Cysteine Protease
Cysteine Protease inhibitors are compounds that target and inhibit cysteine proteases, a class of enzymes that break down proteins by cleaving peptide bonds in which a cysteine residue acts as the nucleophile. These enzymes are involved in various physiological processes, including apoptosis, immune response, and protein turnover. Cysteine protease inhibitors are crucial for studying diseases such as cancer, neurodegenerative disorders, and parasitic infections. At CymitQuimica, we provide cysteine protease inhibitors to aid your research in proteolysis, cellular regulation, and drug discovery.
Found 111 products of "Cysteine Protease"
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L-873724
CAS:L-873724: Selective, reversible cathepsin K inhibitor; IC50s—cat K: 0.2 nM, cat S: 178 nM, cat L: 264 nM, cat B: 5239 nM; inhibits bone resorption.Formula:C23H26F3N3O3SPurity:98%Color and Shape:SolidMolecular weight:481.53CAA0225
CAS:CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.Formula:C28H29N3O5Color and Shape:SolidMolecular weight:487.55MDL 27399
CAS:MDL 27399 suppresses human neutrophil cathepsin G.Formula:C26H36N4O8Color and Shape:SolidMolecular weight:532.59AM 4299 B
CAS:AM 4299 B is a novel inhibitor of a thiol protease.Formula:C16H27N3O7Purity:98%Color and Shape:SolidMolecular weight:373.4Cysteine Protease inhibitor hydrochloride
CAS:Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.Formula:C18H15ClN4OPurity:98%Color and Shape:SolidMolecular weight:338.79NAAA-IN-2
CAS:NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.Formula:C11H13N3O2SColor and Shape:SolidMolecular weight:251.3SSAA09E1
CAS:SSAA09E1 blocks SARS-CoV entry, lowers ACE2-mediated HEK293T cell infection (EC50 = 6.7 μM), and inhibits cathepsin L (IC50 = 5.33 μM).Formula:C7H9N3S2Color and Shape:SolidMolecular weight:199.3SQ 32602
CAS:SQ 32602 is a cathepsin E inhibitor.Formula:C32H52N3O7PColor and Shape:SolidMolecular weight:621.74GSK2793660 free base
CAS:GSK-2793660, a cathepsin C inhibitor, may treat cystic fibrosis and related lung conditions.Formula:C22H31N3O3Color and Shape:SolidMolecular weight:385.5Dutacatib
CAS:Dutacatib is an inhibitor of SARS-CoV-2 3CLpro and cathepsin K, offering antiviral properties and potential benefits in treating cancer-induced bone disease.
Formula:C23H31N7OColor and Shape:SolidMolecular weight:421.54Cysteine protease inhibitor-2
CAS:Cysteine protease inhibitor from US20070032499A1; halts DCT116 at 6.5μM, PC3 at 4.4μM.Formula:C13H5N5OPurity:98%Color and Shape:SolidMolecular weight:247.21Kgp-IN-1
CAS:Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.Formula:C19H24F4N4O3Purity:98%Color and Shape:SolidMolecular weight:432.41Calpain Inhibitor XII
CAS:Calpain Inhibitor XII (Z-L-Nva-CONH-CH2-2-Py) is a calpain I inhibitor that inhibits calpain II and cathepsin B.
Formula:C26H34N4O5Color and Shape:SolidMolecular weight:482.57LHVS
CAS:LHVS effectively blocks T.
Formula:C28H37N3O5SPurity:98%Color and Shape:SolidMolecular weight:527.68CA 074
CAS:CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates
Formula:C18H29N3O6Purity:97.80%Color and Shape:SolidMolecular weight:383.44Oxocarbazate
CAS:Oxocarbazate (CID23631927) is a subnanomolar, reversible cathepsin L inhibitor, also reducing SARS-CoV and Ebola virus entry into human cells.Formula:C28H33N5O6Color and Shape:SolidMolecular weight:535.59LmCPB-IN-1
CAS:LmCPB-IN-1, compound 35, is a reversible inhibitor of LmCPB with strong binding (pKi 9.7).Formula:C18H30N6O2Color and Shape:SolidMolecular weight:362.47DTS
CAS:DTS is a selective and isoform-specific RSK1 kinase inhibitor. It also has broad cancer therapeutic potential.Formula:C14H14S3Purity:98%Color and Shape:SolidMolecular weight:278.46Cathepsin L/S-IN-1
Cathepsin L/S-IN-1 inhibits Cathepsin L & S (IC50: 4.10 & 1.79 μM) and reduces metastasis in pancreatic cancer cells.Formula:C29H33BrN4O4SColor and Shape:SolidMolecular weight:613.57JPM-OEt
CAS:JPM-OEt: broad-spectrum, covalent cysteine cathepsin inhibitor with antitumor effects.Formula:C20H28N2O6Purity:98%Color and Shape:SolidMolecular weight:392.45Calpain-2-IN-1
CAS:Calpain-2-IN-1 is a selective calpain-2 inhibitor with Ki values of 181 nM for calpain-1 and 7.8 nM for calpain-2, applicable for neurodegenerative diseases a.Formula:C28H37N3O7Color and Shape:SolidMolecular weight:527.61GSK-2793660
CAS:GSK-2793660, an oral, irreversible CTSC inhibitor, aids bronchiectasis research.Formula:C20H27N3O3Purity:98%Color and Shape:SolidMolecular weight:357.45Gü1303
CAS:Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).Formula:C20H22N4O3Color and Shape:SolidMolecular weight:366.41Cysteine Protease inhibitor
CAS:Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine ProteaseFormula:C18H14N4OPurity:98%Color and Shape:SolidMolecular weight:302.33Cathepsin X-IN-1
CAS:Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].
Formula:C15H13N3O3SPurity:99.34%Color and Shape:SolidMolecular weight:315.35JNJ-10311795
CAS:JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.Formula:C40H35N2O6PPurity:97.43%Color and Shape:SolidMolecular weight:670.69Cathepsin Inhibitor 2
CAS:Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).Formula:C19H21F6N3OPurity:98%Color and Shape:SolidMolecular weight:421.38SQ 32056
CAS:SQ 32056 is a cathepsin E inhibitor.Formula:C37H56N4O5Purity:98%Color and Shape:SolidMolecular weight:636.86ABP 25
CAS:ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.Formula:C55H66ClN5O3Color and Shape:SolidMolecular weight:880.6Cathepsin K inhibitor 3
CAS:Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.Formula:C30H31FN4O4SColor and Shape:SolidMolecular weight:562.65MeOSuc-AAPV-CMK
CAS:MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediatedFormula:C22H35ClN4O7Color and Shape:SolidMolecular weight:502.99SPR38
SPR38: SARS-CoV-2 protease inhibitor with Ki 0.260 μM; also blocks hCatL (Ki 1.92 μM) and hCatB (Ki 11.1 μM).Formula:C24H33N3O5Color and Shape:SolidMolecular weight:443.54SID 26681509
CAS:SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).Formula:C27H33N5O5SPurity:99.18%Color and Shape:SolidMolecular weight:539.65Ref: TM-T12909
1mg63.00€5mg137.00€10mg205.00€25mg414.00€50mg618.00€100mg882.00€1mL*10mM (DMSO)163.00€Petesicatib
CAS:Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.Formula:C25H23F6N5O4SPurity:99.76%Color and Shape:SolidMolecular weight:603.54Ref: TM-T16474
1mg100.00€5mg236.00€10mg371.00€25mg735.00€50mg1,134.00€100mg1,468.00€200mg1,972.00€1mL*10mM (DMSO)314.00€(Rac)-Neurodegenerative Disorder-Targeting Compound 1
CAS:(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.Formula:C28H28N4O4Color and Shape:SolidMolecular weight:484.55Z-FG-NHO-BzOME
CAS:Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,Formula:C27H27N3O7Color and Shape:SolidMolecular weight:505.52Z-LVG
CAS:Z-LVG, an irreversible cysteine protease inhibitor and a tripeptide derivative of cystatin C, serves as an inhibitor of viral replication and is utilized inFormula:C21H31N3O6Color and Shape:SolidMolecular weight:421.49MPI8
CAS:MPI8 is a SARS-CoV-2 Protease inhibitor (IC50 = 105 nM).Formula:C32H48N4O7Color and Shape:SolidMolecular weight:600.75Z-DEVD-CMK
CAS:Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].Formula:C27H35ClN4O12Color and Shape:SolidMolecular weight:643.04MK-0674
CAS:MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.Formula:C26H27F6N3O2Purity:97.3% - 99.91%Color and Shape:SolidMolecular weight:527.5VBY-825
CAS:VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.Formula:C23H29F4N3O5SPurity:99.91%Color and Shape:SolidMolecular weight:535.55Cathepsin C-IN-3
Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).Formula:C28H21F3N6OSColor and Shape:SolidMolecular weight:546.57SID 26681509 quarterhydrate
SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).Formula:C27H35N5O6SColor and Shape:SolidMolecular weight:544.16RO5461111
CAS:RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.Formula:C27H24F6N4O4SColor and Shape:SolidMolecular weight:614.56Cathepsin C-IN-5
CAS:Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.
Formula:C21H17ClN6OSColor and Shape:SolidMolecular weight:436.92Z-FY-CHO
CAS:Pyridoxal (Pyridoxaldehyde), a component of vitamin B6, is an aldehyde obtained by oxidizing pyridoxine and is widely found in plants and animals.Formula:C26H26N2O5Purity:95.88%Color and Shape:SolidMolecular weight:446.5SAR-114137
CAS:SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.Formula:C25H34N4O7SPurity:99.09% - 99.91%Color and Shape:SolidMolecular weight:534.63CatD-IN-1
CAS:CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM, and it shows potential for research in the field of osteoarthritis.Formula:C18H18Cl2N4O5Color and Shape:SolidMolecular weight:441.265CTSL/CAPN1-IN-2
CAS:CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].Formula:C34H40N4O6Color and Shape:SolidMolecular weight:600.7Cathepsin C-IN-4
Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).Formula:C21H14ClF3N4SColor and Shape:SolidMolecular weight:446.88
