape:Yellow SolidMolecular weight:440.5IPR-803
CAS:IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.Formula:C27H23N3O4Purity:95%Color and Shape:Red SolidMolecular weight:453.49ZD8321
CAS:ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).Formula:C18H28F3N3O5Purity:98%Color and Shape:SolidMolecular weight:423.43ZD-0892
CAS:ZD-0892: potent, selective neutrophil elastase inhibitor; Ki 6.7 nM (human), 200 nM (porcine).Formula:C24H32F3N3O5Purity:95% - 99.53%Color and Shape:SolidMolecular weight:499.52AZD-9819
CAS:AZD-9819 is a neutrophil elastase (HNE) inhibitor applicable for research into chronic obstructive pulmonary disease (COPD).Formula:C25H19F3N6O2Purity:100% - 99.18%Color and Shape:Yellow SolidMolecular weight:492.45
