Hippo pathway
Hippo pathway inhibitors are compounds that target and inhibit components of the Hippo signaling pathway, which plays a crucial role in regulating cell growth, proliferation, and apoptosis. Dysregulation of the Hippo pathway has been implicated in cancer development and stem cell function. Inhibitors of this pathway are valuable for studying the mechanisms of organ size control, tissue regeneration, and cancer progression. At CymitQuimica, we offer Hippo pathway inhibitors to support your research in cell signaling, oncology, and regenerative medicine.
Found 6 products of "Hippo pathway"
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MR24
<p>MR24 is a derivative of G-5555 and acts as an inhibitor of mammalian STE20-like (MST) kinases. It selectively targets MST3 and MST4, with EC50 values of 57 nM and 583 nM, respectively.</p>Formula:C26H29ClN6O3Molecular weight:508.19897I3MT-3
CAS:<p>I3MT-3 (HMPSNE) is a selective inhibitor of 3MST, targeting active site cysteine residues and permeating cell membranes.</p>Formula:C17H14N2O2SPurity:99.76%Color and Shape:SolidMolecular weight:310.37XMU-MP-1
CAS:<p>XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!</p>Formula:C17H16N6O3S2Purity:99.68% - 99.79%Color and Shape:SolidMolecular weight:416.48JA310
CAS:<p>JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].</p>Formula:C17H19N7OColor and Shape:SolidMolecular weight:337.38IHMT-MST1-58
CAS:<p>IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity.</p>Formula:C21H22N6O3SPurity:98.31% - 99.92%Color and Shape:SolidMolecular weight:438.5EMT inhibitor-1
CAS:<p>EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.</p>Formula:C12H12Cl2N2O2SPurity:99.53%Color and Shape:SolidMolecular weight:319.21
