Stem Cells
Stem cell inhibitors are compounds that specifically target stem cells and their signaling pathways, affecting their ability to self-renew and differentiate. These inhibitors are crucial in research focused on controlling stem cell behavior, understanding developmental processes, and developing therapies for diseases like cancer, where stem cells are thought to play a key role. At CymitQuimica, we offer a variety of stem cell inhibitors to support your research in regenerative medicine, developmental biology, and oncology.
Found 129 products for "Stem Cells".
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HC-258
CAS:HC-258 is a direct TEAD inhibitor covalent Cys380, and reduces the transcriptional levels and inhibits the migration of CTGF, CYR61, AXL and NF2 MDA-MB-231.Formula:C20H24N2O2Color and Shape:Yellow SolidMolecular weight:324.42MSC-1254
MSC-1254 is a reversible, selective, and covalent inhibitor of TEAD1, primarily utilized in cancer research.Formula:C25H22F2N4O4SColor and Shape:SolidMolecular weight:512.53LY2382770
LY2382770 is a human monoclonal antibody (mAb) that specifically targets TGFB1. It is utilized in the study of diabetic nephropathy.TGF-β1/Smad3-IN-1
CAS:TGF-β1/Smad3-IN-1 is an orally administrable dual inhibitor of TGF-β1/Smad3 with anti-fibrotic activity, idiopathic pulmonary fibrosis (IPF).Formula:C30H34N4O6SPurity:99.83%Molecular weight:578.68Depiperazine-DM3189
CAS:Depiperazine-DM3189 inhibits the phosphorylation of SMAD 1/5/8 induced by bone morphogenetic protein 4 and can be used in biochemical experiments .Formula:C21H14N4Purity:99.69%Molecular weight:322.36ALK5-IN-83
ALK5-IN-83 (compound 13b) is an ALK5 inhibitor with an IC50 of 0.13 μM. It suppresses TGF-β1-induced Smad2 phosphorylation and cell motility in A549 cells.Formula:C20H23N7O2SColor and Shape:SolidMolecular weight:425.51YAP/TAZ inhibitor-4
YAP/TAZ Inhibitor-4 (Compound 45) acts as an inhibitor of YAP/TAZ, exhibiting inhibitory activity on TEAD transcriptional activation by preventing the interaction between YAP or TAZ and TEAD.Formula:C28H28F3N3O3Color and Shape:SolidMolecular weight:511.54Disitertide acetate
Disitertide acetate: a TGF-β1 and PI3K blocker, promotes apoptosis; inhibits receptor interaction.Formula:C70H113N17O24S2Purity:95.77%Color and Shape:White SolidMolecular weight:1640.88DC-TEADin02
CAS:DC-TEADin02 is an inhibitor of TEAD auto palmitoylation (IC50 = 197 nM). DC-TEADin02 can be in studies about development, regeneration, and tissue homeostasis.Formula:C19H17NO2SPurity:99.83%Color and Shape:SolidMolecular weight:323.41YAP-TEAD-IN-3
CAS:YAP-TEAD-IN-3 inhibitor YAP/TAZ-TEAD interactions Avi-human TEAD (4217-434) YAP-TEAD-IN-3 inhibits YAP reporter gene expression and NCI-H2052 cell proliferationFormula:C27H26ClF2N3O4Purity:97.55% - 98.71%Color and Shape:SolidMolecular weight:529.96SLLK, Control Peptide for TSP1 Inhibitor(TFA)
CAS:SLLK is a control peptide for LSKL.Formula:C21H41N5O6Purity:98%Color and Shape:SolidMolecular weight:459.58OPN-9652
CAS:OPN-9652 is a covalent TEAD inhibitor reversing drug resistance in BRAF-mutant tumors.Formula:C19H15F4NO2Purity:99.78%Color and Shape:White SolidMolecular weight:365.32Ref: TM-T212610
1mg49.00€5mg92.00€1mL*10mM (DMSO)104.00€10mg145.00€25mg255.00€50mg378.00€100mg573.00€TEAD-IN-16
TEAD-IN-16 (compound BC-011) is a potent inhibitor of TEAD, with an IC50 of 72.43 μM. This compound plays a significant role in cancer research.Formula:C16H14F3NO3Color and Shape:SolidMolecular weight:325.09258YAP/TEAD-IN-1
YAP/TEAD-IN-1 (compound 4) is a potent inhibitor of YAP and TEAD, exhibiting antioxidant properties. It demonstrates antiproliferative effects on tumor cells while showing minimal cytotoxic activity towards normal human cells.Formula:C32H30N8OColor and Shape:SolidMolecular weight:542.634YAP-TEAD-IN-1 acetate
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.Formula:C95H148ClN23O23S2Purity:98.11% - 99.98%Color and Shape:SoildMolecular weight:2079.92TGFβRI-IN-7
TGFβRI-IN-7 (compound 16W) is a potent inhibitor of TGFβRI. It effectively inhibits the phosphorylation of SMAD2/3 and reduces the viability of H22 cells, with IC50 values of 12 nM and 65 nM, respectively. In an H22 cell xenograft model, TGFβRI-IN-7 exhibits antitumor efficacy with a TGI of 79.6%.Formula:C27H32N6O2Color and Shape:SolidMolecular weight:472.582YAP-IN-1
YAP-IN-1 (Compound (+)-1) is an autophagy inhibitor specifically targeting YAP1. It binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 μM, promoting its degradation through the chaperone-mediated autophagy (CMA) pathway. This process inhibits the Rab7-mediated fusion of autophagosomes with lysosomes and decreases autophagy levels without affecting lysosomal function. YAP-IN-1 shows potential for cancer research, including in hepatocellular carcinoma and breast cancer.Color and Shape:Odour SolidWnt/Hedgehog/Notch Compound Library
A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
Color and Shape:Odour SolidTubastatin
CAS:Tubastatin inhibits TGF-β1-induced S6K phosphorylation, HIF-1α expression and VEG F expression.Formula:C21H22N2O2Purity:98.53%Color and Shape:SolidMolecular weight:334.41Super-TDU (1-31) (TFA)
Super-TDU (1-31) TFA, a peptide, inhibits YAP-TEAD; it has strong anti-tumor effects in gastric cancer models.Formula:C141H218N40O48·C2HF3O2Color and Shape:SolidMolecular weight:3355.5
