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Stem Cells

Stem Cells

Stem cell inhibitors are compounds that specifically target stem cells and their signaling pathways, affecting their ability to self-renew and differentiate. These inhibitors are crucial in research focused on controlling stem cell behavior, understanding developmental processes, and developing therapies for diseases like cancer, where stem cells are thought to play a key role. At CymitQuimica, we offer a variety of stem cell inhibitors to support your research in regenerative medicine, developmental biology, and oncology.

Found 486 products of "Stem Cells"

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  • ROCK-IN-1
    Targetmol
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    ROCK-IN-1

    CAS:
    <p>ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological</p>
    Formula:C20H18FN3O
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:335.37

    Ref: TM-T13419

  • JAK-IN-3
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    JAK-IN-3

    CAS:
    <p>JAK-IN-3 is a potent JAK inhibitor that inhibits JAK3, JAK1, TYK2, and JAK2, and can be used for the study of immune system disorders.</p>
    Formula:C18H20N4O3
    Purity:98.04% - 98.19%
    Color and Shape:Solid
    Molecular weight:340.38

    Ref: TM-T11704

  • H-1152 dihydrochloride
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    H-1152 dihydrochloride

    CAS:
    <p>H-1152 2HCl: ROCK inhibitor, IC50=12 nM, Ki=1.6 nM. Blocks PKA, PKC, PKG, Aurora A, CaMKII with higher IC50s.</p>
    Formula:C16H23Cl2N3O2S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:392.34

    Ref: TM-T35328

  • GSK-3 inhibitor 1
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    GSK-3 inhibitor 1

    CAS:
    <p>GSK-3 inhibitor 1 is a GSK-3 inhibitor.</p>
    Formula:C22H17ClFN5O2
    Purity:98.42%
    Color and Shape:Solid
    Molecular weight:437.85

    Ref: TM-T11468

  • Londamocitinib
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    Londamocitinib

    CAS:
    <p>Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.</p>
    Formula:C28H31F2N7O4S
    Purity:98.64% - 99.56%
    Color and Shape:Solid
    Molecular weight:599.65

    Ref: TM-T11706

  • AZ-3
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    AZ-3

    CAS:
    <p>AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).</p>
    Formula:C20H28FN7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:385.48

    Ref: TM-T10424

  • TEAD-IN-1
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    TEAD-IN-1

    CAS:
    <p>TEAD-IN-1 (Compound 2) is an effective inhibitor of TEAD auto-palmitoylation with an IC50 of 603 nM. It enhances the interaction between TEAD and VGLL4, while diminishing the interaction between YAP and TEAD. TEAD-IN-1 is applicable for cancer research.</p>
    Formula:C15H20F2N2O3S
    Color and Shape:Solid
    Molecular weight:346.393

    Ref: TM-T204883

  • TEAD-IN-20
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    TEAD-IN-20

    CAS:
    <p>TEAD-IN-20 is a TEAD inhibitor with IC50 values of 0.021 μM in TEAD4 FRET and 0.044 μM in TEAD4 MCF7-Tead cell lines. It has potential applications in cancer research.</p>
    Formula:C20H19F3N4O3
    Color and Shape:Solid
    Molecular weight:420.39

    Ref: TM-T207373

  • Tyk2-IN-20
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    Tyk2-IN-20

    CAS:
    <p>Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 nM. Additionally, it inhibits JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is utilized for the research of inflammatory diseases.</p>
    Formula:C24H25N7O2
    Color and Shape:Solid
    Molecular weight:443.50

    Ref: TM-T201155

  • TGFβ1-IN-1
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    TGFβ1-IN-1

    CAS:
    <p>TGFβ1-IN-1 is a TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in cancer research.</p>
    Formula:C22H24N2O3
    Purity:99.89% - 99.89%
    Color and Shape:Solid
    Molecular weight:364.438

    Ref: TM-T61389

  • M3686
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    M3686

    CAS:
    <p>M3686 (Compound 29) is a potent and selective TEAD1 inhibitor with an IC50 value of 51 nM. It exhibits weaker binding activity toward TEAD3. M3686 significantly inhibits the cellular activity of YAP-dependent NCI-H226 cell lines, with an IC50 value of 0.06 μM, and demonstrates strong antitumor effects in the NCI-H226 xenograft model.</p>
    Formula:C21H18F3N5O2
    Color and Shape:Solid
    Molecular weight:429.395

    Ref: TM-T205477

  • CDD-1431
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    CDD-1431

    CAS:
    <p>CDD-1431 is a highly selective BMPR2 kinase inhibitor with a Kiapp of 20.6 nM. It inhibits BRE reporter gene activity, exhibiting an IC50 of 4.87 μM. BMPs regulate cellular processes across various tissue types such as the kidneys, skeletal muscle, heart, and reproductive organs, and can induce ectopic bone formation.</p>
    Formula:C33H38N8O5S
    Color and Shape:Solid
    Molecular weight:658.77

    Ref: TM-T205082

  • YLIU-4-105-1
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    YLIU-4-105-1

    CAS:
    <p>YLIU-4-105-1 is a type II JAK2 inhibitor. Demonstrating in vivo pharmacological activity, YLIU-4-105-1 reduces splenic weight, decreases blood reticulocyte counts in a dose-dependent manner, and inhibits pSTAT5.</p>
    Formula:C32H34F3N7O2
    Color and Shape:Solid
    Molecular weight:605.65

    Ref: TM-T201176

  • Cenacitinib
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    Cenacitinib

    CAS:
    <p>Cenacitinib is an effective inhibitor of Janus kinase (Janus kinase) and possesses anti-inflammatory activity.</p>
    Formula:C19H19F2N7O3
    Color and Shape:Solid
    Molecular weight:431.40

    Ref: TM-T201149

  • TEAD-IN-10
    Targetmol
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    TEAD-IN-10

    CAS:
    <p>TEAD-IN-10 (compound 15), a covalent inhibitor, exhibits selective and potent inhibitory activity against TEAD1 (IC 50 =14 nM), TEAD2 (IC 50 =179 nM), and TEAD3 (IC 50 =4 nM). This compound is utilized in cancer research [1].</p>
    Formula:C15H14F3NO
    Color and Shape:Solid
    Molecular weight:281.27

    Ref: TM-T87500

  • CDK8-IN-11
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    CDK8-IN-11

    CAS:
    <p>CDK8-IN-11 is a CDK8 inhibitor that demonstrates anti-proliferative activity against colon cancer cell lines and inhibits the activation of WNT/β-catenin.</p>
    Formula:C19H15F3N4O2
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:388.34

    Ref: TM-T61742

  • Carboxylesterase-IN-3
    Targetmol
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    Carboxylesterase-IN-3

    CAS:
    <p>Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.</p>
    Formula:C11H6Cl2N4OS
    Purity:97.49% - 98.47%
    Color and Shape:Solid
    Molecular weight:313.16

    Ref: TM-T60788

  • PMMB-187
    Targetmol
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    PMMB-187

    CAS:
    <p>PMMB-187, a selective STAT3 inhibitor, exhibits an IC50 of 1.81 μM in MDA-MB-231 cells. This compound induces apoptosis in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity and nuclear translocation, reducing mitochondrial membrane potential, increasing reactive oxygen species (ROS) production, and upregulating the expression of apoptosis-related proteins. PMMB-187 is useful for research in the field of cancer.</p>
    Formula:C27H23BrN2O6S2
    Color and Shape:Solid
    Molecular weight:615.52

    Ref: TM-T200126

  • AJI-214
    Targetmol
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    AJI-214

    CAS:
    <p>AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By directly inhibiting Aurora kinase A, AJI-214 prevents mitotic progression and cell polarity in T cells while concurrently suppressing JAK2 activation to reduce STAT3 phosphorylation. This inhibition decreases the differentiation of TH1 and TH17 cells. AJI-214 is utilized in research focused on the modulation of immune responses and the prevention of graft-versus-host disease (GVHD).</p>
    Formula:C17H13ClFN5O
    Color and Shape:Solid
    Molecular weight:357.77

    Ref: TM-T200387

  • dCK1α-2
    Targetmol
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    dCK1α-2

    <p>dCK1α-2 is an orally effective CK1α molecular glue (Molecular Glue) degrader that targets p53 pathway-related targets. It demonstrates antitumor efficacy in mouse models by enhancing the expression of p53-related genes.</p>
    Formula:C24H24ClN5O4
    Color and Shape:Solid
    Molecular weight:481.93

    Ref: TM-T201857