
Stem Cells
Stem cell inhibitors are compounds that specifically target stem cells and their signaling pathways, affecting their ability to self-renew and differentiate. These inhibitors are crucial in research focused on controlling stem cell behavior, understanding developmental processes, and developing therapies for diseases like cancer, where stem cells are thought to play a key role. At CymitQuimica, we offer a variety of stem cell inhibitors to support your research in regenerative medicine, developmental biology, and oncology.
Found 486 products of "Stem Cells"
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ROCK-IN-7
CAS:<p>ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].</p>Formula:C17H17N3O2SPurity:98%Color and Shape:SolidMolecular weight:327.4SWTX-143
CAS:<p>SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional</p>Formula:C19H18F3N3OPurity:98%Color and Shape:SolidMolecular weight:361.36GSK-3β inhibitor 8
CAS:<p>GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine</p>Formula:C20H20ClN5OSPurity:98.46%Color and Shape:SolidMolecular weight:413.92DT-6
CAS:<p>DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing</p>Formula:C89H130N20O29S2Purity:98%Color and Shape:SolidMolecular weight:2008.233,7-DMF
CAS:<p>3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation.</p>Formula:C17H14O4Purity:98%Color and Shape:SolidMolecular weight:282.29MRK-560
CAS:<p>MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.</p>Formula:C19H17ClF5NO4S2Purity:98.87%Color and Shape:SolidMolecular weight:517.92Chroman 1
CAS:<p>Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).</p>Formula:C24H28N4O4Purity:99.67% - 99.84%Color and Shape:SolidMolecular weight:436.5QL-1200186
CAS:<p>QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production following</p>Formula:C26H27N7O3Purity:98%Color and Shape:SolidMolecular weight:485.54JAK-IN-5
CAS:<p>JAK-IN-5 is a JAK inhibitor.</p>Formula:C27H31FN6OPurity:98.1% - 99.37%Color and Shape:SolidMolecular weight:474.57TP0427736
CAS:<p>TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x > ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.</p>Formula:C14H10N4S2Purity:97.26%Color and Shape:SolidMolecular weight:298.39JAK-IN-31
CAS:<p>JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 µM for JAK2, 0.01-0.1 µM for JAK3, and ≤0.01 µM for Tyk2,</p>Formula:C21H19N7O2S2Purity:98%Color and Shape:SolidMolecular weight:465.55STAT3-IN-B9
CAS:<p>STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.</p>Formula:C20H13NO5SPurity:98.19%Color and Shape:SolidMolecular weight:379.39ML115
CAS:<p>ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.</p>Formula:C15H15ClN2O4Purity:99.97%Color and Shape:SolidMolecular weight:322.74TGFβ-IN-5
CAS:<p>TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.</p>Formula:C20H16N4Purity:99.29% - 99.5%Color and Shape:SolidMolecular weight:312.37Casein kinase 1δ-IN-4
CAS:<p>"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."</p>Formula:C16H12N6SPurity:98%Color and Shape:SolidMolecular weight:320.37TCS 21311
CAS:<p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.</p>Formula:C27H25F3N4O4Purity:99.39% - ≥98%Color and Shape:SolidMolecular weight:526.51ABBV-712
CAS:<p>ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 μM, and is implicated in the regulation of autoimmune diseases</p>Formula:C24H28N4O5Purity:98%Color and Shape:SolidMolecular weight:452.5LX7101
CAS:<p>LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).</p>Formula:C23H29N7O3Purity:99.08%Color and Shape:SolidMolecular weight:451.52GNE-7883
CAS:<p>GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.</p>Formula:C28H29FN6O2Purity:97.61%Color and Shape:SolidMolecular weight:500.57STAT6-IN-2
CAS:<p>STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.</p>Formula:C28H31N5O2Purity:99.67%Color and Shape:SolidMolecular weight:469.58
