
Cysteine Protease
Cysteine Protease inhibitors are compounds that target and inhibit cysteine proteases, a class of enzymes that break down proteins by cleaving peptide bonds in which a cysteine residue acts as the nucleophile. These enzymes are involved in various physiological processes, including apoptosis, immune response, and protein turnover. Cysteine protease inhibitors are crucial for studying diseases such as cancer, neurodegenerative disorders, and parasitic infections. At CymitQuimica, we provide cysteine protease inhibitors to aid your research in proteolysis, cellular regulation, and drug discovery.
Found 96 products of "Cysteine Protease"
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VEL-0230
CAS:<p>VEL-0230 (NC-2300) is a cathespin K inhibitor boosting bone growth and reducing loss, targeting bone diseases and developed by Velcura Therapeutics.</p>Formula:C14H24NNaO5Color and Shape:SolidMolecular weight:309.33ASPER-29
CAS:<p>ASPER-29, an Asperphenamate analog, inhibits cathepsins L/S with IC50s of 6.03/5.02 μM, useful in cancer migration/invasion research.</p>Formula:C31H29BrN2O5SColor and Shape:SolidMolecular weight:621.54L-873724
CAS:<p>L-873724: Selective, reversible cathepsin K inhibitor; IC50s—cat K: 0.2 nM, cat S: 178 nM, cat L: 264 nM, cat B: 5239 nM; inhibits bone resorption.</p>Formula:C23H26F3N3O3SPurity:98%Color and Shape:SolidMolecular weight:481.53CAA0225
CAS:<p>CAA0225 is a selective inhibitor of cathepsin L. CAA0225 is a probe for autophagic proteolysis.</p>Formula:C28H29N3O5Color and Shape:SolidMolecular weight:487.55MDL 27399
CAS:<p>MDL 27399 suppresses human neutrophil cathepsin G.</p>Formula:C26H36N4O8Color and Shape:SolidMolecular weight:532.59AM 4299 B
CAS:<p>AM 4299 B is a novel inhibitor of a thiol protease.</p>Formula:C16H27N3O7Purity:98%Color and Shape:SolidMolecular weight:373.4Cysteine Protease inhibitor hydrochloride
CAS:<p>Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.</p>Formula:C18H15ClN4OPurity:98%Color and Shape:SolidMolecular weight:338.79NAAA-IN-2
CAS:<p>NAAA-IN-2, a selective inhibitor with 50 nM IC50, targets NAAA, an enzyme hydrolyzing PEA/OEA, and may aid inflammation and pain studies.</p>Formula:C11H13N3O2SColor and Shape:SolidMolecular weight:251.3SSAA09E1
CAS:<p>SSAA09E1 blocks SARS-CoV entry, lowers ACE2-mediated HEK293T cell infection (EC50 = 6.7 μM), and inhibits cathepsin L (IC50 = 5.33 μM).</p>Formula:C7H9N3S2Color and Shape:SolidMolecular weight:199.3SQ 32602
CAS:<p>SQ 32602 is a cathepsin E inhibitor.</p>Formula:C32H52N3O7PColor and Shape:SolidMolecular weight:621.74Dutacatib
CAS:<p>Dutacatib is an inhibitor of SARS-CoV-2 3CLpro and cathepsin K, offering antiviral properties and potential benefits in treating cancer-induced bone disease.</p>Formula:C23H31N7OColor and Shape:SolidMolecular weight:421.54Cysteine protease inhibitor-2
CAS:<p>Cysteine protease inhibitor from US20070032499A1; halts DCT116 at 6.5μM, PC3 at 4.4μM.</p>Formula:C13H5N5OPurity:98%Color and Shape:SolidMolecular weight:247.21Kgp-IN-1
CAS:<p>Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.</p>Formula:C19H24F4N4O3Purity:98%Color and Shape:SolidMolecular weight:432.41LHVS
CAS:<p>LHVS effectively blocks T.</p>Formula:C28H37N3O5SPurity:98%Color and Shape:SolidMolecular weight:527.68CA 074
CAS:<p>CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates</p>Formula:C18H29N3O6Purity:97.80%Color and Shape:SolidMolecular weight:383.44Cathepsin X-IN-1
CAS:<p>Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].</p>Formula:C15H13N3O3SPurity:99.34%Color and Shape:SolidMolecular weight:315.35JNJ-10311795
CAS:<p>JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.</p>Formula:C40H35N2O6PPurity:97.43%Color and Shape:SolidMolecular weight:670.69SPR38
<p>SPR38: SARS-CoV-2 protease inhibitor with Ki 0.260 μM; also blocks hCatL (Ki 1.92 μM) and hCatB (Ki 11.1 μM).</p>Formula:C24H33N3O5Color and Shape:SolidMolecular weight:443.54Cathepsin K inhibitor 3
CAS:<p>Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.</p>Formula:C30H31FN4O4SColor and Shape:SolidMolecular weight:562.65ABP 25
CAS:<p>ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.</p>Formula:C55H66ClN5O3Color and Shape:SolidMolecular weight:880.6SQ 32056
CAS:<p>SQ 32056 is a cathepsin E inhibitor.</p>Formula:C37H56N4O5Purity:98%Color and Shape:SolidMolecular weight:636.86Cathepsin Inhibitor 2
CAS:<p>Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).</p>Formula:C19H21F6N3OPurity:98%Color and Shape:SolidMolecular weight:421.38MPI8
CAS:<p>MPI8 is a SARS-CoV-2 Protease inhibitor (IC50 = 105 nM).</p>Formula:C32H48N4O7Color and Shape:SolidMolecular weight:600.75Z-DEVD-CMK
CAS:<p>Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].</p>Formula:C27H35ClN4O12Color and Shape:SolidMolecular weight:643.04Petesicatib
CAS:<p>Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.</p>Formula:C25H23F6N5O4SPurity:99.76%Color and Shape:SolidMolecular weight:603.54MeOSuc-AAPV-CMK
CAS:<p>MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated</p>Formula:C22H35ClN4O7Color and Shape:SolidMolecular weight:502.99Z-FG-NHO-BzOME
CAS:<p>Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,</p>Formula:C27H27N3O7Color and Shape:SolidMolecular weight:505.52SID 26681509
CAS:<p>SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).</p>Formula:C27H33N5O5SPurity:98.16%Color and Shape:SolidMolecular weight:539.65MK-0674
CAS:<p>MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.</p>Formula:C26H27F6N3O2Purity:97.3% - 99.91%Color and Shape:SolidMolecular weight:527.5VBY-825
CAS:<p>VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.</p>Formula:C23H29F4N3O5SPurity:99.91%Color and Shape:SolidMolecular weight:535.55GB111-NH2
CAS:<p>GB111-NH2, a cysteine cathepsin inhibitor, is applicable in cancer research [1].</p>Formula:C33H39N3O6Color and Shape:SolidMolecular weight:573.68Verducatib
CAS:<p>Verducatib is an inhibitor of cathepsins (cathepsin).</p>Formula:C31H35FN4O3Color and Shape:SolidMolecular weight:530.633Cathepsin K inhibitor 2
CAS:<p>Cathepsin K inhibitor 2 targets CTSK gene, may treat osteoporosis and osteoarthritis, detailed in patent WO2021147882A1.</p>Formula:C30H33F4N5O3Color and Shape:SolidMolecular weight:587.61BI-1915
CAS:<p>BI-1915 is a selective inhibitor of Cathepsin S, with an IC50 of 17 nM. It is utilized in the research of autoimmune diseases.</p>Formula:C21H37N5O3Color and Shape:SolidMolecular weight:407.55Cathepsin C-IN-3
<p>Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).</p>Formula:C28H21F3N6OSColor and Shape:SolidMolecular weight:546.57RO5461111
CAS:<p>RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.</p>Formula:C27H24F6N4O4SColor and Shape:SolidMolecular weight:614.56SID 26681509 quarterhydrate
<p>SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).</p>Formula:C27H35N5O6SColor and Shape:SolidMolecular weight:544.16Dual Cathepsin L/JAK-IN-1
CAS:<p>DualCathepsinL/JAK-IN-1 (Compound A8) serves as a dual inhibitor of Cathepsin L (CTSL) and JAK, exhibiting IC50 values of 0.68 μM for CTSL and 337.1 nM, 5.251 nM, 27.29 nM, and 172.6 nM for JAK1/2/3 and TYK2, respectively. This compound effectively prevents the activation of MAPK, NF-κB, and JAK/STAT signaling pathways, leading to significant anti-inflammatory therapeutic effects. DualCathepsinL/JAK-IN-1 is applicable in research on acute lung injury (ALI).</p>Formula:C19H18ClN5Color and Shape:SolidMolecular weight:351.833Cathepsin C-IN-5
CAS:<p>Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.</p>Formula:C21H17ClN6OSColor and Shape:SolidMolecular weight:436.92Z-FY-CHO
CAS:<p>Pyridoxal (Pyridoxaldehyde), a component of vitamin B6, is an aldehyde obtained by oxidizing pyridoxine and is widely found in plants and animals.</p>Formula:C26H26N2O5Purity:95.88%Color and Shape:SolidMolecular weight:446.5CTSL/CAPN1-IN-2
CAS:<p>CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].</p>Formula:C34H40N4O6Color and Shape:SolidMolecular weight:600.7CatD-IN-1
CAS:<p>CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM, and it shows potential for research in the field of osteoarthritis.</p>Formula:C18H18Cl2N4O5Color and Shape:SolidMolecular weight:441.265Cathepsin C-IN-4
<p>Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM).</p>Formula:C21H14ClF3N4SColor and Shape:SolidMolecular weight:446.88MIV-247
CAS:<p>MIV-247 is a cathepsin S inhibitor that attenuates mechanically abnormal pain in preclinical neuropathic pain models and can be used to study myocardial injury.</p>Formula:C17H24F3N3O4Purity:99.27%Color and Shape:SolidMolecular weight:391.39PD 151746
CAS:<p>PD151746: calpain inhibitor, Ki μ-calpain=0.26μM, Ki m-calpain=5.33μM; reduces oxLDL cytotoxicity.</p>Formula:C11H8FNO2SPurity:98.63% - ≥95%Color and Shape:SolidMolecular weight:237.25ALLM
CAS:<p>ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].</p>Formula:C19H35N3O4SPurity:98%Color and Shape:White PowderMolecular weight:401.56

