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Stem Cells

Stem Cells

Stem cell inhibitors are compounds that specifically target stem cells and their signaling pathways, affecting their ability to self-renew and differentiate. These inhibitors are crucial in research focused on controlling stem cell behavior, understanding developmental processes, and developing therapies for diseases like cancer, where stem cells are thought to play a key role. At CymitQuimica, we offer a variety of stem cell inhibitors to support your research in regenerative medicine, developmental biology, and oncology.

Found 486 products of "Stem Cells"

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  • ROCK-IN-7

    CAS:
    <p>ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].</p>
    Formula:C17H17N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:327.4
  • SWTX-143

    CAS:
    <p>SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional</p>
    Formula:C19H18F3N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:361.36
  • GSK-3β inhibitor 8

    CAS:
    <p>GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine</p>
    Formula:C20H20ClN5OS
    Purity:98.46%
    Color and Shape:Solid
    Molecular weight:413.92
  • DT-6

    CAS:
    <p>DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing</p>
    Formula:C89H130N20O29S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2008.23
  • 3,7-DMF

    CAS:
    <p>3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation.</p>
    Formula:C17H14O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:282.29
  • MRK-560

    CAS:
    <p>MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.</p>
    Formula:C19H17ClF5NO4S2
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:517.92
  • Chroman 1

    CAS:
    <p>Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).</p>
    Formula:C24H28N4O4
    Purity:99.67% - 99.84%
    Color and Shape:Solid
    Molecular weight:436.5
  • QL-1200186

    CAS:
    <p>QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production following</p>
    Formula:C26H27N7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:485.54
  • JAK-IN-5

    CAS:
    <p>JAK-IN-5 is a JAK inhibitor.</p>
    Formula:C27H31FN6O
    Purity:98.1% - 99.37%
    Color and Shape:Solid
    Molecular weight:474.57
  • TP0427736

    CAS:
    <p>TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x &gt; ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.</p>
    Formula:C14H10N4S2
    Purity:97.26%
    Color and Shape:Solid
    Molecular weight:298.39
  • JAK-IN-31

    CAS:
    <p>JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 µM for JAK2, 0.01-0.1 µM for JAK3, and ≤0.01 µM for Tyk2,</p>
    Formula:C21H19N7O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:465.55
  • STAT3-IN-B9

    CAS:
    <p>STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.</p>
    Formula:C20H13NO5S
    Purity:98.19%
    Color and Shape:Solid
    Molecular weight:379.39
  • ML115

    CAS:
    <p>ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.</p>
    Formula:C15H15ClN2O4
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:322.74
  • TGFβ-IN-5

    CAS:
    <p>TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.</p>
    Formula:C20H16N4
    Purity:99.29% - 99.5%
    Color and Shape:Solid
    Molecular weight:312.37
  • Casein kinase 1δ-IN-4

    CAS:
    <p>"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."</p>
    Formula:C16H12N6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:320.37
  • TCS 21311

    CAS:
    <p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ &amp; GSK3β; &gt;100x selective over JAK1, JAK2, TYK2.</p>
    Formula:C27H25F3N4O4
    Purity:99.39% - ≥98%
    Color and Shape:Solid
    Molecular weight:526.51
  • ABBV-712

    CAS:
    <p>ABBV-712 is a selective Tyrosine Kinase 2 (TYK2) inhibitor, demonstrating an IC50 value of 0.195 μM, and is implicated in the regulation of autoimmune diseases</p>
    Formula:C24H28N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:452.5
  • LX7101

    CAS:
    <p>LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 &lt;1 nM).</p>
    Formula:C23H29N7O3
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:451.52
  • GNE-7883

    CAS:
    <p>GNE-7883 is an inhibitor targeting TEAD transcription factor, inhibits cell proliferation and suppresses YAP/TAZ activation, and can be used to study YAP/TAZ-dependent tumors.</p>
    Formula:C28H29FN6O2
    Purity:97.61%
    Color and Shape:Solid
    Molecular weight:500.57
  • STAT6-IN-2

    CAS:
    <p>STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.</p>
    Formula:C28H31N5O2
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:469.58