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DPP-4

DPP-4

DPP-4 inhibitors are compounds that inhibit Dipeptidyl Peptidase-4, an enzyme involved in the inactivation of incretin hormones, which regulate glucose metabolism. By inhibiting DPP-4, these compounds help prolong the action of incretin hormones, enhancing insulin secretion and reducing blood glucose levels. DPP-4 inhibitors are widely used in the treatment of type 2 diabetes and in research focused on metabolic disorders. At CymitQuimica, we offer DPP-4 inhibitors to support your research in endocrinology, diabetes management, and metabolic disease.

Found 94 products for "DPP-4".

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  • Retagliptin Phosphate

    CAS:
    Retagliptin Phosphate (SP 2086) is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.
    Formula:C19H21F6N4O7P
    Purity:98.70%
    Color and Shape:Solid
    Molecular weight:562.3568
  • Begelomab

    CAS:
    Begelomab (SAND-26) is a mouse-derived monoclonal antibody targeting DPP-4/CD26. Begelomab can be used to study severe refractory inflammatory myopathies.
    Purity:97.8% (SDS-PAGE); 98.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 98.3% (SEC-HPLC)
    Color and Shape:Transparent Liquid
    Molecular weight:146.20 kDa (Predicted)
  • DBPR108

    CAS:
    DBPR108 is an orally bioavailable dipeptide-derived DPP4 inhibitor (IC50: 15 nM) and it has no inhibition on DDP8 and DPP9.
    Formula:C16H25FN4O2
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:324.3937
  • Denagliptin

    CAS:
    Denagliptin is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor for the treatment of endocrine Ü metabolic diseases and can be used in the study of
    Formula:C20H18F3N3O
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:373.3716
  • Saxagliptin hydrate

    CAS:
    Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).
    Formula:C18H27N3O3
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:333.4253
  • Trelagliptin

    CAS:
    Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.
    Formula:C18H20FN5O2
    Purity:98.88%
    Color and Shape:Solid
    Molecular weight:357.3821
  • Fotagliptin

    CAS:
    Fotagliptin is a dipeptidyl peptidase IV inhibitor.
    Formula:C17H19FN6O
    Color and Shape:Solid
    Molecular weight:342.37
  • Linagliptin Methyldimer

    CAS:
    Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.
    Formula:C50H56N16O4
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:945.0844
  • AMG-222

    CAS:
    AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.
    Formula:C32H39N9O3
    Color and Shape:Solid
    Molecular weight:597.71
  • (-)-Sitagliptin Carbamoyl Glucuronide

    CAS:
    Minor phase II metabolite of DPP-4 inhibitor sitagliptin, found in rat and dog plasma.
    Formula:C23H23F6N5O9
    Color and Shape:Solid
    Molecular weight:627.453
  • DPP-4/GPR119 modulator 1

    CAS:
    Orally active DPP-4 inhibitor/GPR119 agonist, Compound 22 lowers glucose, moderate hERG inhibition, IC50 4.9 µM, for diabetes research.
    Formula:C30H39ClN10O3
    Color and Shape:Solid
    Molecular weight:623.15
  • Sitagliptin fenilalanil hydrochloride

    CAS:
    Sitagliptin fenilalanil hydrochloride is an orally active DPP-4 inhibitor. Sitagliptin fenilalanil hydrochloride is used in diabetes research.
    Formula:C25H25ClF6N6O2
    Purity:98.32%
    Color and Shape:White Solid
    Molecular weight:590.95
  • 5-Hydroxy saxagliptin hydrochloride


    5-Hydroxy saxagliptin hydrochloride is the active metabolite of Saxagliptin and serves as a potent and selective DPP-4 inhibitor. The Ki values for 5-Hydroxy saxagliptin hydrochloride are 2.6 nM in humans and 2.9 nM in cynomolgus monkeys. This compound is applicable in the research of type 2 diabetes.
  • Talabostat isomer mesylate


    Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).
    Formula:C10H23BN2O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:310.18
  • SGLT2-IN-6


    SGLT2-IN-6 (Compound 101) is an orally active SGLT2 inhibitor with IC₅₀ values of 0.8 nM, 6.7 nM, and 72 nM for SGLT2, SGLT1, and DPP4, respectively. In diabetic rat models, SGLT2-IN-6 controls blood glucose levels and increases active GLP-1 levels. It is suitable for research on type 2 diabetes.
  • HAEGT

    CAS:
    HAEGT is the first N-terminal 1-5 residues of GLP-1 peptide.
    Formula:C20H31N7O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:513.5016
  • SGLT2-IN-5


    SGLT2-IN-5 (Compound 99) is an orally active SGLT2 inhibitor with IC₅₀ values of 0.8 nM for SGLT2, 23 nM for SGLT1, and 58 nM for DPP4. In diabetic rat models, SGLT2-IN-5 effectively regulates blood glucose and increases the levels of active GLP-1. It is suitable for research on type 2 diabetes.
  • Dutogliptin tartrate

    CAS:
    Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.
    Formula:C14H26BN3O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:391.18
  • Ellipyrone A


    Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).
    Formula:C25H34O8
    Color and Shape:Solid
    Molecular weight:462.53
  • Camegliptin

    CAS:
    Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.
    Formula:C20H28FN3O3
    Color and Shape:Solid
    Molecular weight:377.45