Protease-activated Receptor
Protease-activated Receptor (PAR) inhibitors are compounds that target and inhibit the activity of PARs, a family of G-protein-coupled receptors that are activated by proteolytic cleavage. These receptors play a role in various physiological processes, including coagulation, inflammation, and tissue repair. PAR inhibitors are valuable tools for studying the mechanisms of these processes and their involvement in diseases such as cancer, cardiovascular disorders, and chronic inflammation. At CymitQuimica, we provide PAR inhibitors to aid your research in signal transduction, immune response, and therapeutic discovery.
Found 54 products of "Protease-activated Receptor"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
FSLLRY-NH2 TFA(245329-02-6 free base)
<p>FSLLRY-NH2 TFA inhibits PAR2, reverses taxol-induced pain, and reduces itch in mice; blocks ERK and collagen in fibroblasts.</p>Formula:C41H61F3N10O10Purity:99.32%Color and Shape:SolidMolecular weight:910.99tcY-NH2 TFA(327177-34-4 free base)
<p>tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.</p>Formula:C42H50F3N7O9Purity:>99.99%Color and Shape:SolidMolecular weight:853.9Thrombin Receptor Activator for Peptide
<p>Thrombin Receptor Activator (TRAP) or Coagulation Factor II (1-5), used in CHD research.</p>Formula:C32H51F3N8O9Purity:99.88%Color and Shape:SolidMolecular weight:748.79Parmodulin 2
CAS:<p>ML161 (Parmodulin 2) inhibits PAR1, blocking platelet activation and thrombin-induced activity (IC50: 0.26μM).</p>Formula:C17H17BrN2O2Purity:97.35% - 99.95%Color and Shape:SolidMolecular weight:361.23AZ3451
CAS:<p>AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).</p>Formula:C30H27BrN4O3Purity:98.12%Color and Shape:SolidMolecular weight:571.46Protease-Activated Receptor-4 diTFA
<p>Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist</p>Formula:C37H48F6N8O11Purity:98.54%Color and Shape:SolidMolecular weight:894.812-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
<p>2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.</p>Formula:C38H64F3N11O10Purity:>99.99%Color and Shape:SolidMolecular weight:891.98ML-354
CAS:<p>ML354 is a selective antagonist of PAR4 with an IC 50 of 140 nM [1].</p>Formula:C16H14N2O3Purity:99.44%Color and Shape:SolidMolecular weight:282.29iso-TRAP-6
CAS:<p>iso-TRAP-6 (iso-SFLLRN), a hexapeptide made from isoserine instead of serine, is a PAR1 agonist that activates platelets via PAR-1.</p>Formula:C34H56N10O9Purity:98.55%Color and Shape:SolidMolecular weight:748.87PAR4 antagonist 3
CAS:<p>PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4). It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.</p>Formula:C22H16FN3O5SMolecular weight:453.44PAR-2-IN-2
CAS:<p>PAR-2-IN-2 (compound P-596) is an inhibitor of protease-activated receptor 2 (PAR-2), with an IC50 of 10.79 μM for SLIGKV and an IC50 greater than 200 μM for trypsin.</p>Formula:C25H20F3N5O2Color and Shape:SolidMolecular weight:479.454BMS-986141
CAS:<p>BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614</p>Formula:C27H23N5O5S2Purity:98.43% - 99.26%Color and Shape:SolidMolecular weight:561.63Protease-Activated Receptor-4
CAS:<p>Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.</p>Formula:C33H46N8O7Purity:98%Color and Shape:SolidMolecular weight:666.77TFLLR-NH2 2TFA(197794-83-5(free base))
<p>TFLLR-NH2 2TFA(197794-83-5(free base)) is an agonist of PAR1 (EC50 :1.9 μM).</p>Formula:C35H55F6N9O10Purity:99.56%Color and Shape:SolidMolecular weight:875.87
