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Cysteine Protease

Cysteine Protease

Cysteine Protease inhibitors are compounds that target and inhibit cysteine proteases, a class of enzymes that break down proteins by cleaving peptide bonds in which a cysteine residue acts as the nucleophile. These enzymes are involved in various physiological processes, including apoptosis, immune response, and protein turnover. Cysteine protease inhibitors are crucial for studying diseases such as cancer, neurodegenerative disorders, and parasitic infections. At CymitQuimica, we provide cysteine protease inhibitors to aid your research in proteolysis, cellular regulation, and drug discovery.

Found 144 products for "Cysteine Protease".

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  • Cathepsin X-IN-1

    CAS:
    Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].
    Formula:C15H13N3O3S
    Purity:99.34%
    Color and Shape:White Solid
    Molecular weight:315.347
  • JNJ-10311795

    CAS:
    JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.
    Formula:C40H35N2O6P
    Purity:97.43%
    Color and Shape:Solid
    Molecular weight:670.69
  • Alicapistat

    CAS:
    Alicapistat (ABT-957) calpain 1/2 inhibitor investigated in Alzheimer’s disease; used in neurodegeneration, proteolysis, and neuronal injury mechanism studies.
    Formula:C25H27N3O4
    Purity:97.22%
    Color and Shape:Solid
    Molecular weight:433.4996
  • Neurodegenerative Disorder-Targeting Compound 1

    CAS:
    Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].
    Formula:C28H28N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:484.55
  • Z-DEVD-CMK

    CAS:
    Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].
    Formula:C27H35ClN4O12
    Color and Shape:Solid
    Molecular weight:643.04
  • Cathepsin K inhibitor 3

    CAS:
    Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.
    Formula:C30H31FN4O4S
    Color and Shape:Solid
    Molecular weight:562.65
  • MPI8

    CAS:
    MPI8 is a SARS-CoV-2 Protease inhibitor (IC50 = 105 nM).
    Formula:C32H48N4O7
    Color and Shape:Solid
    Molecular weight:600.75
  • Cathepsin Inhibitor 2

    CAS:
    Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).
    Formula:C19H21F6N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.38
  • SPR38


    SPR38: SARS-CoV-2 protease inhibitor with Ki 0.260 μM; also blocks hCatL (Ki 1.92 μM) and hCatB (Ki 11.1 μM).
    Formula:C24H33N3O5
    Color and Shape:Solid
    Molecular weight:443.54
  • (Rac)-Neurodegenerative Disorder-Targeting Compound 1

    CAS:
    (Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.
    Formula:C28H28N4O4
    Color and Shape:Solid
    Molecular weight:484.55
  • SQ 32056

    CAS:
    SQ 32056 is a cathepsin E inhibitor.
    Formula:C37H56N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:636.86
  • Z-LVG

    CAS:
    Z-LVG, an irreversible cysteine protease inhibitor and a tripeptide derivative of cystatin C, serves as an inhibitor of viral replication and is utilized in
    Formula:C21H31N3O6
    Color and Shape:Solid
    Molecular weight:421.49
  • Z-FG-NHO-BzOME

    CAS:
    Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,
    Formula:C27H27N3O7
    Color and Shape:Solid
    Molecular weight:505.52
  • VK13


    VK13 (Compound 6) is a potent inhibitor of human cathepsin L (hCatL) and SARS-CoV-2 3CLpro (3CL-PR), with Ki values of 2.6 nM and 0.55 nM, respectively. It also exhibits activity against CoV-2, with an EC50 value of 1.25 μM.
    Formula:C24H28N4O5
    Color and Shape:Solid
    Molecular weight:452.503
  • SID 26681509

    CAS:
    SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).
    Formula:C27H33N5O5S
    Purity:99.18%
    Color and Shape:White Solid
    Molecular weight:539.65
  • MeOSuc-AAPV-CMK

    CAS:
    MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated
    Formula:C22H35ClN4O7
    Color and Shape:Solid
    Molecular weight:502.99
  • Petesicatib

    CAS:
    Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.
    Formula:C25H23F6N5O4S
    Purity:99.76% - 99.86%
    Color and Shape:Solid
    Molecular weight:603.537
  • ABP 25

    CAS:
    ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.
    Formula:C55H66ClN5O3
    Color and Shape:Solid
    Molecular weight:880.6
  • MK-0674

    CAS:
    MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.
    Formula:C26H27F6N3O2
    Purity:99.59% - 99.99%
    Color and Shape:White Solid
    Molecular weight:527.5
  • VBY-825

    CAS:
    VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.
    Formula:C23H29F4N3O5S
    Purity:99.91%
    Color and Shape:White Solid
    Molecular weight:535.55